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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Week 3-4 lost nothing

26 replies

Hysterectomynext · 25/05/2025 07:56

I’ve taken my fourth Mounjaro but from week 3 I haven’t lost any weight at all. This is despite very low calorie intake. And lots of exercise. This is really worrying me because I have a lot of weight to lose and I started well. Obviously I want to make long term changes but I’m worried that with diet and exercise I am not losing. Very slightly gaining.

another thing is that I ordered another 2.5 pen instead of going to the 5. I was a bit nervous but now I wish I’d gone for the 5. Although I’m not sure what else I can do. I’m taking in less energy than I’m using so logically I should be losing weight. Would higher doses make any difference?

Im going to start next week’s one day early and the same the next week. Then I’m going to use the fifth dose in each of the fist two pens to make weeks 7 and 8 into a higher dose before I order the 5.

has anyone else stalled? I feel disheartened. In the first 3 weeks I lost 6kg

OP posts:
Lostuser · 25/05/2025 08:03

Week 5 and I’ve lost nothing at all as far as I can tell

jeanclaude · 25/05/2025 08:05

What’s your TDEE and your calorie intake?

ThingsgetbetterwithalittlebitofRazzmatazz · 25/05/2025 08:10

You've lost 6kg in 3 weeks! That's a huge amount and it's not reasonable to expect to continue at that rate. It's normal to have the odd week where you don't lose, just carry on and you'll probably have a good loss the following week.

Mounraine · 25/05/2025 08:17

I think a STS of one week is too early to be thinking about altering the process. Why not stick with it and see how you go? Some people don’t lose anything on the loading dose.
(Also I’m not sure I’d want to be using the dregs from a pen that’s been opened 8 weeks).

Time4changeagain · 25/05/2025 08:18

I’m just starting week 52 and have had many many weeks of no loss, I have even gained on a fair few of them too. Yes it’s disheartening when the scale doesn’t move but it will. I’m 1lb off a 6 stone loss, which averages at 1.6lb a week.
I have not gone higher than a 7.5mg dose either.

When you say use the last two pens for week 7 & 8. You shouldn’t use the pens after 30 days so I would advise using the 5th dose on week 5 and the 5th dose of second pen on week 10

Hysterectomynext · 25/05/2025 08:39

Time4changeagain · 25/05/2025 08:18

I’m just starting week 52 and have had many many weeks of no loss, I have even gained on a fair few of them too. Yes it’s disheartening when the scale doesn’t move but it will. I’m 1lb off a 6 stone loss, which averages at 1.6lb a week.
I have not gone higher than a 7.5mg dose either.

When you say use the last two pens for week 7 & 8. You shouldn’t use the pens after 30 days so I would advise using the 5th dose on week 5 and the 5th dose of second pen on week 10

Thank you so much. I’ll do this with the extra dose. Makes more sense. I’ll try to work out whether I could do 3.75 for the next month? I’ll need to do the maths on that one. Has anyone done this?

and yes now I read these comments I feel a bit better. Bound to not always lose I suppose. I think with the excitement I’ve got myself expecting a lot

OP posts:
Incognitoburrito88 · 25/05/2025 08:39

ok you need to calm down and stop worrying. You’ve lost 6kg in 3 wks - that’s a great loss and your body is probably a bit surprised and just trying to find its equilibrium. If you are eating in a deficit you will lose weight. I’m a daily weigher and track my weekly average - I have stayed the same for 8 days in a row before dropping 3 lb overnight - our bodies don’t lose weight in a linear fashion.

as for going up a dose I personally wouldn’t base it just on one weigh in. Are you finding it easy to stay in your deficit or are you battling food noise and cravings? If it’s the former I wouldn’t go up a dose just because of one static weight - if it’s the latter then maybe I would. I’m only on week eight and no expert but my weight has jumped around quite a bit but overall I’m losing 2 - 3 lbs a week (average) and I wouldn’t want it to be faster.

Hysterectomynext · 25/05/2025 08:43

jeanclaude · 25/05/2025 08:05

What’s your TDEE and your calorie intake?

TDEE 2000
intake between 800 and 1200 max

swimming 4 times a week and aerobics once.
walking most days 10k steps. Sometimes 20k

OP posts:
Hysterectomynext · 25/05/2025 08:46

Incognitoburrito88 · 25/05/2025 08:39

ok you need to calm down and stop worrying. You’ve lost 6kg in 3 wks - that’s a great loss and your body is probably a bit surprised and just trying to find its equilibrium. If you are eating in a deficit you will lose weight. I’m a daily weigher and track my weekly average - I have stayed the same for 8 days in a row before dropping 3 lb overnight - our bodies don’t lose weight in a linear fashion.

as for going up a dose I personally wouldn’t base it just on one weigh in. Are you finding it easy to stay in your deficit or are you battling food noise and cravings? If it’s the former I wouldn’t go up a dose just because of one static weight - if it’s the latter then maybe I would. I’m only on week eight and no expert but my weight has jumped around quite a bit but overall I’m losing 2 - 3 lbs a week (average) and I wouldn’t want it to be faster.

Thanks very much.

I’m really hungry most of the time which I think is what’s worrying me about the future. Not sure I’ll be able to fight the urge to eat in the future once the excitement of this new opportunity fades.

yes my body is probably shocked, you’re right.

I have had a year of major health issues and my body has been through a lot of trauma in the last 5 months.

OP posts:
Hysterectomynext · 25/05/2025 08:51

Lostuser · 25/05/2025 08:03

Week 5 and I’ve lost nothing at all as far as I can tell

Sorry to hear this. Have you made big change to your diet and exercise?

getting the right nutrition yet eating at a deficit is key. It’s hard.

OP posts:
Incognitoburrito88 · 25/05/2025 08:52

That sounds tough. I think if you’re hungry it probably is the right choice to go up - provided you’re not starving yourself. I love MJ and am grateful for the effect it’s had on me but it’s not as easy as I thought it would be. There’s so much to worry about.

MrsMiagi · 25/05/2025 11:03

Hysterectomynext · 25/05/2025 08:43

TDEE 2000
intake between 800 and 1200 max

swimming 4 times a week and aerobics once.
walking most days 10k steps. Sometimes 20k

You must be starving! I'd eat a bit more and keep going. It will come off

Histoscientist · 25/05/2025 11:03

If your suppression has gone and food noise has come back then go up. Can you contact your provider and ask them to switch it for 5mg and they bill you to pay the difference? Oushk do this and others may too.
13lbs in 3 weeks is huge, I do believe your body is just adjusting, we all get small plateaus of maintaining as weightloss varies so much, ive had 4 weeks of staying the same in 8 months, they usually coincide with my monthly cycle or eating carbs. Your tdee will drop with almost a stone loss but your intake is too low for all that exercise too, I eat around that as my deficit is 1200 but I don't do any exercise and have an office job. Please think about fueling it more or you will end up exhausted and lose muscle and hair. If you are managing to not be ravenous on that low calories, sounds like the dose might be fine for you so just try to eat a little more.

Histoscientist · 25/05/2025 11:14

Also when my 10mg wore off on 2nd pen with 2 doses left and I was ravenous, had food noise and no satiety, my prescriber advised to take it every 5 days which kicked in the suppression again then I went up a dose. Contact your provider for advice if it does wear off.

Hysterectomynext · 25/05/2025 11:47

thank you so much. I think I’ll inject two days early. I’ve already received the second 2.5 and it’s in the fridge.
im going to try to work out how I can do 3.75 with this new pen.
if I measure and use the remainder from pen 1

thanks for all the support and advice.

and yes I do feel very hungry. But if I don’t eat 500 cal less than I use I’m worried it won’t end in weight loss. And when I’ve tracked calories I’m shocked at how quickly they add up. I have to have been eating 4K plus calories a day before this. I have caused my body so much stress. I had a very near miss this year.

i’ll try to think of this as working even if it takes me extra time.

i also know i need to do more meal planning but im still juggling so many issues.

OP posts:
Hysterectomynext · 25/05/2025 11:48

MrsMiagi · 25/05/2025 11:03

You must be starving! I'd eat a bit more and keep going. It will come off

Yes. Absolutely starving!

OP posts:
MrsMiagi · 25/05/2025 13:40

My TDEE is lower than yours (sedentary job) and I lose average 2 pounds per week eating around 1000 calories. Some weeks half a pound other weeks 3 pounds but it averages to 2 per week. You are active so I'd eat more if I were you. No need to be hungry if you don't have to be. You want to still have energy. I envy your step count.I have a 5000 target that I have to make a huge effort to hit and most working days I don't

KnewYearKnewMe · 25/05/2025 13:49

OP

I initially read your post as having lost nothing at all.

but on re-reading - do you mean you’ve lost 6kg over the month?

if so - please do some more reading and research. Weight loss is not often linear - you’ll lose some, stay the same, go up a little, lose some, etc.

plus the old ‘stand on the weight scales and be happy or sad’ approach is so outdated.

your weight - and weight loss - is much more nuanced. fat loss, plus positive muscle gain, may result in a higher number on the scale, but a brilliant effect on your health and shape.

Smart scales are your friend, as can be regular weighing - I do every other day so to break the ‘success or failure’ cycle I’d built up over decades.

here’s a trend graph from my Renpho scales showing up a little, down a little across the weeks, versus the 25kg total loss since October.

Week 3-4 lost nothing
Week 3-4 lost nothing
mumof1or2 · 25/05/2025 13:53

Mounraine · 25/05/2025 08:17

I think a STS of one week is too early to be thinking about altering the process. Why not stick with it and see how you go? Some people don’t lose anything on the loading dose.
(Also I’m not sure I’d want to be using the dregs from a pen that’s been opened 8 weeks).

Edited because I misread the OP!

autumn1610 · 25/05/2025 13:54

please eat more with all the exercise, it’s not good for you and you need to fuel your body still otherwise you will make yourself ill. As disheartening as it is not to have big losses you need to think what is sustainable and being starving isn’t. Your starving because you body needs fuel. Yes you were eating more calories before but probably not the right ones, just up your intake to allow for the exercise

Hysterectomynext · 25/05/2025 13:55

Yes I use smart scales too.
I’m tracking every aspect of my health.

just that last week I lost nothing despite eating less than I used in calories.

but yes I’ve done lots of reading and research. I’d never assume someone had gone into this without any understanding.

I think maybe my post was too nuanced.

i can see why people often keep WLI use to themselves. There’s definitely an air of assumption that the user is ignorant.

OP posts:
doodleschnoodle · 25/05/2025 14:02

You need to look at it on a macro level, not micro. You’ve lost almost a stone in a month. Would you have lost a stone in a month before it or if you weren’t taking it? I’ve lost 5 stone and if you look at my weight loss chart there’s lots of fluctuations where it goes up, then down, but the overall trend line is downwards across the weeks and months.

If you log using an app like Happy Scale or one of the others, you will be able to see your ‘moving’ weight loss, that is a more accurate representation.

Hormones leading to water retention, just needing a big poo, all that stuff matters when you’re relying a snapshot of your weight on a certain day.

KnewYearKnewMe · 25/05/2025 14:03

I don’t keep my WLI use to myself - everyone I meet is bored of me about it by now 😂😂😂

keep doing what you’re doing, keep tracking the data. If you have a stall for a few weeks and your appetite isn’t suppressed as much, that’s a good time to increase.

like another PP said, I went up to 3.75mg before 5mg to try and lessen any side effects and ensure I could keep as low as possible for as long as possible,

im still on 7.5mg now,

good luck OP!

FortyElephants · 25/05/2025 14:11

Hysterectomynext · 25/05/2025 08:43

TDEE 2000
intake between 800 and 1200 max

swimming 4 times a week and aerobics once.
walking most days 10k steps. Sometimes 20k

What (with all due respect) the fuck are you doing? Why are you trying to create a deficit of 800-1200 calories a day? Who told you to do that? And you've lost 6kg in 4 weeks. You are losing weight exactly as expected. Don't fuck about with bringing days forward. If you can afford it and you want to go up to 5mg now you can use the new pen to double dose (take the pen out and inject in a different site) but don't bring days forward or any of that messing around. And for goodness sake eat enough food. You shouldn't be going under 1200 at all, ever. It's simply not enough fuel for your body to function. Do you want to get loose skin, muscle loss, hair loss and risk of gallstones?

FortyElephants · 25/05/2025 14:12

Hysterectomynext · 25/05/2025 08:51

Sorry to hear this. Have you made big change to your diet and exercise?

getting the right nutrition yet eating at a deficit is key. It’s hard.

If you're only eating 800-1200 a day i can't see how you can possibly be eating enough protein. 1g protein per kg of body weight MINIMUM.

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