I am on the new layout.
In this box which I am typing in right now the nominal width of the box is less than the width of the text it will accomodate...so it starts scrolling...sometimes...and I write a post, think I have a typo, delete it and realise it is not a typo, the first letter of the word is just missing on the left and I can't see it.
Also because you are on a fixed width page it is annoying for those of us that don't have wopping 19 inchers (starts dreaming about YetMoreTech )...as we have to scroll to see the whole page width wise. It is OK when I maximise though (not sure if I have a whole 19" to enjoy or if I have to make do with a 17")