I lock all the doors or tape them up with no entry signs. The kitchen and lounge I leave open and I take the door off DS's bedroom , and if you can, take the lock off the bathroom door so no one can make out in there ....
Remove all breakables, nice rugs, cushions, put covers over sofa etc. Make sure there's a bin in every room.
It sounds quite over the top but experience has taught me 
I then bunker down in my bedroom but come out occasionally to make my presence known.
They will almost definately try to sneak alcochol in, probably disguised as coke or orange with vodka.
It's also good if a few friends stay the night so that they can help with the morning clear up. I find the dc are far more cooperative with this if they have a friend or two around to help.
I have survived quite a few parties now including cake fights ( make sure no food provided is at all sticky or messy) I also had one guest who managed to vomit on every soft furnishing in the house 
good luck !