Articles on benefits of WLIs to health/society/economy, microdosing, social consequences

[FatCyclist]

New Scientist has a series on WLIs and the wider implications to society, the NHS, etc. Here are 6 very interesting articles, full of facts & evidence on the widespread benefits of these drugs, useful to deploy in the very many discussions we all seem to have to have with the very many friends/colleagues/family who are critical, judgemental, and ignorant about the WLIs.

I will keep adding interesting articles to this thread. Please do the same. High quality sources, preferably from popular science mags or scientific journals.

<a class="break-all" href="https://archive.ph/2025.03.28-061954/www.newscientist.com/article/mg26535364-400-the-unexpected-impacts-of-a-society-transformed-by-weight-loss-drugs" rel="nofollow" target="_blank">https://archive.ph/2025.03.28-061954/www.newscientist.com/article/mg26535364-400-the-unexpected-impacts-of-a-society-transformed-by-weight-loss-drugs/

<a class="break-all" href="https://archive.ph/2025.05.22-150104/www.newscientist.com/article/mg26535364-100-what-do-glp-1-drugs-really-tell-us-about-the-brains-reward-system" rel="nofollow" target="_blank">https://archive.ph/2025.05.22-150104/www.newscientist.com/article/mg26535364-100-what-do-glp-1-drugs-really-tell-us-about-the-brains-reward-system/

<a class="break-all" href="https://archive.ph/2025.03.30-222528/www.newscientist.com/article/mg26535364-200-microdosing-weight-loss-drugs-is-on-the-rise-but-does-it-work" rel="nofollow" target="_blank">https://archive.ph/2025.03.30-222528/www.newscientist.com/article/mg26535364-200-microdosing-weight-loss-drugs-is-on-the-rise-but-does-it-work/

<a class="break-all" href="https://archive.ph/2025.03.26-211116/www.newscientist.com/article/mg26535364-300-why-exercise-is-more-important-than-ever-when-taking-weight-loss-drugs" rel="nofollow" target="_blank">https://archive.ph/2025.03.26-211116/www.newscientist.com/article/mg26535364-300-why-exercise-is-more-important-than-ever-when-taking-weight-loss-drugs/

<a class="break-all" href="https://archive.ph/2025.03.30-074640/www.newscientist.com/article/mg26535364-500-glp-1-drugs-are-only-the-start-the-powerful-drugs-to-expect-next" rel="nofollow" target="_blank">https://archive.ph/2025.03.30-074640/www.newscientist.com/article/mg26535364-500-glp-1-drugs-are-only-the-start-the-powerful-drugs-to-expect-next/

<a class="break-all" href="https://archive.ph/2024.12.22-132315/www.newscientist.com/article/2456669-why-do-ozempic-and-wegovy-seem-to-treat-everything" rel="nofollow" target="_blank">https://archive.ph/2024.12.22-132315/www.newscientist.com/article/2456669-why-do-ozempic-and-wegovy-seem-to-treat-everything/

Bummer! The formatting of the links went wrong! I tried to remove the paywall but for some reason that hasn’t worked. So, for each article, click on link, then when it opens behind the New Scientist paywall, copy the url and paste it into the link below, which should give you access to the non-paywalled version.
http://archive.today/

Attempting to post the articles one at a time to see if it works better…
<a class="break-all" href="https://archive.ph/2025.03.30-222528/www.newscientist.com/article/mg26535364-200-microdosing-weight-loss-drugs-is-on-the-rise-but-does-it-work" rel="nofollow" target="_blank">https://archive.ph/2025.03.30-222528/www.newscientist.com/article/mg26535364-200-microdosing-weight-loss-drugs-is-on-the-rise-but-does-it-work/

https://www.newscientist.com/article/2474764-ozempic-weight-loss-is-deemed-less-praiseworthy-than-lifestyle-changes/

thanks, some interesting ones there.

This one might be of interest to anyone else who has lipoedema
https://www.researchgate.net/publication/389426537_Metabolic_Therapy_for_Lipedema_Can_Tirzepatide_Overcome_the_Treatment_Gap

Can you just give a list of what the benefits to society are?

"Our findings show that the current social annual cost of obesity in the UK at around £58 billion, equivalent to around 3% of the 2020 UK GDP. "
In theory if you could completly reverse obesity you could save the uk 58 billion pounds. This would take into account things like the
-Cost to NHS of obesity related conditions
-cost to the economy caused by those who can no longer work due to obesity related conditions.
-cost of carers for those who no longer work to take care of those with obesity related conditions

www.frontier-economics.com/uk/en/news-and-insights/articles/article-i9130-the-annual-social-cost-of-obesity-in-the-uk/

A summary would be nice OP. I don’t want to read all that.
Anything about ADHD in those with normal weight taking it? It would be great if they license it for ADHD then I can lose a few pounds while I’m at it, lower my high BP (genetic) and curb my ADHD linked food habits. I’m not overweight but the benefits to my BP and ADHD would be great. Bet they won’t allow it though.

Thanks for the links @FatCyclist I look forward to reading these articles. Great that a science based magazine has had a more in-depth look at the changes these medications may make possible. Beats all the inane tabloid fodder any day.

Great read. Thank you!

Thank you so much for these @FatCyclist - I have been reading everything I can find about these drugs and had read the start of several of these articles before, so access to the full text is really interesting.

for anyone else using the method above - paste each link into the second search box on the active website homepage as the OP has already archived them. I was tired last night, pasting into the top search and thought it wasn’t working!

Thanks so much for sharing these articles @FatCyclist- it's really fascinating to learn more about how these drugs work and reflect on the social and cultural impacts.

I love the idea of using this thread as a library of reputable info.

I do think it's important to counteract some of the more sensationalist narratives being pedalled by the press, so this can be a really valuable resource for us all ♥️

Ooh I'd like to read this - I've been reading the various trial reports.

Thanks @FatCyclist , a fascinating read so far and will be coming back to read the rest :)

I lost weight with the injections and put it back on.

so thanks, I think I am a life long fatty ans probably need life long treatment

Put back on when you stopped WLI? Had you changed your eating habits from before? Low carb seems to help many maintain any loss. Genuinely interested in why you think you regained as it's a major concern i have. Thanks

I regained it because I was bereaved and sad and used wine and moping to help.

I have a lifetime of bad habits and have been unable to build new good ones - good intentions I have plenty of but I banjax myself very easily.

I think the injections will work but I will need to stay on a maintenance dose. If I weigh less I will be motivated to move more and then I sleep better and that makes me feel better. I need to have a support to nudge me along - I think the jags are it and I will manage with a permanent low dose once I have dropped this bloody awful gut.

Sorry to hear that, bad habits can really take over in stressful times, so very understandable.

I've had a very poor relationship with food for 50 years really. I've only been able to maintain better habits once I changed my diet, some people are ok with moderation of certain foods, but I've finally come to understand that I have to abstain to avoid going off the rails.

Best wishes in finding something that works for you.

Theres a recent trial report from the makers of mounjaro that had people on the drugs for 3 years - people on all their trial groups (5/10/15) maintained their loss while on the drug.

In all groups in just a few months people gained an average of 17% back. I think there is something in our bodies that isnt working/is missing once you have been obese that means I will need to stay on MJ forever. I am joping to come down to a lower (cheaper) dose though when I get to goal.

I think too we see from any major weight loss, whatever the route, 95 % of people regain. I remember reading something (pre MJ) about doctors /the public being cross with people who didn't have "will power" or "discipline" and the ability to keep weight off - yet would you really be cross wiht people for something that only had a 5% success rate. If that was a drug we'd be wary and not expect it to work!

Exactly. I have tried but I have failed. If this works then I am willing to pay for it because I want to be healthy and I am not able to monitor my food alone. I might be part Labrador.

https://www.thetimes.com/article/84157f98-5592-4caa-96aa-184f93d3d5f9?shareToken=ebbeaa2540b7de35c5d931b837c080db

It stopped my nicotine addiction overnight, I almost didn't notice it was so profound. I've heard people say the same re alcohol, an even more problematic addiction. Its fascinating.

Super helpful thank you @FatCyclist 🙏🏼

https://www.theatlantic.com/health/archive/2024/12/diet-exercise-ozempic/680909/?utm_campaign=the-atlantic&utm_content=edit-promo&utm_medium=social&utm_source=facebook

Hmmm, attn grabbing headlines again, but not really killed/killing it though is it? Diet, as in changing food habits, still applies & as people are losing weight, especially those with lots to lose, i'm sure many will become more active. The landscape of traditional D&E is definitely changing, but that's no bad thing from where it is at the moment IMO.

In all groups in just a few months people gained an average of 17% back

That doesn't seem so bad if they managed to keep 83% of the weight they lost off!