What medication helped with severe early pregnancy nausea when cyclizine did not?

[NaomiTroll]

Hi,

Looking for advice regarding nausea in pregnancy and medication you can take. I’m currently 7 weeks with baby no.3 (if all goes well). I dealt with severe nausea and some vomiting in my previous two pregnancies and my first was particularly rough - vomiting at least once a day until around 16 weeks. I’m fortunate enough that it’s never developed into HG - which sounds absolutely awful.

But the nausea in this pregnancy is so severe. It’s all day long, 24/7. I haven’t vomited yet but I know it’ll become unavoidable soon. I eat healthily and workout intensely 3/4 times a week but I am now averse to basically any food, can barely climb the stairs without being exhausted and stomach is rolling, and I have two children to look after. It’s at the point where even opening my mouth to talk is nauseating. After forcing food down myself I have to lie down with my eyes shut for several minutes to stop myself chucking it back up again with the nausea.

GP prescribed me cyclizine which has been about as useful as a chocolate teapot. Still just as nauseous (if not worse) and also incredibly drowsy to the point where I don’t feel safe caring for my children - as soon as I sit down my eyelids are drooping.

I suppose I’m asking - what has worked for other people? And do people think I could be prescribed Xonvea even if I haven’t started vomming yet (though I know I will)? I’m living on the outskirts of Cambridge if that’s useful in terms of where meds are available.

Pregnancy is such a gift, that is not lost on me, but omword it can be so miserable and isolating.

Cyclizine worked for me but a friend who had really bad sickness found that Xonvea was the only thing that helped at all. Evidence shows that starting medication before symptoms get really bad is more effective than waiting, so I’d use that to try and get the Xonvea now.
Mine was never as severe, but I got prescribed cyclizine as soon as I got a positive pregnancy test the second time round, even though I didn’t even have any symptoms yet.

Cyclizine did zilch for me so 3 days later I asked for something else and was prescribed Xonvea which worked brilliantly. I had severe nausea but no vomiting.

Promethazine worked much better for me when cyclizine didn’t touch the sides!

I tried cyclizine, Xonvea and prochloperazine. In the end, ondansetron was the absoloute winner. I took it right up to delivery in both pregnancies

Promethazene worked well for me. I was actually prescribed Avomine tablets for travel sickness- could clearly see the box under the prescription labels! Give it a try, was a life saver.

Seems like It’s a personal thing to whether a medication will actually work for you. I was first prescribed Xonvea which has great reviews, but due to the timings it had to be taken didn’t work well for me at all. I needed something that could be taken at any time of day, so I was eventually prescribed Metoclopramide. Which works well but does tend to make my reflux a little worse, so I only take when desperate.

Xonvea all the way. I had cyclizine and prochlorperazine as well at various points and both of them did nothing for me.

Thank you all! Appreciate all the feedback. I’m in Cambridge and apparently you need specialist referral to get Xonvea in this area… :’( I’ve been prescribed promethazine which is making a minor difference, but when I go camping for six days in a row I might splash out and privately buy some Xonvea because it’s the one I’ve consistently heard the best reviews of (still not completely perfect though of course).