Came off MJ and the sodding planter fasciitis is back.

[DontKillSteve]

Been off MJ a couple of months now. Was on it for 10 months. Weight is steady BMI 20. The frigging plantar fasciitis (which completely went away) is back with a vengeance. I thought it was weight related but clearly the Mounjaro was having a direct effect. Tempted to go back on it.

Why did you come off Mounjaro so soon?
The usual recommendation is to stay on MJ for at least a year after reaching your goal weight and let your body adapt and get used to the changes.

That is both interesting and (selfishly) concerning @DontKillSteve . Within a month of starting Mounjaro my long term hot ankle swelling and pain (I used to hobble down the stairs one at a time in the mornings gripping the banisters like a frail old lady - I’ was only 55) disappeared. It does worry me sometimes it may return when I stop.

Mounjaro was/is likely helping with the inflammation and masking the symptoms for both of us, but ideally, if my problems return and now obesity can no longer be blamed I will want to try to get to the root cause rather than continue masking symptoms. I have only started maintaining recently so a while before I try to come off, but thanks for sharing your experience, I will be considering it in my plans.

Do let us know how you decide to proceed and progress . Good luck 🍀

I don’t think it masks symptoms - I think it actually switches off the production of pro-inflammatory proteins, there is a lot of research going on, and I think they are looking at developing MJ in tablet form. I am also hopeful that within the next 10 years, maybe MJ tablets will be available via the rheumatologist, for treating autoimmune and inflammatory conditions. I honestly think it is a wonder drug. I am planning to never come off it (and will probably try titrating right down as far as I can go , when it comes to permanent maintenance. I have major problems with inflammation in my spine, spinal muscles, and other joints, and within just 3 days of starting on the lowest dose last year, it had switched off. I have found that these positive effects have disappeared at the higher doses, so I have titrated back down to 10 mg this month. I have a relative with autoimmune things going on, and they are on really major meds to try and control it, the side effects of which can be dreadful - but MJ seems so much easier.

Have you tried rolling a tennis ball under your foot? I did it as many times as I could stand and it’s completely cured my PF.

Omg I never even considered this - but I too used to hobble down the stairs first thing in the morning feeling like an old lady! Also had PF on occasion - usually whenever I attempted to take up running.
I was just thinking the other day how I can skip downstairs so easily in the morning, and assumed it was the nearly 5 stone weight loss - but of course MJ reduces inflammation as well, doesn't it.
Tbh though, I've pretty much decided I'll be on some sort of maintenance dose of MJ for life now.

Wow, this interesting. I was suffering terribly before MJ but had shockwave therapy a month after starting. Now I wont actually know if that helped or the MJ. I am staying on the jabs for a while on maintenance so will see what happens after.

I was still dropping weight taking 2.5 every 2-3 weeks and starting to look a bit underweight. I was quite sensitive to it even at low dose.

Thanks all. I’ll see how it goes. It took a while to return after I stopped. Really annoying.

Could you try micro dosing? I know very little about it other than it being a thing.

My GP was saying that the benefits of MJ on autoimmune conditions are becoming more well known (I have one too)and that I might benefit from staying on MJ longer term after I’ve reached my goal weight.

In your case, it might still be worth trying micro-dosing on 1mg rather than stretching out the dose to every 3 weeks and see if that makes a difference?

Yep - my chronic PF disappeared within the first week of taking Mounjaro, when my BMI was still 43! So I know it was the Mounjaro, not the weight loss.

14 months later, I'm heading towards my goal weight, but will then taper down as much as I can and hopefully stay on something between 1.25 - 2.5mg, just to keep the PF (and IBS, which it also got rid of) at bay.

Can you try 1.25mg every 10 - 14 days, maybe, just to help with the inflammation?

And fingers crossed for tablet form, cheaper MJ in the future...!

I found this when I stopped. Mounjaro was reducing the inflammation for my advanced arthritis.
It helped me more than any of the mountain of drugs prescribed by the NHS over the years.

I’d have to change prescriber to micro dose. I was with Morrisons and they were very keen for me to come off once I reached goal weight. At one point I was taking 3.75mg which they didn’t approve of.

It’s a shame that the NHS isn’t fully supportive of the benefits of MJ on inflammatory and auto immune conditions etc. Surely, this will save them money longer term instead of offering say, inaffective large dose steroid drugs?

My Irish GP is keen for me go stay on MJ after losing the weight and thankfully, will write out my prescription. I still pay privately for the drugs but at least the Pharmacy will adhere to the prescription without questioning it so I know I’ll be able to continue to buy it without any issues.

Has anyone experienced relief from endo pain on MJ?

I switched from MJ to Wegovy with the price increases months back.

My neck, upper back and left knee have returned with their aching and stiffness.

Incredible to be reading this.
I can’t afford MJ anymore. Gutting.

This is super interesting. My PF also went after starting mounjaro but I didn’t monitor when it stopped hurting, but like others assumed it was because of the weight loss. However, I’ve recently started 15mg and found it a little sore in the mornings again, only a tiny amount but still noticeable. Odd

I have hip problems and asked at the GP if I cold get weight loss drugs because on the forums I’m on people swear it’s eliminated their pain. They wouldn’t let me as I’m not overweight (fair enough) but I have heard of that being a thing.

Ok so I took a dose and in a few days it’s all subsided again. There’s the proof then.

I did the same. Within a couple of days of restarting mounjaro the pain had decreased again.

It is definitely the mounjaro which helps my arthritis, not the weight loss.

It also helps my colitis which I have as a permanent side effect of cancer treatment.

I heard a thing on the radio yesterday - they're trialling WLI (wegovy not MJ) on obese patients with heart disease.

They said trials showed improvements in heart health quickly, and long before v much weight loss - suggesting it is the drug itself, rather than the weight loss which causes the improvements.

V interesting.

I’m really glad it’s helped you but it’s ridiculous that you can’t get it prescribed on the NHS when it’s clearly beneficial to your physical health. So many posters reporting how MJ helps with inflammation and auto-immune issues too.

Maybe things will change when the tablet form comes out? 🤞

I found that too. I had bought a 15mg pen, and all of my (massively debilitating) symptoms came back. Mine was one of the older pens (I think they are phasing these out), with the ‘golden dose’ - so I googled how many clicks of it equates to 10 mg, so I just titrated down that way, and symptoms went after a few days back at 10mg. For me, the symptoms are completely debilitating - I get inflammation in my spine, which spreads to the muscles surrounding, and reduces my qual of life massively - so for me now, the WLI are primarily for symptom relief, and only secondarily for weight loss (I still have a lot of weight to lose, so it will be a much slower journey.
Coincidentally, I have also seen medical research articles that have found the benefits (re inflammation) are only there up to 10mg doses - i dont think they were able to explain why though, unfortunately.

That’s very interesting- thanks for sharing your experience. I knew my psoriasis and asthma disappeared overnight but I just didn’t make the connections with my PF

I’m finding this thread fascinating, thanks very much all!
I have got Mounjaro waiting in the fridge for me to start taking in a week or so after I come back from holiday and I am now very much looking forward to it reducing my aches and pains as well as helping me lose weight.
I’m very stiff in the mornings and after I’ve been sitting down for a while, have had PF and ibs on and off and I’m looking forward to getting more mobile again.