hi sahs. I take Orlistat, have done since last July. It does work, but like anything, you have to put the effort in as well. It does cut out the fat, but i find so long as i stay within 15g fat per meal, there is no nasty side effects - everything remains normal IYSWIM
It is the threat of the side effects that worked for me as well, and i must admit to having a couple of incidents where i got too confident with what i could eat
Other than that, exercise is a biggie - i have to go for 4 weekly weigh ins, and the nurse knows straight away if i have been exercising or not, as there is quite a difference in the weight loss.
Good luck with it, and i must say, i have only heard of people being prescribed it who have at least 5 stone to lose. You must have a very supportive GP That's half the battle.
Good luck with it, and any questions, give me a shout