Anyone gone cold turkey and happy to share what happened

[Wendyworm]

Anyone gone cold turkey after significant loss and significant time on them.
Just wondering what side effects to expect

I have been taking mj for 18 months. Been on 15mg for a good while now.

I have lost 117lb so far .

I have roughly between 20-40lb to go (I’m going to see how I feel at each stage- another 10lb would get me to an overweight bmi so that’s first step)

I have made my peace with being on 15mg untill Christmas and then reassessing.

the only barrier for me is the cost . We don’t have a large income and I know that there would be so much we could do with that extra £300 that would benefit the whole family. I have picked up an extra day at work a week just to cover it 🤬

ideally I would be able to tirate down to say 10mg over the course of the next year.

im hoping the new tablets make things cheaper (they seem more spendy atm)

I also know I need to improve my exercise but it seems a large hurdle atm. (Picking up an extra days work isn’t helping with tiredness 😩)

it’s a one month at a time waiting game. But I can’t believe how much I have lost. I have struggled with weight and stupid diets since aged 9 this feels like a magical medicine really (if I was Rich 🤭)

The 15mg stopped working for me eventually which is the only reason I quit. No sense paying all that money for no results. Luckily I’ve been able to maintain after a slight gain when I first stopped.

I hope you reach your target soon. It’s such game changers, isn’t it?

Had it removed 30 years ago ..
But I think there can still be issues later with stones and sludge

I can't really afford to ,I'm paying £300 a month as it is and I can't work out if I'm getting pain in the gallbladder area ..which is making me panicky as it was the worst pain in my life when I had attacks before I had it out

I’ve had weight loss surgery and now on Mounjaro… with both it doesn’t give you a personality change so unless you change your relationship with food the weight with surgery and WLI will come back on.

In my 40s now and I know this old gal won’t suddenly develop a love for salads when there is a carb in front of her so I’m on it for life I think.

Yes of course I understand that they are very expensive, but the principal remains the same people like me need this medication and I will need it for life perhaps at a lower dose but I know I can’t come off it

I lost 9 stone on mj and tapered down before stopping a year ago, I’ve put on half a stone since I stopped but I’ve put on quite a lot of muscle. It’s hard to keep it off though and I’ve had to change my whole lifestyle, I run twice a week, strength train five times a week, 15,000 steps a day and I still track my calories at my maintenance. I like to volume eat, so lower calorie foods but a lot of them and a lot of protein to keep me full

I. Supposed to take my next jab tomorrow
I can't decide what to do
And next
week I need to re order another 12 mg if I'm staying on it

Warning a long post

@Wendyworm, a few questions.
Are you speaking to your provider about your issues/concerns?
Are you seeing your gp re the pain you are feeling?
Where are you on your weightloss journey? Have you been overweight all your life, or was it post life events? Are we talking 3/4 stone or less OR 5 stone plus?

I heard a really interesting podcast by M Robbins with an American doctor, expert in obesity medicine, endocrinology and metabolic disorders. Highly recommended, also the recent Zoe podcast, both free to view/hear/read.

Obesity is a disease, for some lifelong, caused by a combination of 4 factors:
Lifestyle -diet, sedentaryism, exercise, stress, sleep etc
Hormones- PCOS, perimenopause, menopause..and many others
Ageing- muscle loss, reduced bmr/tdee but if no change in intake, weightgain
Obesogenic environment -industrialisation of food manufacture, processed foods, advertising, reduction in walking cycling activities of daily living

Addressing food intake alone doesnt even cover lifestyle. WLIs operate in a range of ways, some currently understood..others the scientists are only beginning to understand as this vast natural experiment occurs. So far most research has been related to diabetics and more recently the obese. But we dont have quality research on behaviour pist weight loss and maintenance..mainly because this is all so new (relatively speaking).

So what's the answer for you? I dont know but in the same way as the causes of obesity are multiple factors, successful maintenance will have multiple aspects and be individual to each of us. Undoubtedly watching intake, keeping up fibre and protein, and hydration, maintaining muscle mass, exercising and maximising tdee And for some keeping on a dose of wlis..but possibly titrated right down.

Meantime new wli products will continue to appear, prices will fall (bit it may take some time)
So it's a long game..watch this space..and if you havent speak with your gp/provider. Best of luck

I had an awful time as well after just 3 doses of mounjaro

I think you need to really read up on how this medication works.

you can’t take people’s personal anecdotes as gospel and a blueprint for how it will work for you.

the medication works on a physiological level. In obese people, it works to reduce inflammation, reduce appetite, insulin levels - all sorts.

nobody can give you a success story yet either. Far too soon.

but from what I read and see, it’s becoming increasingly likely that most people will regain if they stop taking the medication - it isn’t about what you’ve learned about nutrition, it’s everything to do with the drugs effect on your body

you need to properly research and gain an understanding of what you’re taking and why and what maintenance might look like for you

@Wendyworm if you're getting 12.5mg at the moment, you don't need to pay £300, there are pharmacies who do it for about £50 less eg Medicine Market Place at £246.

If you've got a pen on the go at the moment, I would consider just continuing for the moment whilst you work out a forward plan. If you have constant pain, then you should see your GP and you could also contact your current prescriber for advice to check you are ok to continue.

If the pain isn't Mounjaro related and you are ok to continue, then you could plan to taper down the doses whilst working on maintaining your current weight. You can reduce costs by continuing to get a 12.5mg pen but doing smaller doses from it and using the leftover medication in each pen after the equivalent of 4 normal doses have been delivered. Then you would only need to order a pen every 7 to 8 weeks. You may find that you can maintain your weight on a lower, and therefore cheaper, dose.

Great advice @SilenceInside , across a range of the WLI threads on mumsnet, there's excellent experience and knowledge to be found about all aspects of the journey

I havent put the weight back on. I titrated down slowly and still count calories. I weigh myself every single morning and if Ive put on a couple of pounds I lose it straight away and dont wait until its half a stone.
I also got rid of all my clothes that arent my current size 10 so if I gain weight Id have to go out in PJs as there isnt anything else.
If the hunger overwhelms me I drink a pint of water straight down and if its still there I drink another one. That gets rid of the hunger pangs alright.
I cant afford to put the weight back on. Ive spent hundreds of pounds on GLP1s.

Its so sad. I walk past a bench in our local park to someone who lost her life to obesity after weight loss surgery. More than 10 stone off before she started to regain. For some its a life long battle.

I came off cold turkey 6 weeks ago. I have put 7lb straight back on, that’s 1lb a week.

i already eat healthy food, walk every day, weight train, but I’m also perimenopausal and have Hashimotos thyroid disease.

I am restarting today and plan to go up to higher doses to lose weight back to healthy BMI, but after then I will expect to use it for life just in order to maintain, in one form or another - the new pills look to be cheaper.

I have lost just under 9 stone on WLI. My GP told me to expect to be on WLI for the rest of my life. I still have some weight to lose. I am going to try titrating down at some point. I have to view the money I am spending as being essential to support me to live a healthier life.

But have to say Op that you seem very ignorant of the way that the drug that you are taking actually works.

I titrated down after 5+stone loss. 3months with nothing and I’m maintaining. I’ve now maintained this weight for about 8months but my body composition continues to change. My entire life is different now - I’m an exercise fiend, I’m careful with what I eat and I know the calories in things. I’ve spent so much time
and effort to reach this point I couldn’t cope with regaining it all. So it’s continued effort, just in a different way. But life now is too good for me to want to go back to how I used to be. So it’s possible OP. one day at a time, I think.

I've got autism and ADHD and I can't retain information well .so I did research lots before I went on it ..but seem to of forgotten it now ..seem to have some health anxiety popping up as well ..

No ,no ,18 months ,yes ,2 stone to go
Thanks for long message
Have half pen left , haven't decided what to do yet

Op 60 percent of people regain the weight from surgery, simply as the stomach stretches and they go back to square one.

comong off the jabs doesn’t mean the weight magically appears back. You regain weight like you do normally. If you eat more than you burn off then you gain weight. Which is whay people are doing.

hunger isn’t different to before, just you forget what it feels like, as the meds no longer control blood sugar and insulin the cravings come back. Your body reverts to exactly as it was before you took the meds.

I've decided to come of slowly,I've re ordered the next pen down .
Will take things steady and slow
Thanks for the advice guys x