I rescued our Staffie Kenny in January after starting a thread on here about getting a puppy. He continues to be a star and has really made our family complete...
You know there's going to be a but, don't you? 
He suffers terribly with separation anxiety, no doubt as a result of his abandonment and probably being taken away from his litter too early. We stuff him a Kong, put the tv on, don't make a fuss on departure or arrival, he is walked very long walks twice daily, but cannot manage to be on his own without getting into a terrible state.
He is panting and out of breath and really stressed upon our return, and usually has wee'd and pooh'd even if he had been just before we left. Up to now he hadn't damaged anything (except when he managed to trap himself in the bathroom and chewed the door and the skirting board really badly)! Although upon our return today he had destroyed our front door mat. He hates being in an enclosed space, so leave him the run of the kitchen, sitting room with daytime bed, hallway, stairs and landing and ds room, where his night-time bed is. This is after we tried confining him to one room and again he really scratched the door badly.
It is really causing a problem, as my dh struggles to find the compassion for the state that drives him to this to override the wee's, poo's and today a chewed doormat! And I think it may be getting worse not better. Any advice would be welcome.