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Still experiencing pregnancy sickness at 22 weeks despite anti-sickness medication

3 replies

Madsmoo · 01/09/2026 21:18

Hi,
22 wks pregnant with my IVF bsby and still experiencing sickness, tried 3 different anti sickness meds but none stop the sickness.
They all reduce the sickness but cause me to start getting nighttime sickness. From 10pm - 2/3am I am unable to sleep as I feel so nauseous at night, then around 2/3am I am sick and then sleep ok - I am exhausted!
Below are the meds I have tried so far:
Xonvea
Ondansetron
Cyclizine

Anyone else, had this?

OP posts:
ALovelyPinkUnicorn · 01/09/2026 21:23

Hi, know how you feel, the hyperemesis thread on here got me through, will have good advice

SKLM · 01/09/2026 21:40

I had this with my first pregnancy. The anti sickness that worked best for me was promethazine, because it is also quite sedating, so it got me through the nights.

I'm sorry you are going through this, it's so horrible isn't it. The doctor might also be able to try a combination of anti sickness medications. Good luck xx

Madsmoo · 02/09/2026 08:24

SKLM · 01/09/2026 21:40

I had this with my first pregnancy. The anti sickness that worked best for me was promethazine, because it is also quite sedating, so it got me through the nights.

I'm sorry you are going through this, it's so horrible isn't it. The doctor might also be able to try a combination of anti sickness medications. Good luck xx

Thank you, going to see my GP again x

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