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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

April 26 Mounjaro Weight Loss Starters. (title edited by MNHQ at request of the OP)

544 replies

TFICoffeetime · 30/03/2026 14:49

Hi starting mounjaro this week is there a thread already set up I can join?

OP posts:
anchoviesanchovies · 23/04/2026 11:06

Z0rr0 · 23/04/2026 11:02

Thanks @NorthDevonBeachLover. You’re right I know, was just a bummer. Really wanted a little bit more this week. @anchoviesanchovies I think some people are squeezing a 5th dose out of their pen. 🤷‍♀️

Ah ok, thanks.

SilenceInside · 23/04/2026 11:09

I hope you don’t mind me jumping on your thread to answer questions about the “golden dose”…

There will be between 0.6 and 0.9ml of medication left in the pen after doing the normal 4 doses. A full dose from the pen is 0.6ml. So people access that leftover medication to use as a fifth dose from the pen.

The pen mechanism locks after doing 4 normal doses. You can force the pen to turn again by twisting the end hard, sometimes needing pliers, to break the internal mechanism. You can then do another dose as before, using a new needle. If your supplier hasn’t sent you more than 4 needles then you need to buy some more eg from an online pharmacy.

The other approach is to use a separate 1ml syringe with a fixed needle to extract the medication via the red seal, and then inject using that separate syringe. If you do that, you can use more than 0.6ml and increase the dose.

thinkofsomethingdifferent · 23/04/2026 12:02

@NorthDevonBeachLoverim not sure. Pre MJ id have the curry, rice, chips and garlic bread. Yesterday I had no chips and half a garlic bread. What I do know is I’ll be in calorie deficit today as I won’t be eating a thing. I’m due to go up to 5mg on Monday and now I’m concerned. Perhaps the whole curry rather than just half was simply too much. I did enjoy it though 🤣

thinkofsomethingdifferent · 23/04/2026 12:03

@Z0rr0my 2.5 pen came with 6 sharps so I just snapped the mechanism with my teeth and used a spare needle to extract.

custardlover · 23/04/2026 12:54

Hmm, week 2, day 6 (eg going to jab tomorrow) and I am feeling quite hungry today. It’s not driving me to go mad snacking but I absolutely could whereas up until now it really didn’t even think of it!

Thepinkwave · 23/04/2026 13:11

custardlover · 23/04/2026 12:54

Hmm, week 2, day 6 (eg going to jab tomorrow) and I am feeling quite hungry today. It’s not driving me to go mad snacking but I absolutely could whereas up until now it really didn’t even think of it!

It was exactly like me yesterday when I was on week 2 day 6. I injected third dose this morning and food noise is already gone. I wonder if it is a placebo effect ahah

EducatingEater · 23/04/2026 13:21

I have ordered the 5mg pen from medexpress over pharmica who I went with first time for 2.5mg to move up in about 10 days. Weirdly it was easier than the pharmica ordering and was accepted first time, however I assume that was because I provided evidence i had had it before so wasn't quite as "thorough" (didn't need the video on the scales etc, just a screen print of the previous order with the date and my details and a full length picture with what I weighed when I started and the weight I am now.

I ordered a bit ahead because I didn't want a delay and was aware how long pharmica had taken to issue the first pen so covered my back. It helped that I ordered it in March but didn't start until 8th April too.

So far, approaching weigh in three/jab 4 on Monday I'm finding no real issues of side effects, I'm tired but then I always am, especially with so much weight to carry around, the struggling with exercise and mobility isn't a new thing too and I'm hoping will continue to improve there so I can start walking more. There's definitely suppression happening, appetite is lowered, but not completely gone. I do get hungry at the right times. The food noise is still there, though reduced, as I often want to have something else in the evening and think I'm hungry when I'm not.

I urgently need a doctor's appointment with regards to other stuff going on, but I keep delaying this due to not having faith in my doctor during covid due to lots of things that happened. Even though I know he's not there anymore and it's a different doctor, I'm still struggling getting over the door to go in. I will do it, before we get to May providing he can see me before then (I am going to ask for a double appt so might be trickier. At least hopefully it will be booked by then).

Hope everyone is doing as well as they possibly can be ❤️

22sra · 23/04/2026 14:56

Is anyone else due to start late April? My pen arrived yesterday so will be taking my first jab on Sunday evening. Is anyone else on early jabs or just starting? Or should I wait to join the May thread?

didldidi · 23/04/2026 16:09

NorthDevonBeachLover · 23/04/2026 09:02

Week 3 weigh in and I'm down a total of 10lb now. Thinking I might do another month of 2.5 as happy to lose it slowly.
@didldidi how are you this week? x

Hello! Another 2lbs for me so 9 in total. Just received my 2nd 2.5mg pen yesterday but am going to try the 5th dose first!

Nugg · 23/04/2026 18:19

@22srai did my first on Tuesday evening. No change in any way so far!

Isabelle70 · 23/04/2026 21:27

I did my first jab this afternoon with the nurse, it was much easier than I expected.

22sra · 23/04/2026 21:39

Ahh I’m desperate to start! Birthday weekend though so thought it best to wait until Sunday in case of side effects.

likewhatyoudo · 24/04/2026 00:15

Question -- how did you order your second pen? Was it simple?
I ordered my first with Pharmulous. Do I have to go through everything all over again? Don't they have my details on file. I couldn't find any buttons for existing customers etc. I'd like to order a 5mg this time. I'm losing some weight through restricted calories, but it's harder than the first week. I feel hungry and need a bit more help.

likewhatyoudo · 24/04/2026 00:21

Z0rr0 · 23/04/2026 11:03

Also with the golden dose, how do you take that without a sharp? Or do you leave the last sharp on from dose 4?

no, don't reuse a sharp. Buy some spares. They're widely available.

SilenceInside has some tips a few posts on from your post (above)

Nugg · 24/04/2026 06:43

Can I everyone how soon you felt any effect at all please? I’m only on week one but literally no side effects or appetite suppressant but only jabbed on Tuesday evening.

Ilovepeas175 · 24/04/2026 07:09

This is Wk3 for me, took my 3rd jab on Tuesday. Lost 9lbs over the first 2 weeks, had some mild side effects like headaches & nausea. Yesterday (Wk 3 day 2), had the worst headache yet & felt so sick all day. Couldn’t really eat anything. I have ordered and received my 2nd pen and glad I’ve stuck at 2.5mg 😷

RosieSpring · 24/04/2026 08:20

Hi all,
So I ended up starting on Tuesday morn, did the injection at 6am, by the evening I wasn't hungry at all which was great at the evening time is my binge time with food. Have had small dinners since and feeling OK, a little tired and I think there's a good bit of willpower involved too. One thing annoying me is that I'm not thinking of eating food but I can't stop thinking of not eating food or the monjaro! Anyone else?

pomegranatepie · 24/04/2026 08:33

Nugg · 24/04/2026 06:43

Can I everyone how soon you felt any effect at all please? I’m only on week one but literally no side effects or appetite suppressant but only jabbed on Tuesday evening.

I think this really varies for everyone, some need a higher dose to feel the effects, some have effects straight away. I did my first jab on a Sunday night and had zero interest in food the next morning, made myself eat at regular meal times, and only managed to eat small portions, by the end of the week I was feeling a little hungry again at times, but still only managed small portions. But it's really individual, and it builds up in your system over weeks.

pomegranatepie · 24/04/2026 08:36

RosieSpring · 24/04/2026 08:20

Hi all,
So I ended up starting on Tuesday morn, did the injection at 6am, by the evening I wasn't hungry at all which was great at the evening time is my binge time with food. Have had small dinners since and feeling OK, a little tired and I think there's a good bit of willpower involved too. One thing annoying me is that I'm not thinking of eating food but I can't stop thinking of not eating food or the monjaro! Anyone else?

I have this a little too, I think some of it is habitual thinking though, as I have been trying to lose weight one way or another for decades (yo yo dieting), and it's difficult to switch this off. I am definitely thinking about it a bit less this week though, and really enjoyed the extra space my brain has to concentrate on other things now the background food noise has gone.

NorthDevonBeachLover · 24/04/2026 08:44

RosieSpring · 24/04/2026 08:20

Hi all,
So I ended up starting on Tuesday morn, did the injection at 6am, by the evening I wasn't hungry at all which was great at the evening time is my binge time with food. Have had small dinners since and feeling OK, a little tired and I think there's a good bit of willpower involved too. One thing annoying me is that I'm not thinking of eating food but I can't stop thinking of not eating food or the monjaro! Anyone else?

Totally get this, I have a supressed appetite but I keep thinking about eating still, trying to plan protein etc, I think It's because I've constantly thought about food all day every day for so many years!

NorthDevonBeachLover · 24/04/2026 09:47

didldidi · 23/04/2026 16:09

Hello! Another 2lbs for me so 9 in total. Just received my 2nd 2.5mg pen yesterday but am going to try the 5th dose first!

I also have some left in the pen which I'm hoping to extract. Will the needles supplied fit on the end of a 1ml syringe? I've only got 1 x needle left so need some more, what is recommended to use?

ScreamingDelight · 24/04/2026 10:42

2nd weigh in today and 2lbs off. I took my 3rd jag on Wednesday but weigh day is friday for me. I have ordered a 5mg pen for next month but im not sure if i will maybe just take 2.5mg, i felt food noise was creeping back, but is this something we are going to need to manage long term anyway

custardlover · 24/04/2026 10:48

So second weigh in today and third jab and I have lost 6kg or basically a stone in a fortnight! I am stunned.

Just jabbed again and feeling slightly light headed but otherwise all good.

SilenceInside · 24/04/2026 11:07

@NorthDevonBeachLover The pen needles only fit on the pens. If you buy separate 1ml syringes, they can either come with fixed needles, or you can get a type of syringe called Luer Lock syringes where you can attach and remove Luer Lock compatible needles. The needles you need for the Luer Lock syringes are different to the pen needles. You don't really need Luer Lock syringes and needles to extract the leftover medication, a fixed needle is fine.

These sorts of 1ml syringes have a fixed 8mm needle, for example:

https://ukmedi.co.uk/products/fms-micro-syringe-32g-8mm-1ml-fms-fms-32g-10ml-ukmedi-co-uk

You want a gauge of 30 or 32g, which is the same as the pen needle gauge. A length of 4 to 8mm is standard for a subcutaneous injection.

Nugg · 24/04/2026 12:21

@pomegranatepiethank you! Still eating normally which isn’t bad at all but the food noise is real and there still. Strange!

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