I'm starting to wonder if mounjaro is making me feel depressed

[mjcausingthis]

I started about 10th September I think, I've just had to go back down to 2.5mg as I couldn't cope with not being able to eat enough on the 5mg.
Anyway, I do suffer from anxiety which I take medication for and usually it comes and goes. But the last few weeks I am so incredibly down in the dumps, I've never been depressed, it's always anxiety with me so this is new and seemingly out of the blue. I'm starting to wonder if it's mounjaro, has anyone else's who's been on it a good couple of months felt this way ?
I have literally fuck all motivation, I barely leave the house these days. Everything feels like a massive effort, I feel really, meh. Just feel shit and not myself at all!

Very interesting. I've been on for about 18 months now and I feel very meh, but I think I hadn't noticed the gradual creep. I passed a big exam last week and I was just like 'oh' I feel like I am pretending to enjoy things and outside my body if that makes sense. Like ooh that Christmas tree looks nice rather than feeling it. I have another 50lb at least to lose so I will keep a watch on it.

I was getting a bit meh with things. I've started using my blue light and after a couple of weeks, am feeling much better. Don't underestimate how much of an effect winter and poor weather can have on your mood.

Yes. I had low vitamin D in the past with depression so that could be a thing too.

I’m so glad I found this thread. I’m on week 9 of mounjaro 5mg and I’m a completely different person. Someone here described it as going from Tigger to Eeyore and I’ve never related to anything so much. I’m usually the life and soul yet the last month or so I’ve not even wanted to leave the house. I can’t even be bothered to talk to friends and family. I don’t feel down I don’t think, just very meh! I don’t believe it’s food related either as I did keto for 6 months a few years ago and averaged on around 800 calories a day and didn’t feel anything like this.

I’ve been feeling like this too and had to miss my next injection, as I felt so low and fearful. Been thinking if micro dosing, possibly starting with 0.5-1mg. Has anyone tried this and does it help alleviate the feeling of being low?

I felt low on it before Christmas but I took two weeks off the and have been back on it for a few weeks now and am feeling ok this time.

This has been me the last three weeks. I've never suffered from anxiety before and it has been crippling. That and irrational thoughts. I've decided to stop taking it - I was on 7.5mg and started to feel anxious towards the end of the 5mg. I ended up in a&e with palpitations from anxiety and this week was prescribed something for depression and anxiety. I didn't take my 3rd dose as usual yesterday and I already feel less anxious.

I echo the fearful feeling too and my head also felt heavy

Hope you feel better soon. I have started on MJ again and took 2 weeks at 1.25mg to try and lessen the anxiety. I’ve had my first week at 2.5mg on Friday.

What I did find is the notion of taking MJ makes me anxious. So I am making sure I take my injection without the kids around and no distractions. For example when I did the two clicks and cleared the syringe some medicine sprayed on my bed and being anxious I changed the bedding incase the kids somehow ingested it. There’s a feeling of guilt that comes with MJ. If I had been prescribed other meds I wouldn’t feel the same but it feels illicit somehow. I feel like I might drop dead from these meds 🤣

Not to say the meds don’t contribute but I’m trying to separate the anxiety of taking the meds vs what the meds actually causes.

Also second time round my suppression is almost non existent so maybe it’s that too.

Interesting read
I'm on 15 mg and I'm very anxious and depressed,which I've always had since a child .
But I am finding I'm making excuses to not go where I usually go and it's any excuse to get back in to bed

Thank you and you have just explained how I have felt as well, the guilt of taking it and then wondering if it will kill me or cause 101 issues. That could be contributing to our anxiety as well. I hope the anxiety doesn't come back for you again as you go up doses. I am 5kg away from goal with 2 (7.5) doses left. My head feels so clear today and not as woolly as it has been the past three weeks. I am tempted to take 2.5mg but I'm not sure how to reduce the dosage.

It’s removed all the colour from my life. I know I’m not depressed but life is boring now for some reason.

I can see that I last posted on this thread in Dec. I still pretty much feel the same.

Down in the dumps most days.

But putting up with it for now as I need l to see the weight continue to come off. still have 4 stone to go.

You can search how many clicks.

My friend felt the same, just meh. One because of something in the drug and two just not being able to enjoy food, socialise with it etc
once she got to goal weight and came off she felt good again. And eats out again and enjoys food but being healthy most of the time.
We use food to make us feel good in so many ways, it’s hard at first to lose that

It feels more than just meh with me .. it's massively ramped up my anxiety..at least I'm assuming it's mj .
I'm only half way through loosing weight I need to loose ,I will be so glad when I can come of it .
I think to come of it now It would be to easy to go back to square one ..I need to get another few stone of to get out of the woods ..very frustrating I seem to be slowing down weight loss wise as well

I haven’t got anywhere near the suppression I had when I took it back in October. So I suspect that might be why I’m feeling well. I wanted less suppression. But not convinced I have any now!

Sorry you feel like that, I wonder why it’s done that

Are you on the same mg as before?

I did 2 weeks at 1.25 because last time I found 2.5 too much, I’ve done one week of 2.5 now.

I think it was me that said I had gone from Tigger to Eeyore. I have been on mj since Aug 24, still just under 5mg.
I feel as though my mood is not as low as it was at its lowest. Its just that I cant find any joy in anything, not even my weight loss.
I still have a hint of Eeyore and definetly no Tigger yet, I think my current mood would be more Pooh, who has run out of honey...

I think it helped when I accepted that the lowness wasnt really me, it is a side effect of MJ. Its not my fault. I am also doing all I can food wise, eating 30 plants a week and spending as much time outside as I can, I find these things really help.

Sending hugs to everyone who is struggling with low mood. It really is a horrid side effect.

My mood has definitely been much flatter, but unsure if it is Mounjaro or other health issues emerging or that I previously blamed on my obesity. The main ones are -

7st loss so far has messed about with my hormones (estrogen is stored in fat, less fat less estrogen) which can cause low mood and I now on HRT. HRT also takes time to find the right balance .

8 years of omeprazole has caused a B12 deficiency which has many symptoms around tiredness, energy, lethargy. Probably had it for years, but just realising now it wasn’t just severe obesity and working on reversing damage with B12 shots.

I'm on 15 mg as well ,and I feel like it's just stopped working,other than adding to my anxiety.
But I'm to scared to come off it incase I'm wrong and the weight fly's back on .
I've got myself in a catch 22 really.
I actually wish I'd never started taking it .
I wish I'd tried harder to loose weight without it

I posted on this thread in December 24 and I’m pleased to say for me it passed and the low periods were short lived.

I’ve never been more tired in my life. I’m fine during the day at work, as I’m conditioned to be that way! But my evenings are a write-off as all I do is sleep. I would say my moods are probably a bit flat but I don’t think I can blame that on Mounjaro. Think a previous poster made an excellent point about us no longer getting a joyful hit from food/the anticipation of food.
My losses are quite slow, despite eating a high protein diet on a calorie deficit, so I’ll have to reflect on whether it’s all worth it, financially and otherwise!
What I would say to anyone embarking on this journey, is that it’s not a miracle cure.