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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Is there justification for continuing with Mounjaro no for MH reasons even when a healthy BMI?

175 replies

ThisNeedsToWork · 10/11/2025 10:41

So my BMI is now 24, which I’m obviously overjoyed with. My eating habits are better and I’m exercising more. However, I’ve been here before; many times. One of my biggest issues is the food noise. I find it overwhelming to the extent that it actually causes depression. Over the years, I’ve tried anti depressants, none of which addressed the cause for me which was the constant obsession with food and eating. Taking Mounjaro has stopped that, dead. It’s been life changing for me. I had no idea the beneficial effects on my MH would be so profound. As an aside, my joints are so much better too. I’ve been down to this size a few times before in the last 10yrs with no real difference in my aches. So, my question is really whether it would be reasonable to stay on a low dose for the foreseeable not so much for maintenance but rather for the enormous benefits it’s had on my mental health?

OP posts:
PolyVagalNerve · 12/11/2025 08:24

BobbieTables · 12/11/2025 08:12

Really this is a question for your doctor. It doesn't matter what a load of randos on the internet think.

Trouble is … doctors are u aware of the wide range of benefits of these drugs -
they know what it is evidence based for / licenced for of course -

but all the secondary benefits, in addition to weight loss - knowledge base is really scant / in infancy - e.g. there are early stages of research into benefits for arthritis for instance, so the doctors today are not far off as baffled as we are as to the wider benefits

bigboots4 · 12/11/2025 08:25

If I could afford to stay on, I would have. I came off in June, and staying on track has been hard as the food noise comes back, it came back slowly, I’ve recognised it, but it’s hard and miserable. If I could go back on, I would.

LizzyEm · 12/11/2025 08:26

Frenchfrychic · 12/11/2025 08:17

@LizzyEm you still fat and diabetic or did you manage to get the weight off?

I'm nearly at goal.

soupyspoon · 12/11/2025 08:27

I would stay on it OP if you feel you need to, why wouldnt you?

The more information that is coming out about this medication and others like it is that its not just acting on issues around eating, there are a whole host of symptoms and traits that it seems to be supporting and perhaps acting as prevetatives for as well

PolyVagalNerve · 12/11/2025 08:27

NikkiPotnick · 12/11/2025 08:23

Is there a reason why you'd want/need to come off it- cost? Because if you can afford it, sounds like a no brainer!

The cost is certainly one factor,
but I’m also wrestling with the idea that WLI clearly have an anti inflammatory effect - great - but would ai be better on a medication actually prescribed for inflammation. ??
doctors say came off WLI and see what happens
but my concern is if the inflammation returns I won’t be able to get back on WLI as I am no longer overweight !!

Frenchfrychic · 12/11/2025 08:29

LizzyEm · 12/11/2025 08:26

I'm nearly at goal.

And you’re doing that still with a glp 1? Rybelus right?

what’s possessing you fo come on here and preach to other fat people in such a superior manner? Considering you yourself were so fat you became diabetic?

PolyVagalNerve · 12/11/2025 08:29

LizzyEm · 12/11/2025 08:26

I'm nearly at goal.

The research says most people who lose weight, go on to gain the weight and more - and that weight loss is rarely maintained in the mid to long term …

good luck

PolyVagalNerve · 12/11/2025 08:31

Frenchfrychic · 12/11/2025 08:29

And you’re doing that still with a glp 1? Rybelus right?

what’s possessing you fo come on here and preach to other fat people in such a superior manner? Considering you yourself were so fat you became diabetic?

I think she is feeling smug and talking out of her naive arse ! Bless 😂

soupyspoon · 12/11/2025 08:32

BobbieTables · 12/11/2025 08:12

Really this is a question for your doctor. It doesn't matter what a load of randos on the internet think.

Your GP wont really be able to give you informed information about this, if they dont prescribe something they're reluctant to give advice on it I have found

LizzyEm · 12/11/2025 08:33

Frenchfrychic · 12/11/2025 08:29

And you’re doing that still with a glp 1? Rybelus right?

what’s possessing you fo come on here and preach to other fat people in such a superior manner? Considering you yourself were so fat you became diabetic?

No, I only took Rybelsus for 2 months.
Being fat didn't make me diabetic, I've had higher blood glucose since I was a child. I wasn't overweight as a kid.

PolyVagalNerve · 12/11/2025 08:41

LizzyEm · 12/11/2025 08:33

No, I only took Rybelsus for 2 months.
Being fat didn't make me diabetic, I've had higher blood glucose since I was a child. I wasn't overweight as a kid.

so you have metabolic problems. From childhood
your weight control is going to be challenging
dont be too smug
those fat cells you have are permanent
they will fight to be maintained
look up metabolic set points
most of us will have be successful in achieving weight loss in the past ….
it is the maintaining this that physiologically our bodies are hard wired to resist ….

LizzyEm · 12/11/2025 08:44

PolyVagalNerve · 12/11/2025 08:41

so you have metabolic problems. From childhood
your weight control is going to be challenging
dont be too smug
those fat cells you have are permanent
they will fight to be maintained
look up metabolic set points
most of us will have be successful in achieving weight loss in the past ….
it is the maintaining this that physiologically our bodies are hard wired to resist ….

But they don't fight to stay fat or give me insatiable hunger etc if I eat whole foods and keep carbs low. That is my point. You can achieve the same effects as the injections through diet.

KeepYaHeadUp · 12/11/2025 08:45

LizzyEm · 10/11/2025 10:44

I think you'd be unreasonable because you can get the same effects though diet. Don't go back to eating processed junk, eat whole foods and keep the carbs complex and low and you shouldn't get food noise. These injections replictate the effect low carb etc has in the body imo.

If you eat shite when you come off you'll just end up fat again and be trapped in an endless cycle.

IMO being the operative part here.

this is utter rubbish

LizzyEm · 12/11/2025 08:48

KeepYaHeadUp · 12/11/2025 08:45

IMO being the operative part here.

this is utter rubbish

No it isn't, it's common sense.

MeridaBrave · 12/11/2025 08:49

LizzyEm · 12/11/2025 08:44

But they don't fight to stay fat or give me insatiable hunger etc if I eat whole foods and keep carbs low. That is my point. You can achieve the same effects as the injections through diet.

Yes and I have previously maintained my weight in the medium term following that approach (low carb whole food, and exercise). However, in the longer term, despite only eating whole foods for many years (since PCOS diagnosis in 2002) my weight does just creep up. Perhaps a period of stress or uncertainty. Or a pregnancy. Or peri menopause. Or even December / Christmas and suddenly I’ve gained a stone!!

For me, it requires constant vigilance and willpower and eventually it (the vigilance / willpower) snaps. Which is why I’ll probably take low dose longer term (although I plan to take gaps).

Frenchfrychic · 12/11/2025 08:50

LizzyEm · 12/11/2025 08:33

No, I only took Rybelsus for 2 months.
Being fat didn't make me diabetic, I've had higher blood glucose since I was a child. I wasn't overweight as a kid.

Well good luck with that , let us know how you get on getting to a healthy weight and staying there..since you got it figured out.

KeepYaHeadUp · 12/11/2025 08:52

LizzyEm · 12/11/2025 08:48

No it isn't, it's common sense.

no, it’s rubbish

Macaroni46 · 12/11/2025 08:55

@LizzyEm ever heard of lipoedema?

MeridaBrave · 12/11/2025 09:02

Frenchfrychic · 12/11/2025 08:50

Well good luck with that , let us know how you get on getting to a healthy weight and staying there..since you got it figured out.

It’s more staying there longer term. I prob thought that way in my 20s when I was diagnosed pcos and discovered low carb high protein eating. I’m in my 50s now.

PearlTeapot · 12/11/2025 09:04

EVERYONE stop feeding the troll please!

She's ruining an otherwise good thread.

3flyingducksarrive · 12/11/2025 09:07

Ciccici · 11/11/2025 21:03

I'm pretty much at GW now, give or take a few pounds, but I'm still ordering MJ.

It's partly to maintain, but significantly, if I'm brutally honest, to deal with my ADHD. It's like being on holiday from my ADHD brain, which is bloody amazing. I'm calm, productive and present.

It helps to be completely off alcohol as well, because I love wine Grin

MJ is bloody incredible. Wegovy, on the other hand, does absolutely nothing, as far as I can tell. Total waste of money.

I had the opposite experience. Ozempic/wegovy has been great for me but the trial month I did of MJ, I gained weight and struggled,

Goldfsh · 12/11/2025 09:12

PolyVagalNerve · 12/11/2025 08:09

I’m at my target weight
happy to now stay at this BMI (25)
but I’m really wrestling with coming off MJ -
the benefit to my joint health is massive - I used to be in pain, stiff and struggle to mobilise - not anymore
I used to have IBS - gone
brain fog - lifted !!

it’s a drug that has been transformative - I am literally scared to come off it

The SCANDAL really is the lack of clinical advice around these issues. People are just continuing to buy this drug because they are getting no help for all these other things that have been debilitating for years.

PolyVagalNerve · 12/11/2025 09:20

PearlTeapot · 12/11/2025 09:04

EVERYONE stop feeding the troll please!

She's ruining an otherwise good thread.

Agree 👍

TheCowJumped · 12/11/2025 09:35

LizzyEm · 12/11/2025 08:44

But they don't fight to stay fat or give me insatiable hunger etc if I eat whole foods and keep carbs low. That is my point. You can achieve the same effects as the injections through diet.

Edited as @PearlTeapot is right and will ignore from now on.

LizzyEm · 12/11/2025 10:03

MeridaBrave · 12/11/2025 09:02

It’s more staying there longer term. I prob thought that way in my 20s when I was diagnosed pcos and discovered low carb high protein eating. I’m in my 50s now.

Once you understand your diet has to be that way for life, and its not just for dieting, its easy. I now consider myself allergic to refined carbs, UPF, junk etc the same way I am to wheat. It gives me the same inflammation response so I can't eat those 'foods', end of. There's no choice if I want to be healthy.

You might say oh but there is a choice, you can take injections, but why would I want to inject myself with god knows what just to take away inflammation so I can eat shite? I feel WELL eating clean, I didn't feel well or healthy or have energy to exercise etc on Rybelsus and the injections are worse by all accounts.

I'd rather eat properly and get the same glp response naturally, for free and without risking whatever the long term effects or complications these injections are going to have thanks.