Dose question Mounjaro

[Rosey099]

Hi

I have been on MJ almost a month now, I took my 4th jab of my 2.5 pen yesterday

I have had minimal side affects apart from muscle aches for one day after first jab, tiredness and was sick once in my second week as think I ate something that didn't agree with me

I jab on a Monday as I wanted to be able to enjoy my weekends still as I socialise alot on weekends which usually involves food

i lost 5lbs my first week, second week I gained 1lb and since then I've been losing and gaining the same 2lbs so I've probably lost in total around 6lbs with the majority of that being the first week which tbh I am quite disappointed in , i have still been in a calorie deficit i use nutracheck and have done for years and I drink 2 litres min water a day

I feel fuller quicker and have totally gone off some things I used to love like wine and Coke Zero and even tea I have not had any of that for almost a month , i have still drank alcohol at the weekends when out with friends and eaten out but nowhere near as much food and drink as I would have before the jab

the week I was sick I didn't eat much at all and that was the week I gained the 1lb!!

also the problem is I jab and weigh ona. Monday and as I'm eating the most at weekends when I weigh on the Monday the scales are showing a gain which is very demotivating

I know some people say 2.5 doesn't do much but I know people who stayed at that dose and lost over two stone and I wanted to stay as low as possible

I only have two stone to lose, I did calorie counting before this and lost 3 stone but put a stone back on.

I need to order my next pen and my question now is do I go up to 5mg which i didn't really want to do yet or do I jab later in the week to have more suppression on weekends ?

It sounds like going up to 5mg and/or injecting before the weekend would be helpful for you.

You could jab a day earlier for a couple of weeks to pull your day back gradually to Thursday/Friday. Or a day later to push it further ahead.

If staying at 2.5mg, I would inject at 6/5 days interval to pull the injection day back. This would also mean you had a higher dose in your body.

If going up to 5mg, I would change my injection day by pushing it forward and injecting on day 8 for a while, because going up a dose AND injecting at 6 days would be a very big increase all in one go.

Hope I’ve explained all that clearly!

Thanks @ShrankLastWinter for some reason I have put on 3lbs since Saturday .. it seems to work during the week then I'm undoing everything at the weekend. I had my consultation this morning and she's said changing a day won't do much and I should go up to 5mg which I didn't really want to do.. also don't want to waste money on 2.5 and it's clearly doing not a lot

I agree that your dosing day is a problem for you. What is more important to you currently, losing the weight or eating and drinking very well at the weekend? I say very well, because it undoes the loss during the weekdays.

Or, weigh on a Thursday, or more frequently than weekly. Then you can see your progress.

Also, it's been a heatwave in most places, so you could simply be retaining water. Or it could be from your menstrual cycle.

Either way, I'd change up the days for injecting and weighing. You can always take only 30 clicks from the new pen if you want to stay at 2.5mg for now, or choose a dose somewhere in-between.

Wouldn't it be worth considering cutting down or cutting out the alcohol, as well as focussing on keeping calories lower at the weekend before you decide to go up a dose? If you can manage those two things on 2.5mg then you don't need to go up just yet.

But, you say that 2.5mg "isn't doing a lot"? Yet you say you're ok during the week? It's normal for suppression to be lower on day 6 and 7, so changing when you inject to Friday may well help sort the weekends out.

Well tbh if you jab on Monday so you can eat and drink what you want at the weekend you’re just undoing the point of the jab which is to make you eat and drink less and therefore lose weight. It may be that your weekends are what is causing you to retain or gain weight.

Go up to 5mg. And I’d start jabbing on a Thursday.

I used to jab on a Saturday and weigh on Saturday but moved jab day to Monday when went away and for past 5 months jab on Monday and weigh on Saturday I think as long as I’m consistent the numbers are kept in line

If you are taking mounjaro to loose weight why are you then using it in such a way that you can maximise your calorie intake on the weekend?
You need to decide what you want, and take things seriously, inject on Thursday, watch what you eat and drink over the weekend, if that doesn't help you lose weight THEN increase to 5mg.

OR

Stop taking mounjaro.

This. You really need to sort your weekends out and moving your jab day would help.

Increase to 5mg
Inject mid week/Thursday
Adjust your attitude to weekends and to seeing food and alcohol as treat and reward (this takes a bit of time, but the injection helps as it makes it less appealing)
Over time you will find the effect lasts the whole week rather than disappearing by day 5 but for now you need to deal with your weekends by injecting later in the week.

You need to increase your dose when you finish the pen. It works differently for different people and some don't lose until in higher doses.

When it's working you won't want or be able to loosen up at weekends. I used to just have a starter when I went out.

You lose the weight by consuming less calories. Mounjaro helps you do this.

If you only have 2 stone to lose your daily calorie requirements to maintain your weight won’t be that high. Work out your TDEE. To lose one pound per week you need to eat an average of 500 cals per day LESS. It’s hard. If you eat in deficit Mon-Thu but consume more at weekends you won’t lose weight. You need a consistent deficit over the whole week.

Paying for Mounjaro and then eating and drinking at weekends makes no sense to me.

Sure try moving injection day if you want. My highest suppression is days 3 4 5.

I weigh most days and take an average over the week as my weight fluctuates depending on weather, travel and carb consumption.

I would go up to 5, adjust your attitude to weekends and prioritise losing the weight. Continuing on 2.5 when you aren’t losing weight is a waste of time and money.

Not necessarily true. I lost 22kg and ate 2-3 full meals every day for the duration of my weight loss. Even at 7.5mg I could eat a whole pizza if I wanted to. I lost weight because I would naturally then adjust my intake in other meals and never snacked on anything but fruit.

I jab Friday mornings specifically so I don’t undo all my efforts from the week!
With only 2st to lose it will take longer generally than someone who starts with 5st to lose. I weighed daily for the first 8 months so I could understand my fluctuations due to my cycle and impacts of certain choices - for example if I have alcohol I will not lose any weight for the next 3 days and often will show a “gain”

This is a mental issue you need to tackle. You already set yourself up on a dodgy path by deciding to jab on a Monday specifically so you could enjoy your weekends. If you want to lose weight you need to be in a consistent routine and calorie deficit. It won’t work if you just do it 5 days a week. Mentally you decided eating/alcohol at the weekend was more important than weight loss longer term. Thats the real issue, not how what dose you take.

Thanks for the advice I have decided to go up to 5mg and I will be changing my jab day .. but just to be clear when I say I eat more and drink on weekends i mean compared to the week but I am still calorie counting and in a deficit even on weekends .. I have been doing calorie counting for two years using nutracheck i used to weigh on a Saturday and have Saturday as my cheat day and get straight back on it Sunday I did this from the very start this worked for me and I lost 3 stone but needed to jab as it became stagnant .. I have been doing the same whilst on the jab but still eating and drinking less even on the Saturday as I do get full quick and when I say drink I literally mean a few drinks . I have cut out snacking completly even on weekends so I am disappointed at my loss

and tbh no I refuse to be miserable and never be able to enjoy myself and socialise and go for meals out at the weekend after working all week for the sake of two stone so if that is what the jab does then I won't continue to take it

i had a consultation today and they do not think it is anything to do with the jab day and advised me to go up a dose

I think both. Go up a dose and jab on Thursday

Good luck with it, hope it works out for you.

If I drank alcohol at all whilst losing, the effect was I didn't basically,I'd have a couple of drinks and maybe a couple of potatoes with dinner at the weekend,and up the scales would go,up so I stopped drinking altogether started weighing every day 16/ 8 and the pounds came off, even on a small dose. It was slower as the numbers went down , but they went down consistently, I actually never really wanted a drink while on it much, I can drop back down really easily now if I go up by cutting out alcohol, your body prioritises dealing with the alcohol,hangs on to water and stores it , mounjaro does help with this but not entirely , I think if you are determined to keep your weekends as you are you will be disappointed, moving up to 5 was horrendous for me too absolutely spewed my guts up and just about slept for a week, only took it once,came back down to 2.5 for the rest and lost nearly six stone, would stay on it forever but it's too expensive, keeping it off without but it's harder.

You have demonstrated why I said it’s a mental issue you need to tackle: reframe it in your mind.

You do not have to be ‘miserable’ at all, never mind just at weekends but you have set yourself up to fail by viewing it like that.

You’re essentially “dieting” for 5 days a week and then not sticking to those rules for 2 days.

Thats not what mounjaro is for - it’s a whole lifestyle change

I agree. I am not miserable, I still socialise and still go out for meals. I even have a small glass of wine a couple of times a week but I've never really been someone who needs alcohol to enjoy a social event. Now I am learning that I also don't need lots of food to have a good time. It's all about changing perceptions for the long term good.

Well yes, of course that’s what the jab does, it suppresses appetite and that’s how you lose weight. I didn’t find it miserable to eat/drink less on the jab because the jab meant I didnt want to eat/drink much. You can still go out but just have a lower cal meal and some soda water to drink.

If you have been calorie counting you may have misjudged your maintenance calories if you’re still not losing weight. Unless you have certain very rare diseases or are on other medication then you will lose weight if you are in an energy deficit.

A few alcoholic drinks could very well be ruining your loss - 3 glasses of wine can be 500+ calories and 3 beers can be 600+. Alcohol also doesn’t stop GLP‑1 medications from working, but it often stops weight loss because drinking adds liquid calories, lowers inhibition around food, disrupts sleep, causes blood sugar dips that trigger carb cravings, and temporarily slows fat burning while the body clears the alcohol; together these effects can wipe out the calorie deficit GLP‑1s create, making it feel like the medication isn’t working even though the drug itself is still active.

If you're not losing weight then you're not in calorie deficit every day. Either you're miscounting or you're overestimating your TDEE.
I personally inject on a Friday morning, but I must say it in no way prevents me from enjoying the weekend, from either a food or a drink perspective. On the contrary, I still go out and enjoy meals on a regular basis. The great benefit of Mounjaro is it allows me to enjoy those meals (and a drink) but it allows me to exercise portion control at the same time.
I recommend you switch your injection day to late in the week. I wouldn't be in too much of a rush to move up to 5mg necessarily.

I’m on Wegovy at 0.25 through my medical service. I had a bit of up and down at the start too. I just use the app tracking and the occasional clinician check-in if I’m unsure about anything. It’s helped me stay a bit more relaxed about the small fluctuations.