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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro 1.25mg anyone?

30 replies

JazBag · 11/09/2024 21:26

Hi all,

Have recently taken the plunge after trawling through all of the wonderful and insightful information on this site (the community on here is amazing!)

Today marks the start of my third week and third injection (2.5mg starter dose). I have had great suppression and really pleased with my current weight loss.

SW: 93.2kg
CW: 88.1kg

So a loss of 5kg/11lb in two weeks...

HOWEVER it's not all rainbows and butterflies. I have been suffering from diarrhoea. It's infrequent, but enough to make me consider stopping (it's very urgent and I'm afraid I may get caught short on the school run).

I don't get on with loperamide as I find it bungs me up and the when I do go it's almost as bad.

So I'm debating two options:

  1. Splitting the dose and injecting twice a week (not overly convinced this will make a difference as the diarrhoea doesn't directly follow an injection)
  1. Trying a half dose of 1.25 by counting clicks (yes I know technically we aren't supposed to, but I'm comfortable with getting the bonus dose so I'm already breaking alll the rules lol)

Would love to hear if anyone has done either option, particularly 2!

Thanks so much!

OP posts:
Millionaura · 15/10/2025 21:15

I just counted the clicks to 30. Turn it really slowly and you can count the clicks.

VL931522 · 19/10/2025 19:47

FiFi1964 · 15/10/2025 19:18

Please could someone do a video of how to dial 1.25mg into the pen. Im not sure from reading peoples comments, how to do it. Thanks

Just prime your pen as normal and then slowly count 30 clicks as you turn your pen then inject
A full weekly dose is 60 clicks so you just do 30 instead for half the dose

finalpunt · 19/10/2025 20:15

I microdose now at 1.25mg every 10 days.
Started mj in June on 2.5mg. Like you, suppression was fab but had terrible diarrhoea. Stuck with it and it did get bit better. Went upto 5mg after 5 weeks and SE were horrendous so dropped back to 3.25mg. Dropped again to 2.5mg then 1.25mg. I'm still losing few ozs now. Target was 10st and now 9.8.
I wish I had started slower and just trusted it would work. Drinking over 2lts with electrolytes helped.

Junmaro · 16/03/2026 17:27

Millionaura · 15/10/2025 21:15

I just counted the clicks to 30. Turn it really slowly and you can count the clicks.

@Millionaura
would you update as to how you got on? Interested to know. Thanks.

Millionaura · 16/03/2026 18:01

I moved back up to 2.5 and the side effects disappeared. I think maybe I needed a break. I am currently still on 2.5 but am thinking about moving up to 3.75 as I have plateaued recently.

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