I can't use primers either so I have worked out it is the silicone & any alcohol that I react too. I have a few open pores between my eyebrow & the next day I get a blind boil there or a few spots with heads across my forehead.
I have had to go back to using pressed mineral powder Clinique or Jane Iredale.
Is there any liquid foundation that doesn't contain silicones? I did try a Bare minerals one but it streaked after a few hours.