We did keep the radiators on our upper floor. We have a wet system on the ground floor. We do have old floor boards in the oldest part of the house and left the rads in there. And the fireplace that used to house the cooking range in the Victorian era. Mainly to keep the authenticity of the old cottage. In fact technically a hovel when we went to an open air museum! When built it almost certainly would have had earth floors.
Wet underfloor heating upstairs is difficult to lay for obvious reasons. We have electric ufh in bathrooms though and towel rads on the central heating system. All this was installed 10 years ago and I’m not sure if things have changed!
We have the highest quality glass in our orangery kitchen and wall insulation. I love the overall heat of ufh but this house stays warm and windows are new, doors fit and it’s ventilated properly so we never have condensation. It’s a big house so it’s never going to be cheap to run but it’s as good as we can get it.