Devastated at Mounjaro prices increases!

[missy111]

I’ve been on MJ for nearly a year. Gone from BMI of 42.5 to 39. However, the improvements in my Crohn’s disease and inflammatory arthritis have been the main benefit to me! My Crohn’s has never been better, I am no longer panicking about where the nearest toilet is, and can, for the first time in years, eat fresh high fibre foods without it affecting me badly! My joint swelling goes down linked to when I inject, with swelling and pain increasing again prior to the next dose.

i cannot get the drug on the NHS as it’s not licensed for my conditions, and sadly looks like I will have to stop once the manufacturer price increase kicks in on 1 September.

link to more info https://www.theguardian.com/business/2025/aug/14/eli-lilly-uk-price-weight-loss-jab-mounjaro-trump?CMP=Share_iOSApp_Other

sorry, triple post…

The trouble with that is that in a placebo controlled study you might get placebo. You can’t enroll in a trial with the goal of getting free medication for an unlicensed indication unfortunately it has to be for the altruistic reason of wanting this indication to be licensed ultimately to help yourself and others.

I don’t have trouble believing that it may have good effects on other conditions but NHS Drs are unable to prescribe outside of licensed indications especially for the expensive short supply medications like this. The GI consultant won’t be able to authorise this.

The drug company might ultimately choose to get the drug licensed for other indications but they might not. They are a commercial enterprise and if they can make way enough money for the current indication of obesity I would be expect them to prioritise that and getting it expanded eg to maintenance rather than looking for new indications I’m afraid. When it goes off patent for the original indication is when drug companies start to look for other uses.

It’s sad but not a wholly unique situation. My mum had to pay for her cancer drugs and use up all her savings because the drug that might have given her some hope was not licensed for her specific situation although trials were ongoing. She died anyway but I do not of course begrudge it. We would have done anything to help her. I guess if getting the drug is a huge health priority then its about making some very hard decisions to try to afford it privately.

I expect they are working really hard to do that. This is what usually happens when there is one good successful drug the other companies soon put out very similar ‘me too’ drugs and dilute the market advantage. Lily are a Big Pharma company maximising profit for their shareholders of course they are going to try to charge as much for a medication where there is such huge demand whilst they have a monopoly. I can’t see how Trump is to blame really apart from him giving them a convenient excuse to do this. It makes commercial sense to charge as much as the market will bear and Big Pharma care very little for ethics.

I bet the op has the covid jab!
Nothing else to say about that !

It is possible to get healthcare here.

Buy a lot of pens now before September 1st!
I’ve got 4 on order and I’ve ordered a few for my daughter too!
Ive got enough for 27 weeks or even longer 🤣🤣

What part of buying a drug freely if you can afford it is not capitalism??

And when were big pharma ever accused of being ethical??

Is your daughter prescribed? That's so helpful to all the people struggling to find their next dose..

Yes she’s already using it!
There are some suppliers letting you order 3 pens at once before September ATM!

Now that it a genius idea! I’m off to research any studies being planned and if I find any, I shall be emailing him to ask if I can be forward! Thanks

Inflammatory arthritis (mine is enteropathic arthritis as caused by my crohns) is very diff to osteoarthritis and is an autoimmune disease rather than wear and tear.
my fingers stiffen and swell from day 6-1 of my weekly injection cycle

sounds like some maybe some new medication coming in the next few years but that’s not helping us now. Personally I wish they would hurry up with Elcella which are tablets and said to be a more natural approach. (So hopefully less side effects)

Shame on you. You do sound nasty, you clearly have not understood their thread and you need to take a look at the effect you have on others.

Doesn’t sound nasty at all. She’s right!

I'm glad you'll be able to sleep a little more soundly now then. If the price rises nibble the end off the bell curve then yay, fab. he fact it hammers the responsible 90% clearly means little to you. Give that black heart a reflective look eh ?

Companies can charge what they want! That’s just how it is.

It’s called Capitalism. There’s nothing for TS to get involved with.

Take a breath eh, just because you consider a stone over 12 months not much, that has no bearing on what that actually means for the poster's medical and mental health, Please, don't be so arrogant to imagine you can postulate someone else's experience. How about's you just try and be happy and supportive for someone else here.

Oh get over yourself. I'm happy with absolutely everything i've posted so no need to 'reflect' on anything thanks 🙄.

By all means, don't let something like reading comprehension get in the way of your rant though 😂.

My comprehension is just fine thank you. I wish you well.

My psoriatic arthritis didn’t get that memo and isn’t any better after losing nearly 4 stone sadly. It’s actually worse than it was, most likely menopause according to previous consultant.

Mounjaro hasn’t done anything for the inflammation either. Methotrexate has helped a bit so my dose is being increased but we’ll have to see how my blood tests respond to that as Methotrexate has caused some results to start going out of range.

I’d like to start a biologic and for a fleeting moment during last rheumatology appointment it looked like I might but sadly not.

I’m coming off Mounjaro as I have stalled and don’t want to increase Mounjaro dose and Methotrexate at the same time. I lost more on my own than on Mounjaro so hopefully I will be ok but do have some I can use if not. I just feel really sorry for those that Mounjaro has really helped.

@SeaitoverthereMy mother has Psoriatic Arthritis! She was initially started on Methotrexate injections but couldn’t cope with them
so they gave her tablets she takes once per week. Her bloods liver function was affected at the start but because it helped her inflammation she gave up drinking and follows a good diet plan now. So her liver function is returned to normal. Regular bloods help her keep it that way. She like you, felt loosing weight didn’t help so she eats to prevent
inflamation now and swims (although struggles with this in cold winter)
Good luck - I really hope you get some relief soon. It’s such a horrible condition.

Me too

Its a rotten thing to do so suddenly for those whom now rely on it.

Who

as mine only allow one

@sandwichsue thank you, that is good to know and I am glad your Mum is doing ok . I have tolerated the injection fairly well overall so hoping increased dose isn’t too bad. I don’t drink at all and do try to eat healthily. Although out of normal range for a few results I am still within the hospital guidelines so they decided to increase methotrexate and take me off Sulphasalasine.

It’s my kidneys more than my liver but actually just checked my last bloods and settling down. They are checking my vitamin B and folate levels next week to see if they may account for a couple of things that are out of range on the blood count. I’m on 2 weekly bloods so grateful they are keeping a close eye on me. Fingers crossed the increase in methotrexate works. Also hoping I cope ok off Mounjaro, time will tell I guess.