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Weight loss chat

A space to talk openly about weight loss journeys and challenges. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any diet.

Why are you NOT on injections?

199 replies

Froum · 09/04/2025 17:39

Just curious why other people have chosen not to go down the glp 1 route.

For me I have just heard one too many horror stories. I am extremely grateful to be in a healthy (albeit overweight) body that I just can’t take the risk. I have a random phobia of vomit/nausea. Genuinely couldn’t think of much worse in terms of side effects.

Also, I have lost significant amounts of weight in the past. And once I get going I don’t find it too difficult. So I know I don’t really need the medication. I can keep it off too as long as I don’t use food as a crutch when going through a difficult time. The weight I’m losing right now al came on during my divorce process. I lived off lasagna and cheese boards. Just to cheer myself up. Luckily I am in a better place

And id rather have the money each month (thinking of treating myself to a cosmetic treatment and it’s more justifiable in my head if I think I’ve saved money from not spending it on wl jabs).

I really dont think poorly of people who choose medication. Just thought I should say that.

OP posts:
SuperTrooper14 · 11/04/2025 07:45

SilenceInside · 10/04/2025 23:05

Why would it not be possible to continue to eat more/less after reaching my final goal and stopping the injections? Having been used to eating less for a year or more in my case, and eating in a completely different way to what made me obese? And being able to be significantly more active due to being a healthy weight.

It's the food noise that's the issue. Yes you have clearly developed a really healthy way of eating and are exercising more, but what happens when the drug stops suppressing your urge to eat?

QueefQueen80s · 11/04/2025 07:48

SuperTrooper14 · 11/04/2025 07:45

It's the food noise that's the issue. Yes you have clearly developed a really healthy way of eating and are exercising more, but what happens when the drug stops suppressing your urge to eat?

Yes it’s easier to have good habits when you don’t want to eat crap..

SuperTrooper14 · 11/04/2025 07:50

Having now just caught up with the entire thread, I have to say, the defensiveness of injectable users is really something else! We get it, you think WLI are great, but it's okay for others to not want to try them and for them to share their valid reasons for not wanting to. If you want to espouse what you consider to be injectables' virtues in your eyes then there are plenty of other threads you can comment on rather than hijacking this one!

QueefQueen80s · 11/04/2025 07:52

Nutmuncher · 10/04/2025 21:37

Anecdotal but a colleague/ friend has been on MJ around 2 months now and it has dramatically improved her IBS- to the point where she is thinking she may need to stay on 2.5mg for the foreseeable future because the difference has been life changing.

That’s one of the few positives I’ve heard, the slowing down of digestion helping people with ibs, chrohns, anything where the gut is sensitive and over stimulated

DinoLil · 11/04/2025 07:54

I can't afford it. I would qualify on the NHS but my GP won't prescribe because I'm not pre-diabetic.

I have lost 2st since rehoming a dog in September though!

Phunkychicken · 11/04/2025 08:01

I have been declined due to my health. Was quite relieved. Have gut dysmotility, thyroid nodules, have had 3 suspected womb cancer scares and 2 actual skin cancers (melanoma and bcc). Every few months have a gastro attack of 20+ goes of diarrhoea a day plus feeling awful. Too risky.

Am obese with high cholesterol and will be 50 later this month, so guess, as ever it’s down to me and me only to sort myself out

Nottodaty · 11/04/2025 09:22

For me it’s my relationship with food that would need to change. I comfort eat and hold weight a lot different now I’m closer to 50.

I think it’s a wonderful tool but for me I worry when you come off it. So slowly trying the old school way and it’s working but I still occasionally binge when having a hormonal day!

I’ve known two people who have had their stomach reduced operation and both have now put the weight back on over time. One has considered injections but wants to deal with her food issue first otherwise she worried she will just get in a bad cycle again.

I would never judge anyone. It’s frustrating for me dieting and exercising and not seeing the scales move fast but slowly overtime. Being overweight is so tough.

TheRoundTable1983 · 11/04/2025 09:45

SilenceInside · 10/04/2025 23:05

Why would it not be possible to continue to eat more/less after reaching my final goal and stopping the injections? Having been used to eating less for a year or more in my case, and eating in a completely different way to what made me obese? And being able to be significantly more active due to being a healthy weight.

I think logically you are right. You should be able to, but add hunger back in to the equation and it then willpower has to be thrown back into the mix too. The feeling of little to no hunger and no food noise was the most incredible feeling, but it's an artificial feeling. Take the meds away and you are reliant on discipline, diligence and total self awareness to keep the weight off using only the good habits built whilst using MJ. In theory, it's totally doable. In reality, it won't be for a lot of people.

Grumpyoldpersonwithcats · 11/04/2025 10:00

To be fair - most weight loss efforts ultimately fail because when whatever 'crutch' is removed, (be it injections, the support of a programme like WW, getting to a target weight and then relaxing, or even just getting bored of the diet), then it's likely that the weight loss will be reversed.
Interestingly I don't know anyone in RL using injections for weight loss (or at least don't know anyone who has told me!) which was why I didn't even consider it. I don't judge anyone who does - seems a great way to lose a lot of weight quickly - my only concern would be the impact of coming off the drugs.
My weight loss effort (purely dietary) has now stabilised but I'm keeping myself honest and avoiding putting any back on by recording a daily weigh in. I've made the weigh-in my 'crutch'.

Guistarry · 11/04/2025 10:06

TheChosenTwo · 10/04/2025 23:20

I’ve been reading out of curiousity, I’m taking MJ so didn’t really want to start chiming in.
But I would like to reply to your comment because I also had very varying bowel movements ranging from, well okay I won’t go into much detail here, I’m sure you can well imagine. Anyway, since starting MJ I’ve never had better gut health - I’m eating so much better than I ever have done. Virtually nothing UPF at all, loads of raw foods (salads) and seeds and nuts and meat and my dodgy and unpredictable bowels have been pretty much transformed. Have had a couple of moments but in 6 months barely anything of note.
Anyway, not here to try and persuade you or anyone else, but just wanted to let you know my experience because it has been a really positive side effect that I hadn’t anticipated.

You're really genuinely surprised that not eating crap helped with your IBS?

PrettyMessy · 11/04/2025 10:08

The benefits of WLI like Mounjaro, extend far beyond weight loss. I can’t really understand anyone that’s overweight, qualifies and can afford it not at least trying it.

My BMI when I started was 28.6 and it’s now 21.3. It’s been the easiest thing in the world to me, with no side effects whatsoever.

Outofthepan · 11/04/2025 10:11

Guistarry · 11/04/2025 10:06

You're really genuinely surprised that not eating crap helped with your IBS?

But I assume that the poster had been able to change their diet because of mounjaro.

It’s easy to talk about discipline/willpower etc if you don’t understand how people struggle with their relationship with food.

Froum · 11/04/2025 10:16

Is there data to back up that most people regain the weight when coming off wl jabs?

edit:

chat got said the following:

the data consistently show that most people regain a significant portion of the weight after discontinuing GLP-1 drugs (like semaglutide—Ozempic, Wegovy—or tirzepatide—Mounjaro, Zepbound).

tbh anecdotally my observations don’t support that. I know two ropes have taken MJ and come off it. They gained a bit of weight when stopping but have gained nowhere near 2/3 of their previous weight loss

OP posts:
LindorDoubleChoc · 11/04/2025 10:17

SuperTrooper14 · 11/04/2025 07:50

Having now just caught up with the entire thread, I have to say, the defensiveness of injectable users is really something else! We get it, you think WLI are great, but it's okay for others to not want to try them and for them to share their valid reasons for not wanting to. If you want to espouse what you consider to be injectables' virtues in your eyes then there are plenty of other threads you can comment on rather than hijacking this one!

Edited

I'm quoting your post because I think it needs saying again! Absolutely incredible, almost unbelievable, that so many posters using WLI are posting on a thread titled WHY ARE YOU NOT ON INJECTIONS?

Lord above.

SuperTrooper14 · 11/04/2025 10:18

PrettyMessy · 11/04/2025 10:08

The benefits of WLI like Mounjaro, extend far beyond weight loss. I can’t really understand anyone that’s overweight, qualifies and can afford it not at least trying it.

My BMI when I started was 28.6 and it’s now 21.3. It’s been the easiest thing in the world to me, with no side effects whatsoever.

So you have decided to post that on a thread where the majority don’t qualify or cannot afford it. Lovely.

Crikeyalmighty · 11/04/2025 10:46

@LindorDoubleChoc I posted because although I ‘am ‘ on them (but only two weeks) I won’t be persisting and gave my reasons why . I do think it’s a bad thing to post as if it’s a total miracle worker - that way it feels a bit like a cult. It doesn’t just ‘melt’ fat away without effort. you still have to be on a strict calorie control diet with little fat and little if anything involving spice and minimal if any alcohol - mainly I can’t hack feeling dreadful 3 days out of 7 - and that the food noise aspect for me isn’t relevant- I do know side effects are a personal thing but for me they outweigh the benefits and I can lose weight without if I put my mind to it as have done so before- i just lost the will after 8 months and stopped weighing myself too which was a big mistake. I can see for anyone who has no will power at all and needs to feel full as much as possible then they might be useful - and they are certainly useful for diabetics from the blood sugar aspect - as you say though it’s not a cheap option at all and you do have to accept that there ‘may’ be some side effects that aren’t pleasant - for anyone who can’t take them due to cost or immune conditions but feels the ‘feeling full’ would help - it might be worth trying the herbal appetite suppressants for a while- I’m going back to that myself as can use intermittently and will do so on holidays or business when it can be harder to be quite so careful and that’s how I got weight off last time- I only put it back ( and only a third of it) because I totally abandoned portion control , calorie counting and stopped weighing

ehb102 · 11/04/2025 10:55

I don't have food noise. When my underactive thyroid is medicated correctly I lose weight easily as I have good habits and lots of nutritional knowledge.

MissMarplesNiece · 11/04/2025 11:33

I've only known one person in real life who tried a WLI, I can't remember which one it was. She had awful side effects and had to stop using it.

I think they've been seized upon as a miracle without considered thought about long term consequences. I wonder if the people now in their 30s who are using them are anticipating using "maintenance doses" for the rest of their lives - for the next 30 or 40 years. Most medication that we end up taking long term - statins for example - can have long term effects on our bodies, and people generally start taking those later in life so for not as long.

@Froum The people you know who have come off WLIs and have gained only a little bit of weight back - surely most weight gain is slow and after 5 years they will have regained a lot more.

Gall10 · 11/04/2025 11:36

ForLovingAquaSheep · 09/04/2025 17:42

You can't be putting a foreign substance in your body without a long-term side effect.

Appreciate for some the trade off is their immediate health but I'm lucky in that if I stick to a meal plan etc then the weight comes and stays off. I know I can be a right greedy get and will suffer for it, but that's on me and I have to eat like a saint the other side of it.

I could have written this! The only weight loss that works long term is eat less and do more…it’s a physiological fact!

Outofthepan · 11/04/2025 12:36

This is a really great explanation of “good noise” by Sohee Fit, who’s a reputable fitness adviser, sensible, no fads,

https://www.instagram.com/reel/DHJr6T6SZYs/?igsh=MXZsd29kNnF5ZGFicw==

Instagram

https://www.instagram.com/reel/DHJr6T6SZYs/?igsh=MXZsd29kNnF5ZGFicw%3D%3D

Outofthepan · 11/04/2025 12:43

*food noise, definitely not good noise

PenneyFouryourthoughts · 11/04/2025 12:55

Cost. Also, injections give me the ick. I’d rather try more old fashioned methods.

Goody2ShoesAndTheFilthyBeast · 11/04/2025 12:56

Can't afford them.

WateryBottle · 11/04/2025 12:59

Gall10 · 11/04/2025 11:36

I could have written this! The only weight loss that works long term is eat less and do more…it’s a physiological fact!

Ok but that doesn’t work for people with oppressive food noise, that’s the point.

I’m not on them because BMI too low, but the reason I haven’t got an online prescription is I’m worried about how I’ll feel coming off them as I don’t think I’d maintain the weight loss without the urge to eat being suppressed.

Inmydreams88 · 11/04/2025 15:37

I lost 7 stone naturally and maintained it for nearly 10 years, now I have 2 stone of baby weight to loose but I personally wouldn’t even think about taking it because I’m a hypochondriac and I would worry about the potential long term risks, and even if there wasn’t any a lot of people say they feel sick and after my pregnancy sickness I would never intentionally make myself feel that way. My BMI isn’t high enough for it anyway, but maybe I would feel differently if had a-lot
more weight to loose. I can definitely understand why people want to do it.

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