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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

High risk Combined Screening Results

2 replies

Lrgreen · 16/06/2025 20:51

So I had my dating scan last week but was measuring ahead at 14+1. For some context, this is an IVF pregnancy and I was advised to take all of my IVF medication until my dating scan which includes two forms of progesterone (Lubion and Cyclogest) and oestrogen (Progynova). I am also 32 years old.

The sonographer initially said the nuchal translucency was measuring 3mm and said that was normal but noted in my maternity notes she put the measurement down as 2.8mn which was reassuring.

I went on to have the blood test as part of the combined screening and results came back today as high risk of baby having Down Syndrome (1 in 41 chance).

Blood results showed low slightly low PAPP-A at 0.67 and HCG levels are elevated at 3.3.

I have experienced a lot of nausea and vomiting which would suggest elevated HCG levels and I wondered whether the IVF medication may have impacted the accuracy of the results.

I am awaiting a date for an amniocentesis for a diagnostic result but was wondering if anyone had experienced similar results from the combined screening and went on to have a healthy baby? And has anyone on IVF medication been told this can affect the combined screening results?

OP posts:
WorriedMamma2 · 17/06/2025 03:48

Sorry to hear that you're having such a worrying time right now. I personally haven't experienced anything similar (but I didn't want to read and run). Having said that, an old friend had her results come back as a high chance but baby wasn't born with Down syndrome. Their baby was conceived naturally so not sure about the ivf medication.

You've done the right thing by booking the amniocentesis if this will give you peace of mind or help you prepare for next steps moving forwards, should you get a postive result.

Good luck! I wish you a happy and healthy remainder of your pregnancy. 🫶🏻

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