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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Back on it after 3 months off and weight gain

43 replies

Christmashope19 · 01/02/2026 10:25

That’s me started 2.5mg yesterday
I got into my healthy bmi range (just) back in October
I came off Mounjaro and have not been making healthy food choices, totally my own fault and have been putting weight back on
In the 3 month period I have put on 18lbs which I’m disgusted with
never mind I feel like I’m in the right frame of mind now to go forwards
Anyone else on their second journey with Mounjaro?

OP posts:
notcomfortable · 01/02/2026 10:26

Me! I gained 10kg back
But I'm about to come off again, for personal reasons

Mysticmaiden · 01/02/2026 10:50

OP did you eat a lot more as well as unhealthy food choices and what was your activity/exercise like? I ask because I'm tapering down and maintenaining but hoping to come off in 4-5 months time if jot before but I was mildly diabetic, had high BP and cholesterol so have health concerns as well as concerns for increased appetite and serious carb cravings, which I used to have when I was prediabetic and diabetic. I've switched to wegovy 2.5 months ago and the carb and junk food cravings have returned so I'm going back to mj after the next 2 doses because I feel I need that extra blood sugar control of mj.

Disturbia81 · 01/02/2026 10:58

Thanks for posting OP it’s helpful for others to see that weight goes back on easily when you come off it unless lifestyle overhauled.

Christmashope19 · 01/02/2026 11:41

Mysticmaiden · 01/02/2026 10:50

OP did you eat a lot more as well as unhealthy food choices and what was your activity/exercise like? I ask because I'm tapering down and maintenaining but hoping to come off in 4-5 months time if jot before but I was mildly diabetic, had high BP and cholesterol so have health concerns as well as concerns for increased appetite and serious carb cravings, which I used to have when I was prediabetic and diabetic. I've switched to wegovy 2.5 months ago and the carb and junk food cravings have returned so I'm going back to mj after the next 2 doses because I feel I need that extra blood sugar control of mj.

Edited

Yes I did
I actually gorged on food some days I’m not going to lie then I used to feel awful
I have also found it really difficult to get out and walk as much due to the weather which has not helped
I can’t make excuses however I did feel hungrier than normal when I stopped mounjaro
x

OP posts:
Christmashope19 · 01/02/2026 11:42

Disturbia81 · 01/02/2026 10:58

Thanks for posting OP it’s helpful for others to see that weight goes back on easily when you come off it unless lifestyle overhauled.

Exactly this!

OP posts:
Christmashope19 · 01/02/2026 11:42

It’s frustrating isn’t it

OP posts:
soupyspoon · 01/02/2026 11:44

Were you tracking and calorie counting? You cant guess what your intake is, you have to calculate it to be sure, even if you go over, otherwise its a shot in the dark as to whether you'll maintain

Also ensure that you come off it slowly rather than just stop.

Notsosweetcaroline · 01/02/2026 12:33

Christmashope19 · 01/02/2026 11:41

Yes I did
I actually gorged on food some days I’m not going to lie then I used to feel awful
I have also found it really difficult to get out and walk as much due to the weather which has not helped
I can’t make excuses however I did feel hungrier than normal when I stopped mounjaro
x

From what I understand it’s normal hunger you’re just not used to it so it feels more intense. Plus you’ve nothing controlling your blood sugar so you get the highs and lows again, causing cravings. The drugs don’t change us permanently, it’s simply they don’t work when you don’t take them, so go back to normal, but as you’ve not felt it for some time, it feels more intense.

onlyhereforthechaletschool · 01/02/2026 14:04

I was on MJ for diabetes from Sep 24 to Oct 25. Then the dr withdrew it as my blood sugar was under control! I’d never gone beyond 5mg, and to be honest didn’t lose much if any weight from April 25 onwards - or I gained and lost the same kg! I’d gone down from a BMI of about 42 to 30 but obviously there was still some way to go.

After 3 weeks off it I decided to self fund (as the kg had become 2) … the pharmacy made me start back on 2.5mg and I couldn’t believe after just 3 weeks I could feel supression again on a lower dose.

I did 4 weeks on 2.5 and 4 on 5mg where I lost a small amount in that time … went up to 7.5mg 2 weeks ago and slightly regret it - side effects this week haven’t been nice … hoping they’ll get better …

SilenceInside · 01/02/2026 14:15

@Disturbia81 did you find that you felt that you were hungrier than before taking Mounjaro when you stopped taking it? Did you find that you gained weight quickly?

ShawnaMacallister · 01/02/2026 14:23

Notsosweetcaroline · 01/02/2026 12:33

From what I understand it’s normal hunger you’re just not used to it so it feels more intense. Plus you’ve nothing controlling your blood sugar so you get the highs and lows again, causing cravings. The drugs don’t change us permanently, it’s simply they don’t work when you don’t take them, so go back to normal, but as you’ve not felt it for some time, it feels more intense.

Studies suggest it's NOT normal hunger but is elevated compared to pre WLI levels. Elevated hunger can last up to 12 months after stopping and isn't entirely managed by tapering down though that is likely to help.

soupyspoon · 01/02/2026 14:25

ShawnaMacallister · 01/02/2026 14:23

Studies suggest it's NOT normal hunger but is elevated compared to pre WLI levels. Elevated hunger can last up to 12 months after stopping and isn't entirely managed by tapering down though that is likely to help.

How does one study something so subjective?

Its based on self reporting yes?

So I say Im starving and much more starving than pre jabs. How is that objectively measured. Of course I think Im starving much more, Ive forgotten how much I used to eat and how much my cravings were, it comes back as a shock.

Disturbia81 · 01/02/2026 15:06

Notsosweetcaroline · 01/02/2026 12:33

From what I understand it’s normal hunger you’re just not used to it so it feels more intense. Plus you’ve nothing controlling your blood sugar so you get the highs and lows again, causing cravings. The drugs don’t change us permanently, it’s simply they don’t work when you don’t take them, so go back to normal, but as you’ve not felt it for some time, it feels more intense.

The end result is the same though.

Disturbia81 · 01/02/2026 15:06

SilenceInside · 01/02/2026 14:15

@Disturbia81 did you find that you felt that you were hungrier than before taking Mounjaro when you stopped taking it? Did you find that you gained weight quickly?

Think you quoted the wrong person

SilenceInside · 01/02/2026 15:10

@Disturbia81 no, I was asking you about your experience of hunger when you came of Mounjaro. You said that the weight went back on easily when you came off, in your post at 10.58 today. Unless that’s not what you meant?

Disturbia81 · 01/02/2026 15:21

SilenceInside · 01/02/2026 15:10

@Disturbia81 no, I was asking you about your experience of hunger when you came of Mounjaro. You said that the weight went back on easily when you came off, in your post at 10.58 today. Unless that’s not what you meant?

No you have misread.

momager22 · 01/02/2026 15:34

Hi @Mysticmaidenwhat counts as ‘mildly diabetic’ ?

SilenceInside · 01/02/2026 15:36

Just wondering what your own experience was with Mounjaro, @Disturbia81?

Winter2020 · 01/02/2026 15:43

I feel (intuitively without evidence) that if you come off Mounjaro after say losing 3 stone in 3 months your body will know it is starving and your hunger/food drive will be very strong. I think this because that would be the case if someone had lost that weight not on Mounjaro. However I think if someone comes off Mounjaro after maintaining on it for a year or so after their loss their body would not be starving so their hunger would be much more manageable - especially if they supported their appetite with lots of protein and fibre. Thats just my guess.

Notsosweetcaroline · 01/02/2026 15:49

ShawnaMacallister · 01/02/2026 14:23

Studies suggest it's NOT normal hunger but is elevated compared to pre WLI levels. Elevated hunger can last up to 12 months after stopping and isn't entirely managed by tapering down though that is likely to help.

What studies, I think you need to link to that as It looks like nonsense to me.

@Disturbia81 I recognise your user name , you’ve never been in weight loss injections is that correct, are against them and are all over these threads giving people advise on them? Looking at your posting history this seems correct. So why didn’t you just tell the poster asking you’d never taken them and have no idea?

Disturbia81 · 01/02/2026 15:57

Notsosweetcaroline · 01/02/2026 15:49

What studies, I think you need to link to that as It looks like nonsense to me.

@Disturbia81 I recognise your user name , you’ve never been in weight loss injections is that correct, are against them and are all over these threads giving people advise on them? Looking at your posting history this seems correct. So why didn’t you just tell the poster asking you’d never taken them and have no idea?

I’m not against them at all, read my posting history. They are a brilliant medication. I said weight will go back on unless lifestyle changes made, which of course it will like any diet. But people I’ve known who come off and start eating what they want again put weight on.
I don’t get how anyone can argue with that or have a problem? Unless you feel the need to defend WLI at all costs including making out that people won’t put weight on even if they don’t change habits?

Notsosweetcaroline · 01/02/2026 16:02

Disturbia81 · 01/02/2026 15:57

I’m not against them at all, read my posting history. They are a brilliant medication. I said weight will go back on unless lifestyle changes made, which of course it will like any diet. But people I’ve known who come off and start eating what they want again put weight on.
I don’t get how anyone can argue with that or have a problem? Unless you feel the need to defend WLI at all costs including making out that people won’t put weight on even if they don’t change habits?

No one is arguing that, but it’s right you’ve never taken them?

autumnboys · 01/02/2026 16:40

This thread seems to have unraveled a bit….

i took MJ for 6 months Aug 24 to Feb 25 and had to stop cold turkey. I had just gone up to 7.5 and I’d lost just over 25kg.

I maintained my loss from Feb to December with the odd fluctuation due to hormones and holidays. I counted calories, exercised a lot and struggled with food noise every single day. I got too cocky over December, let the brakes come off and just could not get them back on. I’ve gained about 5/6kg, so not disastrous but I couldn’t rein it in.

Started MJ again on Thursday after my GP cleared me.

soupyspoon · 01/02/2026 16:52

Winter2020 · 01/02/2026 15:43

I feel (intuitively without evidence) that if you come off Mounjaro after say losing 3 stone in 3 months your body will know it is starving and your hunger/food drive will be very strong. I think this because that would be the case if someone had lost that weight not on Mounjaro. However I think if someone comes off Mounjaro after maintaining on it for a year or so after their loss their body would not be starving so their hunger would be much more manageable - especially if they supported their appetite with lots of protein and fibre. Thats just my guess.

Yes thats a good point, intuitively that seems right

Notsosweetcaroline · 01/02/2026 17:00

Winter2020 · 01/02/2026 15:43

I feel (intuitively without evidence) that if you come off Mounjaro after say losing 3 stone in 3 months your body will know it is starving and your hunger/food drive will be very strong. I think this because that would be the case if someone had lost that weight not on Mounjaro. However I think if someone comes off Mounjaro after maintaining on it for a year or so after their loss their body would not be starving so their hunger would be much more manageable - especially if they supported their appetite with lots of protein and fibre. Thats just my guess.

I also think there is something in this and it’s why it’s absolutely critical to do this in a healthy manner of up to 2lbs a week. Then you’re not starving and it’s like any other diet when you stop. But if you move into 3lbs a week or more, which is a 1500 calorie a day deficit then I you will be starving when you come off.

im not sure the maintaining for a year is as big a deal as losing the weight in a healthy manner, but if your body adjusts to maintenance cals for an extended period then reducing and coming off would be even easier.

so yes, I think I also agree with you.