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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

What happens when people stop the injections?

162 replies

IndigoBluey · 30/11/2025 01:18

Just this really, when you reach your desired weight following the course of weight loss injections, do you stop taking the injections whilst sticking to a much healthier way of eating? I’m genuinely curious as to how it works in the long term. A friend of mine had stomach surgery a few years ago to shrink her stomach and very rapidly went from 18 to 9 stone, but then put a lot of weight back on gradually, to then start on WL injections. I suppose my question is when you know you are finished with needed the injections?

OP posts:
TheRealGoose · 02/12/2025 17:31

JacknDiane · 02/12/2025 16:21

That's brilliant. That's what I hope I would do. But I dont trust myself. Im an emotional eater. I need to loose 3 stone but im scared to try mounjaro, get slim, feel absolutely brilliant, then slowly slip back to my old eating habits. And I have no confidence I wouldn't.

Is that Really worse for you than staying fat?

KilliMonjaro · 02/12/2025 17:52

andforthefirsttimeinforever · 02/12/2025 16:22

Why not lose the weight first and then address the rest? That’s what I’m doing Smile

This!

KilliMonjaro · 02/12/2025 17:54

Tohaveandtohold · 02/12/2025 13:09

I’ve not read the full thread but just my experience. I was on the Jab for just over 4 months, 4 pens, I lost over 3 stone and I’ve been off the Jab now for almost 10 months. I’ve gone on to lose almost another stone in the time that I’ve been off the jab.
I eat well and clean. I never used to exercise but I’ve been consistently exercising, mostly weights training 5 days a week for almost 1.5 years now. The only week I didn’t was when on holiday. I love exercise now, it’s routine for me. Eating well and right is my goal, I don’t even feel like I’m dieting because I snack but rather than snacking on tons of chocolate like I used to, I snack on fruits , veg, protein, etc and if I have to eat a chocolate, I eat one rather than a whole packet. I’ve changed my mindset and I’m in a so much happier place.
I pray I don’t see anything that’ll make me not want to exercise cos I enjoy it and it’s given me so much freedom in my maintenance journey cos I know without it, I would be more obsessed with my food, etc than I am which is not a place I want to be. That’s my own experience. My home life and circumstances mean maintenance without the jab is working much more better than I was expecting

Brilliant!

Soulstirring · 02/12/2025 19:11

I was on mj and slowly put weight back on when I stoppped 9 months ago. I’ve put about a kg a month on. But due to work etc I’m a lot less active now too. I have just restarted on wegovy due to cost. I need the food silence and the aversion to alcohol.

IndigoBluey · 02/12/2025 23:54

Some very insightful responses. To those questioning my curiosity, I can’t really explain anymore than I have done already. I’m genuinely curious as to the long term, sustainable goal. I know how hard weight loss is and that my journey is nowhere near as hard as many of you.

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IndigoBluey · 03/12/2025 00:01

andforthefirsttimeinforever · 02/12/2025 06:09

So there is palpable glee when someone who has been obese loses weight then gains it again. Better?

Or - someone very big indeed who loses weight then gains it again has barely concealed delight from some friends.

Which do you prefer?

Give it a rest now. You are using multiple threads to stoke a fire that you are trying to start. I hope no one on this thread is gleeful or delighted about weight loss and subsequent gain. It sounds like a main focal point of yours.

OP posts:
andforthefirsttimeinforever · 03/12/2025 06:33

I’m using multiple threads, am I?

Do link me to one.

Really, go and find one.

autumnboys · 03/12/2025 06:43

I had to stop due to a health concern. I did six months on MJ, hoped/expected to have the option of taking it for maintenance. It’s been nearly 9 months since my last jab. I have put in a couple of kg, although that jumped up shortly after I started HRT and I think it’s related. I have to be very careful about what I eat and I’m at the gym 5 times a week. It’s hard work. I would love to have the option to go back on them, the food noise is miserable, but being healthier than I was does help me not to always succumb.

Oblomov25 · 03/12/2025 20:57

Reading with interest.

TheRealGoose · 03/12/2025 21:19

IndigoBluey · 02/12/2025 23:54

Some very insightful responses. To those questioning my curiosity, I can’t really explain anymore than I have done already. I’m genuinely curious as to the long term, sustainable goal. I know how hard weight loss is and that my journey is nowhere near as hard as many of you.

My journeys been brilliant to be honest, I feel so much better on the drugs, as Said bmi 20 now, staying on a maintenance dose, been about 7 months, my days aren’t hard, they would be if I came off, I’d be feeling deprived, watching the scales, but on a maintenance dose, no it’s honestly great.

20bloodypounds · 03/12/2025 21:30

3flyingducksarrive · 30/11/2025 03:31

You imagine wrongly. The science shows differently. It's not about changing mind and body.

Some people will maintain the loss, the majority will not and will need a maintenance dose or to come off and on the drugs lifelong. Diet, Drugs and Dopamine is an excellent book which discusses the science of obesity and just why it is so hard to keep weight off longterm.

It's quite a difficult one about what the science says... All the science about stopping / not stopping / maintaining / regaining that I have seen are people on prescribed medication, following (obviously as part of a controlled trial) a contolled regime.

I've not seen any actual science about the vast number of people who are paying for private prescriptions (the £££ has got to be a different motivation for maintaining the weight loss). There are some excellent support threads on here, either specifically about maintenance or as part of the 'cohort' who started with you. Many of them are really uplifting - people sharing diet, food menus, exercise regimes. It's a self generated support network that was not available to any of the people on the published trials that I have seen. Many anecdotal (and self-reported) posts of being able to maintain successfully.

And reading some of those threads, I defy any scientist to create a valid study. People's choices are so varied. Reducing gradually, coming off cold turkey, spreading out doses over longer periods, staying on a low dose, taking it intermittently (one month on / 2 months off).

I guess ultimately the proof will be in the published statistics about the levels of obestity.

3flyingducksarrive · 04/12/2025 01:01

Diet, Dopamine and Drugs by a former head of the FDA goes into the science and it's fascinating. Really worth a read.

IndigoBluey · 04/12/2025 01:19

@andforthefirsttimeinforever. You asked me to post your other threads, I searched and have tried to post your responses (as requested by you, but surely you know what you posted?) as you can see they have been deleted. You will have received a direct message, which describes your abhorrent conduct. Do better.

What happens when people stop the injections?
OP posts:
andforthefirsttimeinforever · 04/12/2025 07:09

Thags a post, not a thread.

Sorry, do you only want people to reply once? I know my first reply was deleted. I was sarcastic in it is why; what I said was that this board is full of stories of friends who lost weight and then gained it, and the palpable delight from their ‘friends’ is obvious.

You claim this isn’t you, OK then. I still haven’t been posting on multiple threads about this.

OopOop · 04/12/2025 07:33

IndigoBluey · 04/12/2025 01:19

@andforthefirsttimeinforever. You asked me to post your other threads, I searched and have tried to post your responses (as requested by you, but surely you know what you posted?) as you can see they have been deleted. You will have received a direct message, which describes your abhorrent conduct. Do better.

Edited

‘Abhorrent conduct’ is absolute hyperbole. How do you describe things that are actually abhorrent?

andforthefirsttimeinforever · 04/12/2025 09:17

I do think there’s an element of a wind up here. I posted a sarky response; MN deleted it, fair enough. That’s somehow now abhorrent content across multiple threads? 😂

HappyWineDay · 04/12/2025 09:43

@3flyingducksarrive I agree, it’s a fascinating read and really delves into the science around obesity, citing many experts and studies.

IndigoBluey · 04/12/2025 23:31

@OopOop if you are unsure of the meaning of the word, you should pick up a dictionary. No point asking others as to how it is interpreted

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IndigoBluey · 04/12/2025 23:35

@3flyingducksarrivethis looks incredibly insightful, thanks for sharing, I plan to read it this weekend

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IndigoBluey · 05/12/2025 00:11

@TheRealGoose. I’m so happy for you and glad that your journey is going so well. Well done and keep up the positive attitude!

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Wallywobbles · 05/12/2025 04:25

What does reduced inflammation look/feel like? I read and see it a lot on social media but not sure what this is in reality.

OopOop · 05/12/2025 08:13

IndigoBluey · 04/12/2025 23:31

@OopOop if you are unsure of the meaning of the word, you should pick up a dictionary. No point asking others as to how it is interpreted

Edited

I know the meaning of the word, that’s why I made the comment I did.

TheRealGoose · 05/12/2025 09:26

Wallywobbles · 05/12/2025 04:25

What does reduced inflammation look/feel like? I read and see it a lot on social media but not sure what this is in reality.

For me, it was for several years I couldn’t do a sitting kneel, ie where you kneel down and rest your backside on the back of your heels. As my ankles didn’t bend back, and my ankles were also stiff in the mornings and didn’t work properly, within a couple of weeks of starting the drugs, I could do a sitting kneel and also no more morning stiffness in my ankles, I am sure there is more, just that’s what was visible as such to me.

KilliMonjaro · 05/12/2025 12:59

TheRealGoose · 05/12/2025 09:26

For me, it was for several years I couldn’t do a sitting kneel, ie where you kneel down and rest your backside on the back of your heels. As my ankles didn’t bend back, and my ankles were also stiff in the mornings and didn’t work properly, within a couple of weeks of starting the drugs, I could do a sitting kneel and also no more morning stiffness in my ankles, I am sure there is more, just that’s what was visible as such to me.

See this isn’t about weight then is it? How do we deal with inflammation once we come off?

putthehamsterbackinitscage · 05/12/2025 13:06

You have to decide if you want to come off mj and the how to support your health through food and lifestyle. There are various anti inflammation diets etc you could adopt to help.

i am coming round to the idea that I may titrate down as low as possible but stay on mj for the foreseeable so long as money permits.