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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Piling the weight back on when stopping MJ

632 replies

Richtea67 · 15/05/2025 19:10

Hi all....I'm so disappointed. I lost 3 and a half stone, have been off injections for a month and regained nearly 7lbs 😩. I was a slow loser (1-2lb per week) and focused on changing habits and reducing portion size rather than diets/calorie counting (this has led to binging previously). I have kept up with a lot of the habits (smoothie for breakfast, cutting out alcohol and healthy high protein snacks). But portion sizes have definitely gone up as I'm hungrier! And I've been more tempted by the biscuits at work and the kids treats! Any advice?? I'm considering re starting if I put too much weight on, but financially this would be a struggle, which is part of the reason I came off them. My starting weight was 14.5 stones, weight when stopping injections 11 stones and at present nearly half a stone back on!! Help!

OP posts:
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10
SuperTrooper14 · 16/05/2025 19:23

Annwithout · 16/05/2025 19:14

They are happy to carry on supplying me, just not once I get to 75 😏

Did they explain why 75 is the cut off?

Twiglets1 · 16/05/2025 19:50

It seems the eligibility criteria of some pharmacies like this one:

  • Patients aged between 18 and 74 years.
  • Patients with an initial BMI of 30 kg/m2 or greater.
  • Patients in which a supervised diet, behaviour modification and increasing physical activity failed to achieve a realistic reduction in weight.
  • Patients with an initial BMI of 27 kg/m2 or greater with at least one weight-related comorbidity, i

triopharmacy.co.uk/weight-loss/mounjaro/#:~:text=Patients%20aged%20between%2018%20and,a%20realistic%20reduction%20in%20weight.

Annwithout · 16/05/2025 19:51

Twiglets1 · 16/05/2025 19:22

Lie? Sorry … I’ll get my coat…

They've seen my id documents ...

Twiglets1 · 16/05/2025 20:09

Annwithout · 16/05/2025 19:51

They've seen my id documents ...

Tricky one. Maybe other pharmacies have different eligibility criteria?

AmateurNoun · 16/05/2025 20:14

Annwithout · 16/05/2025 19:51

They've seen my id documents ...

It might be worth starting a separate thread on the age thing in case anyone has found someone who will prescribe at that age.

It looks like there's no prohibition on prescribing it 75+ but they haven't studied its use on that age group and so it has 18-74 as "typical use" and a lot of the online pharmacies are following that.

blubbyblub · 16/05/2025 20:21

SilenceInside · 15/05/2025 21:44

That’s the only option? Yet there are people on the maintenance threads who are not taking a maintenance dose, and are maintaining. Or are they just delaying the inevitable?

No not at all. Like with all diets, many people regain but some don’t. The ones who have changed their lifestyle, maintain smaller portions, increase activity and don’t increase consumption of processed foods are able to maintain without medication.

but if none of the changes that took place whilst on the injection are contained after then the weight will go back on

IrisPallida · 16/05/2025 20:49

blubbyblub · 16/05/2025 20:21

No not at all. Like with all diets, many people regain but some don’t. The ones who have changed their lifestyle, maintain smaller portions, increase activity and don’t increase consumption of processed foods are able to maintain without medication.

but if none of the changes that took place whilst on the injection are contained after then the weight will go back on

Can you cite the evidence for this, about the post diet people 'who have changed their lifestyle' etc blah?

Not the supposition, which is just a variation on the 'eat less, move more' twaddle, but the actual evidence?

Inthebleakmidwinter1 · 16/05/2025 21:00

I think it’s very normal for your body to be ant to gain weight after a period of consistent and prolonged calorific deficit. I’m in mounjaro and my plan is to accept I may need to put a half a stone back on and I plan to reassure my body by eating a really good slightly above maintenance diet for a month or two. I hope you find something that works for you

hehehesorry · 16/05/2025 23:57

Slimfornow · 16/05/2025 18:14

People are obsessed with the idea that people who are overweight are that way because of mental/emotional issues. Do they also think whippets are simply more well balanced than famously uptight and unhappy (yes I’m being ironic) labradors? The difference between them is genetic.

You're not selectively bred to have a thick layer of fat to withstand water and knee high grass full of dew for 4-6h, you just eat too much. Europeans hold more fat around their midsection than most Asians as a rule (similar to your dog analogy), but it's not a matter of hanging stomachs and chafing thighs. It's like saying this dog is like this because of genetics, when it just eats too much.

Piling the weight back on when stopping MJ
ResultsMayVary · 17/05/2025 01:08

aylis · 16/05/2025 13:28

I do this also, not eating until noon most days. In fact I used to be like that for most of my life until I decided to lose weight and inexplicably bought into the 'three meals, breakfast most important' narrative despite it feeling completely counterintuitive to me. Unsurprisingly, it had the opposite effect and felt like it opened the floodgates - once I ate in the morning, I ate until I went to bed. I learned that 'breakfast' doesn't have to be first thing in the morning. It's a good example of advice never being suitable for everyone and that we all have our own path.

I've also learned that this type of 'fasting' can be really helpful for peri/menopausal women in particular.

Edited

Yes this used to be my natural way until I caved into the 'eating breakfast is the healthy way idea'. For me it caused weight gain and was the opposite of healthy!

needtoloseit · 17/05/2025 03:16

.

MoodSwingSet · 17/05/2025 06:49

the labrador analogy is interesting. Yes, the overweight dog is overweight because it eats too much. However, labradors are genetically predisposed to eat too much. It's a lot harder to make sure your labrador is not getting too fat, because by their nature, they will inhale everything edible they see. Friend has a lab and whenever they come over, I have to make sure all food is locked away, otherwise he (dog, not friend) will gobble it up in 2 seconds. They can eat til they are sick.
Whereas I've always had setters - they eat as much as they want, leave the rest. I currently have bowls full of dog food on the floor and they don't care. Still slimmer than the lab.

That's what the book Why We Eat Too Much also describes. Some people are genetically predisposed to put on and hold onto more weight, and combined with food availability nowadays, will put on weight.

blubbyblub · 17/05/2025 07:44

hehehesorry · 16/05/2025 23:57

You're not selectively bred to have a thick layer of fat to withstand water and knee high grass full of dew for 4-6h, you just eat too much. Europeans hold more fat around their midsection than most Asians as a rule (similar to your dog analogy), but it's not a matter of hanging stomachs and chafing thighs. It's like saying this dog is like this because of genetics, when it just eats too much.

Yes but why then are Labradors as a breed programmed to just keep eating? Even when they have a sufficient fat layer? It’s not that one dog in your picture, they as a breed are notorious for eating anything and everything in sights. There may be exceptions but labs on the whole need to have their intake externally managed (by us) or they’ll eat to obesity. Other breeds will eat until they have had enough and stop even if there is food in their bowl.
similarly some people need external management or they will eat to obesity. There has been enough research to inject far some people don’t have well functioning ‘satiation’ genes. Their brains don’t register that they have had enough. Other people have over active satiation genes and they feel full and don’t want any more before they’ve eaten enough and struggle to put on weight.

blubbyblub · 17/05/2025 07:49

IrisPallida · 16/05/2025 20:49

Can you cite the evidence for this, about the post diet people 'who have changed their lifestyle' etc blah?

Not the supposition, which is just a variation on the 'eat less, move more' twaddle, but the actual evidence?

It’s hardly some revolutionary statement that requires a cited thesis.

the medications are an external moderator of appetite. People eat way way less than they used to

some people learn a lot through the process. They realise how little food they require compared to what they ate before. They relearn what a portion size for them actually looks like. They adopt new way of eating. Whether they choose to weight out portions or whether they are able to know going forward that a portion to sustain them is actually a third of what they used to eat, they learn through the experience of being on a WLI what food quantities they need to be eating to stay lean?

if a person continues to eat off the WLI as they did on the WLI then they will remain lean. If they revert to what they used to eat then they will regain.

its not the same as move more eat less. It’s understanding that the WLI affects the receptors in your brain that tell you that you are full. If people learn through using them just how little discrete require and continue to adopt this after WLI then they will remain slim.

Slimfornow · 17/05/2025 08:31

MoodSwingSet · 17/05/2025 06:49

the labrador analogy is interesting. Yes, the overweight dog is overweight because it eats too much. However, labradors are genetically predisposed to eat too much. It's a lot harder to make sure your labrador is not getting too fat, because by their nature, they will inhale everything edible they see. Friend has a lab and whenever they come over, I have to make sure all food is locked away, otherwise he (dog, not friend) will gobble it up in 2 seconds. They can eat til they are sick.
Whereas I've always had setters - they eat as much as they want, leave the rest. I currently have bowls full of dog food on the floor and they don't care. Still slimmer than the lab.

That's what the book Why We Eat Too Much also describes. Some people are genetically predisposed to put on and hold onto more weight, and combined with food availability nowadays, will put on weight.

Exactly this. Labradors have specific genetic differences that make them hungrier than many other dogs. This is why they are prone to obesity. Not because they are emotional eaters who need therapy or because they are weak-willed. Some people are prone to be heavier because they have the same genetic predisposition as labs. We don’t think whippets are morally superior to labradors because they are thinner. It’s much harder to be slim when you aren’t as hungry, as the jabs prove.

Twiglets1 · 17/05/2025 08:43

Slimfornow · 17/05/2025 08:31

Exactly this. Labradors have specific genetic differences that make them hungrier than many other dogs. This is why they are prone to obesity. Not because they are emotional eaters who need therapy or because they are weak-willed. Some people are prone to be heavier because they have the same genetic predisposition as labs. We don’t think whippets are morally superior to labradors because they are thinner. It’s much harder to be slim when you aren’t as hungry, as the jabs prove.

You mean it's easier to be slim when you aren't as hungry, as the jabs prove (your last sentence)

Slimfornow · 17/05/2025 08:56

Twiglets1 · 17/05/2025 08:43

You mean it's easier to be slim when you aren't as hungry, as the jabs prove (your last sentence)

Yes - not had coffee yet!

liann34 · 17/05/2025 09:08

Some people absolutely are genetically programmed to be hungrier than others. I've been tangentially involved with some research on this. A few people also lack hunger hormones - this is probably rarer because its not beneficial in the calorie scare environment humans evolved in. But the elephant is the room on that is the success of UPF manufacturers in creating foods that override human satiety signals. I mentioned this on another thread but since I've worked in this area I've gone much more nanny-state on this. I'm probably also more judgemental, not so m uchabout what people eat themselves, but about what they feed their children. I know I'm l lucky that my exposure to these growing up was extremely limited, largely due to their lack in my parents culture (though this is changing, as it is everywhere in the world). "Everything in moderation" is a good principle for actual food. Not for edible foodlike substances. There are now things on the supermarket shelves that no-one should ever eat. Judging isn't useful, its an emotional response, and the rational part of me is increasingly convinced that the food industry needs more and tighter government regulation, because it isn't going to regulate itself. Its getting worse.

ymemanresu · 17/05/2025 09:10

Motheroffive999 · 16/05/2025 08:13

I changed to Orlistat , bought online, no side effects of you keep meals below 15 g of fat .

hi has this kept the weight off?

IrisPallida · 17/05/2025 10:17

blubbyblub · 17/05/2025 07:49

It’s hardly some revolutionary statement that requires a cited thesis.

the medications are an external moderator of appetite. People eat way way less than they used to

some people learn a lot through the process. They realise how little food they require compared to what they ate before. They relearn what a portion size for them actually looks like. They adopt new way of eating. Whether they choose to weight out portions or whether they are able to know going forward that a portion to sustain them is actually a third of what they used to eat, they learn through the experience of being on a WLI what food quantities they need to be eating to stay lean?

if a person continues to eat off the WLI as they did on the WLI then they will remain lean. If they revert to what they used to eat then they will regain.

its not the same as move more eat less. It’s understanding that the WLI affects the receptors in your brain that tell you that you are full. If people learn through using them just how little discrete require and continue to adopt this after WLI then they will remain slim.

Edited

This is just restating 'eat less, move more' AGAIN. The implication being that fat people do not know or apply this hardly revolutionary knee-jerk obvious answer.

The evidence says otherwise.

If you are going to add your spoutings on a forum, why not actually contribute some educated ones?

IrisPallida · 17/05/2025 10:20

hehehesorry · 16/05/2025 23:57

You're not selectively bred to have a thick layer of fat to withstand water and knee high grass full of dew for 4-6h, you just eat too much. Europeans hold more fat around their midsection than most Asians as a rule (similar to your dog analogy), but it's not a matter of hanging stomachs and chafing thighs. It's like saying this dog is like this because of genetics, when it just eats too much.

Wrong. Just uneducated bollocks, frankly.

www.cam.ac.uk/research/news/scientists-identify-genes-that-make-humans-and-labradors-more-likely-to-become-obese

SuperTrooper14 · 17/05/2025 10:32

liann34 · 17/05/2025 09:08

Some people absolutely are genetically programmed to be hungrier than others. I've been tangentially involved with some research on this. A few people also lack hunger hormones - this is probably rarer because its not beneficial in the calorie scare environment humans evolved in. But the elephant is the room on that is the success of UPF manufacturers in creating foods that override human satiety signals. I mentioned this on another thread but since I've worked in this area I've gone much more nanny-state on this. I'm probably also more judgemental, not so m uchabout what people eat themselves, but about what they feed their children. I know I'm l lucky that my exposure to these growing up was extremely limited, largely due to their lack in my parents culture (though this is changing, as it is everywhere in the world). "Everything in moderation" is a good principle for actual food. Not for edible foodlike substances. There are now things on the supermarket shelves that no-one should ever eat. Judging isn't useful, its an emotional response, and the rational part of me is increasingly convinced that the food industry needs more and tighter government regulation, because it isn't going to regulate itself. Its getting worse.

This is really interesting. It does feel that food manufacturers are given free rein to hook us onto UPFs with no regard for health. If you had to rank the top three worst offenders for UPF, what would they be?

CyclingAddict · 17/05/2025 10:33

There can be a genuine feeling of hunger ..stomach rumbling..feeling a lack of energy/headache...knowing that it’s been 6-7 hours since we have last eaten . A human need in order to survive !

Embracing those feelings of hunger..NOT TO PANIC !

Do we eat to live or live to eat?

Arraminta · 17/05/2025 10:39

AmythestBangle · 16/05/2025 16:56

@Arraminta It reportedly works for smoking as well. I almost wish my DH was overweight so he could be prescribed MJ, as he has tried and failed to stop smoking so many times! (I am not serious obviously!).

Yes, I think that in future the weight loss aspect of Mounjaro will just be secondary compared to the myriad other health benefits it provides.

Blomama · 17/05/2025 10:39

Richtea67 · 15/05/2025 19:10

Hi all....I'm so disappointed. I lost 3 and a half stone, have been off injections for a month and regained nearly 7lbs 😩. I was a slow loser (1-2lb per week) and focused on changing habits and reducing portion size rather than diets/calorie counting (this has led to binging previously). I have kept up with a lot of the habits (smoothie for breakfast, cutting out alcohol and healthy high protein snacks). But portion sizes have definitely gone up as I'm hungrier! And I've been more tempted by the biscuits at work and the kids treats! Any advice?? I'm considering re starting if I put too much weight on, but financially this would be a struggle, which is part of the reason I came off them. My starting weight was 14.5 stones, weight when stopping injections 11 stones and at present nearly half a stone back on!! Help!

Could you try a low dose like 2.5, once a week. You can buy a 5mg pen and use half a dose (30 clicks rather than 60). That halves the cost and makes it a bit more affordable.