3 miscarriages, possibly experiencing fourth . Considering IVF with PGTA

[BoldReader]

I'm looking for some advice and experiences from anyone who has been through IVF with PGT-A, particularly following recurrent miscarriage.

I'm 34 and have a three-year-old daughter. Unfortunately, since having her, I've experienced three missed miscarriages, all requiring surgical management (D&Cs). Currently pregnant but first scan was measuring behind so not holding out much hope.

One pregnancy was confirmed to have trisomy 13, while the other two losses had no identified cause.

I've undergone recurrent miscarriage investigations, which have all come back normal, but we still haven't found an explanation for why this keeps happening.

I'm currently experiencing a fourth pregnancy, which has unfortunately had an inconclusive early scan. I'm obviously hoping for the best, but after everything we've been through, I'm also trying to understand what our options might be if this pregnancy doesn't progress.

I've started looking into IVF with PGT-A to see whether testing embryos for chromosome abnormalities could potentially reduce the risk of another miscarriage.

I'm based in Northern Ireland and have been looking at clinics in Belfast, but I'm also considering travelling elsewhere in the UK or even abroad, if the costs and treatment options are better.

I'd really appreciate experiences of:

• IVF with PGT-A following recurrent miscarriage.
• Whether PGT-A made a difference to your experience or outcome.
• Clinics in Belfast or elsewhere in the UK that offer reasonably priced PGT-A.
• Anyone who has travelled to Europe for IVF and genetic testing.
• What the actual total costs were, including medication, embryo biopsy, genetic testing, freezing and frozen embryo transfer.
• Whether anyone found PGT-A worthwhile at 34.
• Whether anyone was advised to have PGT-SR rather than PGT-A following a trisomy 13 pregnancy.

I know IVF and PGT-A aren't guarantees, and I'm not assuming this is necessarily the right route for us. I just feel I need to understand all the options after three losses and would like to feel that we're doing everything reasonable to investigate why this keeps happening.

Thank you so much to anyone who takes the time to reply. ❤️

I sure hope this doesn't land with you the wrong way. I just wanted to give you any possibility of hope.

We had 4 losses. Last loss confirmed trisomy 16 and 21. I did generic testing, they said I had a chromosomal issue that doesn't affect my day to day life but affects my fertility.

Told me I qualified for IVF PGT Testing. My husband and I were onboard in January to do it.

Only issue was we heard you should be as healthy as possible and waiting list could take 1 year (both of us overweight) we changed our eating habits and lost weight.

Whilst waiting for IVF we thought we may as well keep trying as I'm 34, partner is 37.

We got pregnant in May and I'm now 28weeks pregnant - furthest along I've ever been and I believe it'll be a successful pregnancy.

Just encouraging you not to lose hope. Of course go ahead with IVF if thats where you are mentally but there is hope.

Wishing you the very best.

Thank you so much for sharing your story. It definitely doesn't land the wrong way at all — it's actually really lovely to hear a positive story after so much heartbreak.

I'm so sorry for everything you've been through, but how wonderful that you're now 28 weeks and have reached further than ever before. I really hope the rest of your pregnancy goes smoothly and you get to bring your baby home. ❤️

I think I'm just trying to explore every possible option at the moment. After three losses, one confirmed trisomy 13, it's difficult not to feel that we need to do something differently, even though my investigations have all come back normal.

It's reassuring to hear that pregnancy can still happen naturally, even after repeated losses. Thank you for reminding me not to lose hope.

Do you have any tips for what I could do differently? I'm already on cyclogest with plan to start clexane if fetal heartbeat is seen.
Wishing you all the very best for the rest of your pregnancy. ❤️

Hey @BoldReader,

I'm happy to share what worked for me. I actually received the advice from a lady on mumsnet.

When going through my last loss in December she shared that both she and her partner switched to a "whole foods diet."

In January both my partner and I began eating whole foods only. Our carb sources things such as sweet potato / quinoa etc. Meats we'd eat whatever and vegetables and fruit we'd eat whatever. But of course it had to be a whole foods meal not covered in sauces etc.

We went cold turkey no alcohol for the whole period too.

I also for the first time began taking supplements : Folate (rather than folic acid), COQ10, and vitamin D tablets.

Did this from January 2026 until May 2026. May we decided to keep trying naturally as IVF could take a while and I fell pregnant. We also incorporated exercise and both lost weight during the period (but we were overweight)

I took progesterone from the day I found out I was pregnant and 75mg of aspirin.

We never had issues getting pregnant just the baby remaining with us.

I did take clexane in my third loss and unfortunately it was my quickest miscarriage loss I don't know if it was connected as some women it really helps but didn't help me.

Happy to answer any questions at all.