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Weight loss chat

A space to talk openly about weight loss journeys and challenges. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any diet.

Weight Loss Injection

5 replies

KellBell1987 · 29/01/2026 13:31

Hi all,

I have been using Mounjaro for the past six months. In the first three months, I did lose weight. I have been steadily increasing my dosage and am now on 10* *mg. The problem is that I am finding it less and less effective.
Should I simply keep increasing the strength?

Thanks, Kelly

OP posts:
ResusciAnnie · 29/01/2026 13:32

How much have you lost? Yes the idea is to keep increasing until you get results. Depends what you’re after though, I am sticking on 5mg for now but happy with 1lb a week loss. Some people would class that as ‘not losing’.

morningtrain · 29/01/2026 14:13

What do you mean by less & less effective?

SilenceInside · 29/01/2026 14:15

When you say "less and less effective" what do you mean? Is it that you are finding that you can eat more food than before and so can't stay in a calorie deficit? Or that your rate of weight loss has slowed down?

What is your daily diet like and what exercise do you do?

JadeOrca · 29/01/2026 19:38

I’ve been on MJ for over a year and got all the way up to 15mg. Found it lost its effect and gave myself a 8 week wash out period and started again on 2.5. It’s a slow burner but can feel it starting to do its thing again. Cannot recommend Lotus pharmacy enough for their support - they’ve been incredible.

maddiemookins16mum · 29/01/2026 20:06

I started back last May, I was 13 stone 12. Today I weigh 10 stone 6.
I did 2 x 2.5 pens
2 x 5 pens
1 x 7.5
1 x 10 pen
and I start my first 12.5 tomorrow.
Full disclosure….I lost the majority of my weight in the first 4 months (on the lowest dose pens) I’ve lost under a stone with the last two higher pens, I almost feel they aren’t working sometimes too. For example the 10mg pen I’ve lost 2.5lbs on in the last month! (That's an expensive 2.5 lbs!). I've hit plateau after plateau where nothing changes for weeks on end or I lose 2lbs and gain 1b.

I have gone low carb and very high protein. I’m 62 this year and now a very comfortable size 14 - in fact my size 14 jeans are now a bit too big. Previously I was an 18-20 (I’m 5ft 4). My goal weight is 10 stone which would give me a BMI of 23.5.

A friend of mine has suggested that my body may now just be at the right weight for me. I’m pretty good at calorie counting - aim for 1400 a day - sometimes I’m a little over and sometimes a little under. I have days when I’m hungrier than others
We have no snack food in the house - I simply don’t buy it. If I was hungry again tonight my choices would be an apple, a banana or at a push, a Baby bel cheese.
Today I’ve eaten 2 x Weetabix with semi skimmed milk and chopped banana, some homemade chicken, bacon and lentil soup, a small bowl of full fat proper Greek yoghurt and dinner was wholegrain rice with three different steamed veg and a grilled salmon fillet.
I’m not hungry tonight.

I joined a Gym in September and really enjoy it, the weight machines and especially the incline on the treadmill for 30 mins 3 x a week, plus Aqua Fit and swimming lengths.

After this 12.5 mg pen my ‘plan’ is to work back down the doses. It may be that when I get back to the 2.5mg again, I stay on that for a while to maintain.

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