Meet the Other Phone. Only the apps you allow.

Meet the Other Phone.
Only the apps you allow.

Buy now

Please or to access all these features

Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Is there justification for continuing with Mounjaro no for MH reasons even when a healthy BMI?

175 replies

ThisNeedsToWork · 10/11/2025 10:41

So my BMI is now 24, which I’m obviously overjoyed with. My eating habits are better and I’m exercising more. However, I’ve been here before; many times. One of my biggest issues is the food noise. I find it overwhelming to the extent that it actually causes depression. Over the years, I’ve tried anti depressants, none of which addressed the cause for me which was the constant obsession with food and eating. Taking Mounjaro has stopped that, dead. It’s been life changing for me. I had no idea the beneficial effects on my MH would be so profound. As an aside, my joints are so much better too. I’ve been down to this size a few times before in the last 10yrs with no real difference in my aches. So, my question is really whether it would be reasonable to stay on a low dose for the foreseeable not so much for maintenance but rather for the enormous benefits it’s had on my mental health?

OP posts:
Flipflopskid · 12/11/2025 19:02

Periperi2025 · 12/11/2025 17:20

It's early days, i only dropped the dose 6 weeks ago.
My energy levels have definitely recovered.

Thanks for sharing ! Your strategy sounds like a good one . Less is more and all the best for your hair issues. Being free to eat enough + have energy can only be good!

MeridaBrave · 12/11/2025 20:46

thesugarbumfairy · 12/11/2025 17:01

I have to say I don't ever want to come off it if I don't have to. I don't currently have a provider as I stockpiled before the price increases, and I have plateaued for 6 months (BMI still 26) but if I wasn't on it I know exactly what would happen. Life is SO much easier now.
Not just the getting up and putting on anything and feeling like I look ok because I'm a fricking size 12 - that bit is brilliant - but the reduced pain (I have osteoarthritis and already had a hip replaced at 48 so that pressure being taken off my other dodgy joints has really helped significantly)
I sleep better. I don't get the shakes ever (I suspect I had low blood sugar often before, although I never consulted a gp about it) My skin is better because I'm conscious about drinking more water.
Its just. Better. And I CANNOT go back to how I was. I'm not sure if I'm going to be able to find a provider now that will put me on maintenance once I run out though. We shall see. I'm still technically obese because I'm mixed race.

Why won’t you find a supplier for maintenance? As long as order with a year of last order.

MeridaBrave · 12/11/2025 20:59

LizzyEm · 12/11/2025 10:03

Once you understand your diet has to be that way for life, and its not just for dieting, its easy. I now consider myself allergic to refined carbs, UPF, junk etc the same way I am to wheat. It gives me the same inflammation response so I can't eat those 'foods', end of. There's no choice if I want to be healthy.

You might say oh but there is a choice, you can take injections, but why would I want to inject myself with god knows what just to take away inflammation so I can eat shite? I feel WELL eating clean, I didn't feel well or healthy or have energy to exercise etc on Rybelsus and the injections are worse by all accounts.

I'd rather eat properly and get the same glp response naturally, for free and without risking whatever the long term effects or complications these injections are going to have thanks.

yes I accepted this in 2002, when I lost weight on a low carb whole foods diet. As you say it’s for life.
Not just UPFs, all refined carbs - haven’t eaten pasta or pizza or chips. My friends all think I have disordered eating as I won’t eat pasta or rice or chips or tropical fruit or ice cream etc.

And really I haven’t ever lapsed (I mean yes had occasional ice cream on holiday, but only occasion lapses but despite that I gained a lot of weight in each pregnancy (from whole foods). And when stressed (from whole foods) and in peri menopause (from whole foods.) And that’s as someone who is totally consistent in the gym. It’s true I never got to obesity with whole foods - but did get to a BMI of 27 which is why I am now taking MJ.

I’m curious how long you’ve maintained your goal weight for? my longest is likely around 4 years and that was with constant vigilance.

PolyVagalNerve · 12/11/2025 21:05

MeridaBrave · 12/11/2025 20:59

yes I accepted this in 2002, when I lost weight on a low carb whole foods diet. As you say it’s for life.
Not just UPFs, all refined carbs - haven’t eaten pasta or pizza or chips. My friends all think I have disordered eating as I won’t eat pasta or rice or chips or tropical fruit or ice cream etc.

And really I haven’t ever lapsed (I mean yes had occasional ice cream on holiday, but only occasion lapses but despite that I gained a lot of weight in each pregnancy (from whole foods). And when stressed (from whole foods) and in peri menopause (from whole foods.) And that’s as someone who is totally consistent in the gym. It’s true I never got to obesity with whole foods - but did get to a BMI of 27 which is why I am now taking MJ.

I’m curious how long you’ve maintained your goal weight for? my longest is likely around 4 years and that was with constant vigilance.

Your experience is such a typical story of women’s metabolic changes through the life span -
the person u quote, I don’t want to encourage her to join the conversation again, but she said she has not achieved a goal weight yet, therefore has not experienced weight maintenance post weight loss

MeridaBrave · 12/11/2025 21:07

PolyVagalNerve · 12/11/2025 21:05

Your experience is such a typical story of women’s metabolic changes through the life span -
the person u quote, I don’t want to encourage her to join the conversation again, but she said she has not achieved a goal weight yet, therefore has not experienced weight maintenance post weight loss

If she hasn’t had 5 years+ of maintaining how can she be so sure she won’t gain weight only eating whole foods?

Gettingbysomehow · 13/11/2025 06:52

Ive been on it for a year and lost 5 stone with 6 pounds to go. Im on 7.5.gs any higher and I start getting nauseous. Im going to decrease gradually then stay on 2.5mgs for the foreseeable.
I've completely gone off food and have to make myself eat. I was an emotional eater.

Maaate · 13/11/2025 20:02

Pumpernickelbrakes · 10/11/2025 12:57

GLP-1s should be viewed IMO as metabolism management medications not “weight loss jabs”. Entirely reasonable to stay on them long term to manage the chronic condition of obesity, diabetes, PCOS, and other related conditions and that is, in fact,what they were designed for. Obesity is a symptom of metabolic dysfunction.

This.

GLP1 is a hormone produced by the body, just as insulin, thyroxin, oestrogen, etc. are. It's perfectly reasonable to supplement hormones if you are not producing the right amounts naturally and it is having an effect on your health and wellbeing.

When taking a GLP1 medication we still have to make the choice about what we put in our mouths but now we aren't at a disadvantage because our bodies aren't working in quite the way they should

ThisNeedsToWork · 14/11/2025 15:20

Sorry not to come back sooner, we’ve just been away for a couple of days.

Just wanted to say thank you so much to you all for contributing to what has been a really useful thread for me. I had absolutely no idea that the joints thing was so widespread. I thought it was just a strange beneficial side effect that I was experiencing.
And yes, I’m also someone who ordinarily has ADHD brain. Im not diagnosed but 2 of my 3 kids are so I recognise it well. Usually, when new information arrives it just squishes everything over a bit. My brain never makes room by filing stuff away. Everything is just in there constantly shouting at me. That is, until I started on MJ. I had assumed the ADHD noise, as a pp called it, was quieter because I wasn’t feeling depressed but I’m not sure it’s not just part of the overall calm I’m feeling. My house is tidier and I’ve stopped procrastinating over everything.

The more I think about this, the more I want to stay on MJ for ever! 😅

OP posts:
putthehamsterbackinitscage · 14/11/2025 18:29

I chose Mounjaro over wegovy for precisely the wide range of other benefits people are reporting - inflammation reduction, hormone balance etc. still only in month 1 but I can notice differences already and my friend who has been taking it longer says she has been able to drop other meds including hrt as her symptoms were massively changed.

im not sure I would drop hrt completely but hope to be able to reduce from 4 pumps of destroyed eventually. Money not withstanding I could see me choosing maintenance too.

MeridaBrave · 14/11/2025 21:42

putthehamsterbackinitscage · 14/11/2025 18:29

I chose Mounjaro over wegovy for precisely the wide range of other benefits people are reporting - inflammation reduction, hormone balance etc. still only in month 1 but I can notice differences already and my friend who has been taking it longer says she has been able to drop other meds including hrt as her symptoms were massively changed.

im not sure I would drop hrt completely but hope to be able to reduce from 4 pumps of destroyed eventually. Money not withstanding I could see me choosing maintenance too.

I’ve cut HRT estrogen from 3 pumps to 2. I was taking HRT before MJ but noticed that if I missed a dose I didn’t get night sweats! Which def happened before MJ. Anyway cut back to 2 pumps and all seems good.

Darkchocolatecookies · 15/11/2025 08:20

Interesting thread as I noticed right from first jab I was super sensitive to MJ and yes do have adhd genetics in my family (both my teenagers diagnosed) plus the effect on reduced joint inflammation & reduced brain fog was overnight. I’ve had a lifetime of exercising lots, cooking from scratch, tried every “diet”, run marathons and triathlons but always my entire adult life had an overweight bmi which turned obese with menopause and nothing I did could calm my mind or lose weight. I then lost easily 1lb a week every week on MJ down 3.5stone maintained for a year now but still need 2-2.5mg to do this. I tried stopping but felt awful again within 3-4wks. I’m short and subsequent my “maintenance” calories are only 1300 per day, so I fast daily, I increased my protein and halved my carbs just to stay at bmi24. There’s 100% a link for me in how dopamine is being used or released in the body and this drug. I hope I can stay on a low dose for a long time like my mum who has to take statins to keep her cholesterol low despite a lifetime of exercise & healthy bmi her diet alone wasn’t enough.

Darkchocolatecookies · 15/11/2025 08:25

And yes I too reduced my HRT as there’s a link between oestrogen body uptake and fat reserves this drug for me interrupted this in a positive way. Honestly I’ve never felt healthier in my 50s, lighter, fitter and brain works so much better after many many years of debilitating brain fog through my 40s with peri-menopause thought I’d have to leave my job. Now I have far more days of hyper focus instead of panicking about what ive forgotten I’m taking on extra projects. The impact of MJ has been life changing for me.

FirstdatesFred · 15/11/2025 17:41

I'm not sure how you can know you wouldn't need it for weight maintenance anyway? I will be staying on for maintenance, I don't think it matters your reason why. If you don't need it to control your eating you'd just have to be careful you don't continue losing weight when you want to maintain

wordywitch · 16/11/2025 10:31

My mental health improved pretty much instantly after starting Mounjaro and my chronic inflammatory back pain has also improved drastically. I was taking painkillers twice a day and am now completely off them. I have my life back. It’s been absolutely life changing and I plan to stay on it as long as I possibly can.

Dollybantree · 16/11/2025 10:42

LizzyEm · 10/11/2025 10:44

I think you'd be unreasonable because you can get the same effects though diet. Don't go back to eating processed junk, eat whole foods and keep the carbs complex and low and you shouldn't get food noise. These injections replictate the effect low carb etc has in the body imo.

If you eat shite when you come off you'll just end up fat again and be trapped in an endless cycle.

🙄

Dollybantree · 16/11/2025 10:47

GiveMeWordGames · 10/11/2025 11:52

Isn't it nice that @LizzyEm has bothered to come over to the WLI section and taken the time to give the OP her delightful patronising advice on a topic she demonstrably knows nothing about? Aw, lovely.

I can’t believe people are still trotting out these ignorant, patronising comments - haven’t been on the WLI board for ages and hoped they’d all fucked off by now 😂

Dollybantree · 16/11/2025 11:11

Frenchfrychic · 12/11/2025 08:17

@LizzyEm you still fat and diabetic or did you manage to get the weight off?

Oh how WISH they still had the laughing emoji 😂

Dollybantree · 16/11/2025 11:17

LizzyEm · 12/11/2025 10:03

Once you understand your diet has to be that way for life, and its not just for dieting, its easy. I now consider myself allergic to refined carbs, UPF, junk etc the same way I am to wheat. It gives me the same inflammation response so I can't eat those 'foods', end of. There's no choice if I want to be healthy.

You might say oh but there is a choice, you can take injections, but why would I want to inject myself with god knows what just to take away inflammation so I can eat shite? I feel WELL eating clean, I didn't feel well or healthy or have energy to exercise etc on Rybelsus and the injections are worse by all accounts.

I'd rather eat properly and get the same glp response naturally, for free and without risking whatever the long term effects or complications these injections are going to have thanks.

Who is eating shite? Have you actually taken MJ? It makes it impossible for me to “eat shite” as you put it - as I’m sure it does for most people. Not that I ever had a bad diet anyway.

You are embarrassing yourself now.

Dollybantree · 16/11/2025 11:22

Frenchfrychic · 12/11/2025 13:17

The hair loss is due to the weight loss, not the drug, it is temporary, and comes back very quickly after your weight stabilises. You do end up with tufty bits as the hair grows back, but it grows v fast. It starts growing back within 3 - 6 months of weight stabilising.

basically when you lose a lot of weight the body tries to preserve itself and the hair follicles shut down, meaning you shed a lot more hair. Not everyone gets it. When you stop losing weight they reopen and the hair regrows, my weight has been stable about 6 months now and the tufty bits are a couple of inches long. Think it started coming back a month or two ago.

Sure it’s a ballache, but it is temporary, and happens with any significant weight loss, ie slimming world, fasting, weight loss injections. It’s just more commonly discussed now as so many millions of women are losing signficant amounts of weight. This time next year it will be healthier than when I started, as it is all new fresh hair.

id urge anyone to just keep going with a steady weight loss in the drugs, as being a healthy weight is critical for our health. And the hair regrows fast, re growth seems to be much faster than the rest of my hair. And unless we intend to stay fat, then we are always going to have to go through it.

This is exactly what happened to me, it’s growing back now. I also take collagen powder and biotin, b12 and iron supplements. I’m so glad I didn’t let the hair thing scare me into stopping. And as you say - it’s the weight loss, not the drug that causes this - it’s always happened to me in the past when I quickly lost a lot of weight, whatever the method.

KimTheresPeopleThatAreDying · 16/11/2025 12:25

@HansHolbein I want to say that I think I love you. Your comment about not wanting to waste any more of your life struggling to lose weight when there’s an option that makes it NOT a struggle really hit home.

But being overweight is seen as a moral failing and for some, making it easier to lose weight is viewed as “cheating”. Fatties must suffer for our sins, apparently.

@LizzyEmI’ve tried keto (and a load of other stuff). I don’t sit around stuffing my face with “junk”. I exercise hard, and frequently. I’m still fat. WLIs have changed my life.

MeridaBrave · 16/11/2025 12:39

KimTheresPeopleThatAreDying · 16/11/2025 12:25

@HansHolbein I want to say that I think I love you. Your comment about not wanting to waste any more of your life struggling to lose weight when there’s an option that makes it NOT a struggle really hit home.

But being overweight is seen as a moral failing and for some, making it easier to lose weight is viewed as “cheating”. Fatties must suffer for our sins, apparently.

@LizzyEmI’ve tried keto (and a load of other stuff). I don’t sit around stuffing my face with “junk”. I exercise hard, and frequently. I’m still fat. WLIs have changed my life.

I see it that way as well. Why would I want to dedicate endless brain space with having to stay vigilant to be slim when I can afford the medication? I know from earlier weight loss efforts that the weight creeps back on over time

Goldfsh · 17/11/2025 09:33

Flipflopskid · 12/11/2025 13:03

Very useful and extremely interesting !
5 clicks from what size pen please?
I’ve been off it for 8 weeks now ( 3 stone down ; 1 more to go) after watching my hair fall out . I’m also getting a bit stiffer in places with more aches re-appearing alongside the remergence of sleep apnoea.
It’s so vital we let each other know what’s happening to us!

Other than the above I’ve more or less maintained my MJ lowest with very little effort and actually still don’t hear the food noise. BUT my mantra today is ‘don't start (eating sugary crap) and you won’t need to struggle to stop ‘ and it’s true.

From the 2.5 pen. It shouldn't be doing anything, but it really is making such a difference. It's actually really frustrating!

Periperi2025 · 17/11/2025 09:37

Goldfsh · 17/11/2025 09:33

From the 2.5 pen. It shouldn't be doing anything, but it really is making such a difference. It's actually really frustrating!

I lost 10kg in 7 weeks taking 1.25mg. So as a maintenance dose, whilst 5 clicks is VERY low, I don't see why it wouldn't make a difference to someone extremely sensitive to MJ.
It makes me wonder what dose i may end up maintaining on, hopefully a tiny one, so i can still afford holidays!!

Goldfsh · 17/11/2025 09:39

Periperi2025 · 17/11/2025 09:37

I lost 10kg in 7 weeks taking 1.25mg. So as a maintenance dose, whilst 5 clicks is VERY low, I don't see why it wouldn't make a difference to someone extremely sensitive to MJ.
It makes me wonder what dose i may end up maintaining on, hopefully a tiny one, so i can still afford holidays!!

Edited

I lost two stone and didn't go over 1.25. I think I'm very sensitive to lots of medication. I'm pretty small. Fingers crossed for you!

Periperi2025 · 17/11/2025 09:47

Goldfsh · 17/11/2025 09:39

I lost two stone and didn't go over 1.25. I think I'm very sensitive to lots of medication. I'm pretty small. Fingers crossed for you!

Yep i'm now 3 stone down on 1.875mg. I briefly went up to 2.5mg but the appetite suppression was so strong and the constipation and lack of energy was unpleasant and i started noticing more hair shedding, so i dropped back down. Now i am feeling the best i have for a long long time, and still have a massive sugar aversion/ sensitivity which is amazing (what i really want is a drug that just does that and nothing else).

New posts on this thread. Refresh page