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Weight loss chat

A space to talk openly about weight loss journeys and challenges. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any diet.

Why are you NOT on injections?

199 replies

Froum · 09/04/2025 17:39

Just curious why other people have chosen not to go down the glp 1 route.

For me I have just heard one too many horror stories. I am extremely grateful to be in a healthy (albeit overweight) body that I just can’t take the risk. I have a random phobia of vomit/nausea. Genuinely couldn’t think of much worse in terms of side effects.

Also, I have lost significant amounts of weight in the past. And once I get going I don’t find it too difficult. So I know I don’t really need the medication. I can keep it off too as long as I don’t use food as a crutch when going through a difficult time. The weight I’m losing right now al came on during my divorce process. I lived off lasagna and cheese boards. Just to cheer myself up. Luckily I am in a better place

And id rather have the money each month (thinking of treating myself to a cosmetic treatment and it’s more justifiable in my head if I think I’ve saved money from not spending it on wl jabs).

I really dont think poorly of people who choose medication. Just thought I should say that.

OP posts:
SilenceInside · 10/04/2025 18:33

They don’t “add nausea”. I have had a small amount of nausea on the initial starting dose for a few days, then none at all for about 8 months.

Nutmuncher · 10/04/2025 19:24

TalkToTheHand123 · 10/04/2025 17:35

Injecting feels like cheating. I feel if I ever succeed naturally, I will feel more pleased with myself.

It’s really not cheating just ask all those who’ve lost 2,3,4,5,6,7st on the WLI threads - it’s life changing and transformative. Why struggle unnecessarily?

QueefQueen80s · 10/04/2025 20:13

SilenceInside · 10/04/2025 18:33

They don’t “add nausea”. I have had a small amount of nausea on the initial starting dose for a few days, then none at all for about 8 months.

Everyone is different, I have friends who have constant nausea and stomach discomfort which itself puts them off eating for all reasons.

WearyAuldWumman · 10/04/2025 20:15

I'd love to try the injections, but - TMI - I have IBS, so I'm worried about the side effects.

SilenceInside · 10/04/2025 20:18

@QueefQueen80sthey don’t add nausea. Some people might be nauseous, but it isn’t universal by a very long way and it isn’t an intended effect. If your friends all have constant nausea and stomach issues then they should speak to their pharmacy about what to do about that, and perhaps going down a dose might help. Or diet changes, or other measures. You could let them know that it isn’t something to expect or that they need to put up with.

QueefQueen80s · 10/04/2025 20:20

SilenceInside · 10/04/2025 20:18

@QueefQueen80sthey don’t add nausea. Some people might be nauseous, but it isn’t universal by a very long way and it isn’t an intended effect. If your friends all have constant nausea and stomach issues then they should speak to their pharmacy about what to do about that, and perhaps going down a dose might help. Or diet changes, or other measures. You could let them know that it isn’t something to expect or that they need to put up with.

They might just be more sensitive to it, that’s good that it isn’t like that for everyone as it sounds awful.

Britneyfan · 10/04/2025 20:25

For me it’s partly cost (could definitely think of other things to do with the money though I am also prepared to pay that amount to be slim and consider it good value!) and partly fear about side-effects, I’ve had a miserable 18 months or so with gallstone related issues causing severe nausea and lack of appetite, had gallbladder surgery a few months ago and am just starting to feel human again and feel I just can’t make myself feel awful all over again. I know nausea is not guaranteed but it seems fairly common to me from talking to others. And lack of appetite is part of the point of it right? But I actually don’t like not having an appetite, when I’ve had that through gallstone problems or through depression I actually end up eating more and gaining weight because I can’t be bothered to eat until I’m suddenly ravenous and craving junk food. I also do worry a little about pancreatitis, I know it’s rare but it does happen. I’ve also lost quite a bit of weight through the gallstone issues anyway, so have decided to keep going with weight loss without it while that is working and save the money and side effects risks. I am plateauing though. I’m going by to re-evaluate in 3-6 months.

Nutmuncher · 10/04/2025 21:37

WearyAuldWumman · 10/04/2025 20:15

I'd love to try the injections, but - TMI - I have IBS, so I'm worried about the side effects.

Anecdotal but a colleague/ friend has been on MJ around 2 months now and it has dramatically improved her IBS- to the point where she is thinking she may need to stay on 2.5mg for the foreseeable future because the difference has been life changing.

garlicbreadsticks · 10/04/2025 22:34

Long term side effects here. I could manage gastrointestinal side effects but not knowing what might be in front of me in future. I have been wondering glad bladder and pancreas side effects. I think I wait some years to see if there is any serious long term effects like cancer.

WearyAuldWumman · 10/04/2025 22:40

Nutmuncher · 10/04/2025 21:37

Anecdotal but a colleague/ friend has been on MJ around 2 months now and it has dramatically improved her IBS- to the point where she is thinking she may need to stay on 2.5mg for the foreseeable future because the difference has been life changing.

Oh, that's interesting!

StarDolphins · 10/04/2025 22:41

Hair, my friend is a hairdresser and can tell the ones on it by their thinning hair. Also, what the plan would be when at goal weight?! It just looks like a recipe for a cycle of weight on/weight off to me.

ItsAWonderfulDayForPie · 10/04/2025 22:44

Intermittent fasting works for me and means I’m spending less on food. The idea of paying a lot to lose weight, only to gain it back when the injections stop seems bittersweet.

TalkToTheHand123 · 10/04/2025 22:49

Nutmuncher · 10/04/2025 19:24

It’s really not cheating just ask all those who’ve lost 2,3,4,5,6,7st on the WLI threads - it’s life changing and transformative. Why struggle unnecessarily?

I don't understand why I would need to and how their view means their view is more valid than mine.

I'm not saying don't inject, just giving my view and reason why I won't be injecting.

SilenceInside · 10/04/2025 22:49

StarDolphins · 10/04/2025 22:41

Hair, my friend is a hairdresser and can tell the ones on it by their thinning hair. Also, what the plan would be when at goal weight?! It just looks like a recipe for a cycle of weight on/weight off to me.

Hair loss, telogen effluvium, is a risk for any weight loss programme - it isn't specific to weight loss injections. It is temporary and self correcting within about 3 to 6 months. Temporary hair shedding is not a side effect that would interfere with my very necessary weight loss.

What is the plan when people on SW, WW, IF, Fast 800 etc etc reach their goal weight? The risk of weight regain is no better on any of those, we know this, as people are repeat customers and we have a long term obesity problem that isn't resolving despite the proliferation of these weight loss plans. I have been in a cycle of weight on/weight off since childhood. This is the longest period of weight loss, on Mounjaro, that I have ever managed before. I will continue to take it, if I cannot maintain the weight loss on my own, after a year or more of losing weight.

lavenderdinosaur · 10/04/2025 22:53

Because it’s a substance that you inject into yourself that makes you sick and probably many other side effects… people on here hate drinking and vaping but see no issue with this!!

StarDolphins · 10/04/2025 23:00

SilenceInside · 10/04/2025 22:49

Hair loss, telogen effluvium, is a risk for any weight loss programme - it isn't specific to weight loss injections. It is temporary and self correcting within about 3 to 6 months. Temporary hair shedding is not a side effect that would interfere with my very necessary weight loss.

What is the plan when people on SW, WW, IF, Fast 800 etc etc reach their goal weight? The risk of weight regain is no better on any of those, we know this, as people are repeat customers and we have a long term obesity problem that isn't resolving despite the proliferation of these weight loss plans. I have been in a cycle of weight on/weight off since childhood. This is the longest period of weight loss, on Mounjaro, that I have ever managed before. I will continue to take it, if I cannot maintain the weight loss on my own, after a year or more of losing weight.

The plan for maintaining on SW/WW is to maintain by eating more/less. No harm done.

Thats a whole different thing to injecting an appetite suppressant (with no long-term data) then getting to your goal weight and either being underweight or overweight all controlled with a jab.

SilenceInside · 10/04/2025 23:05

Why would it not be possible to continue to eat more/less after reaching my final goal and stopping the injections? Having been used to eating less for a year or more in my case, and eating in a completely different way to what made me obese? And being able to be significantly more active due to being a healthy weight.

SilenceInside · 10/04/2025 23:06

@lavenderdinosauralcohol and vapes are not medication, so they’re an odd comparison to make. The benefits of this medication for obese people outweighs the possible risks of taking it, by a long way. Hence it being approved by the MHRA for weight loss. Hence people being supportive of it on here.

TheChosenTwo · 10/04/2025 23:20

WearyAuldWumman · 10/04/2025 20:15

I'd love to try the injections, but - TMI - I have IBS, so I'm worried about the side effects.

I’ve been reading out of curiousity, I’m taking MJ so didn’t really want to start chiming in.
But I would like to reply to your comment because I also had very varying bowel movements ranging from, well okay I won’t go into much detail here, I’m sure you can well imagine. Anyway, since starting MJ I’ve never had better gut health - I’m eating so much better than I ever have done. Virtually nothing UPF at all, loads of raw foods (salads) and seeds and nuts and meat and my dodgy and unpredictable bowels have been pretty much transformed. Have had a couple of moments but in 6 months barely anything of note.
Anyway, not here to try and persuade you or anyone else, but just wanted to let you know my experience because it has been a really positive side effect that I hadn’t anticipated.

Crikeyalmighty · 10/04/2025 23:25

I’m actually on week 2 of mounjaro but am not taking anymore after the first month - main reason being that on reflection the main reason others seem to feel the need doesn’t really apply to me- I’ve never been a grazer or a food noise person - I just like decent ( too big) portions of good quality food- I like cooking and I like wine - 1/2 a bottle 2 and sometimes 3 times a week . I did manage to lose 2stone 5 18 months ago in 9 months and then somehow lost the will. And need to losesnother3 stone. I think I thought it would be a good kickstart but both jabs so far have made me feel lousy for 3 days- like a giant hangover combined with a morning sickness type feel and low grade tummy ache- I believe it does lessen but on reflection I think I can do it in a healthier way albeit slower - I used appetite suppressants intermittently last time with Berberin and got good results without the feeling dreadful so may do that again - I appreciate it really works for some and certainly I felt too ‘off’ to eat properly- on the bonus side I have lost 4lbs.

WearyAuldWumman · 10/04/2025 23:26

TheChosenTwo · 10/04/2025 23:20

I’ve been reading out of curiousity, I’m taking MJ so didn’t really want to start chiming in.
But I would like to reply to your comment because I also had very varying bowel movements ranging from, well okay I won’t go into much detail here, I’m sure you can well imagine. Anyway, since starting MJ I’ve never had better gut health - I’m eating so much better than I ever have done. Virtually nothing UPF at all, loads of raw foods (salads) and seeds and nuts and meat and my dodgy and unpredictable bowels have been pretty much transformed. Have had a couple of moments but in 6 months barely anything of note.
Anyway, not here to try and persuade you or anyone else, but just wanted to let you know my experience because it has been a really positive side effect that I hadn’t anticipated.

Thank you - that's appreciated.

I'm definitely not coeliac, but I do have a gluten intolerance and have to avoid dairy. I've been trying the FODMAP diet, an attempt to figure out which foods trigger me.

I've already cut out greasy foods, etc and I'm avoiding processed food.

Nutmuncher · 10/04/2025 23:32

Crikeyalmighty · 10/04/2025 23:25

I’m actually on week 2 of mounjaro but am not taking anymore after the first month - main reason being that on reflection the main reason others seem to feel the need doesn’t really apply to me- I’ve never been a grazer or a food noise person - I just like decent ( too big) portions of good quality food- I like cooking and I like wine - 1/2 a bottle 2 and sometimes 3 times a week . I did manage to lose 2stone 5 18 months ago in 9 months and then somehow lost the will. And need to losesnother3 stone. I think I thought it would be a good kickstart but both jabs so far have made me feel lousy for 3 days- like a giant hangover combined with a morning sickness type feel and low grade tummy ache- I believe it does lessen but on reflection I think I can do it in a healthier way albeit slower - I used appetite suppressants intermittently last time with Berberin and got good results without the feeling dreadful so may do that again - I appreciate it really works for some and certainly I felt too ‘off’ to eat properly- on the bonus side I have lost 4lbs.

I would try to persevere with the MJ, aside from the weight loss it will help you with your alcohol consumption which is no doubt going to be a factor in being overweight plus feeling lousy whilst using the medication. 1 and a half bottles each week is at the high end of the recommended units for women.

Mounjaro can really help when it comes to booze.

Crikeyalmighty · 10/04/2025 23:46

@Nutmuncher I’m not drinking at all whilst on it

PrioritisePleasure24 · 11/04/2025 07:17

My dad was on it for type 2 diabetes but is heavy. After a couple of months he just stopped eating. Barely eating anything and at 70+ plus and a insulin dependent diabetic this was really not good.

I think they are great for people that are very overweight/obese and that have lots of health problems/risks because of this. What i can’t understand is people lying and sending fake photos to lose essentially a few pounds or aren’t actually even overweight. I think it’s not worth the side effects and it’s playing dangerous games with their bodies and mental health. I do agree with the pp who said they think they could increase ED. Also needs better regulation.

SuperTrooper14 · 11/04/2025 07:41

ScratchyMcScratchface · 10/04/2025 11:00

I do think it will lead to a massive problem with eating disorders in the longer term.

This is what my GP thinks will be the long-term impact of these drugs (aside from the general concerns about side effects). There is widespread anecdotal evidence that the food noise not only comes back with a vengeance when you stop, but that it's even louder than previously. It's easy to see how someone could spiral into binge eating in a way they didn't suffer before starting the injections.