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Weight loss chat

A space to talk openly about weight loss journeys and challenges. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any diet.

Sertraline SSRI medication / weight gain..?

0 replies

melanie133 · 12/04/2026 10:43

I was on sertraline (lowest dose 50 MG) for almost 1 year-started May last year and came off about four weeks ago.

have always been between A UK size 6 and 8 and (luckily) never had to worry about my weight, even when I had my child the weight fell off naturally. I think I got a good metabolism from my dad who has always been very slim.

I don’t keep scales in the house and don’t weigh myself, so was absolutely shocked when I weighed myself at my parents house and realised I put on a stone in eight months!
cellulite has also appeared rapidly on the inside and back of my thighs when it has never been there before.
Has anyone else had this experience of sudden weight gain and cellulite on sertraline?
nothing else in my lifestyle has changed and I’m hoping now I’ve stopped the medication and with some exercise and diet changes the cellulite will go away before summer!
would love to hear any similar experience. it feels like sertraline completely wrecked my metabolism, and I’m hoping it will come back!

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