All children are different.
Not a truism, just true.
I have 2 DSs and they are very much not the same at all. I also have a DD and she is a different child again.
Of course, en masse girls may be more docile and placid (eg in a classroom situation) but none of us have got 30 children (I hope).
Any individual girl can be as hard to deal with as any boy. When DD was little she was a real terror - tantrums, screaming paddies, refusal to do anything except on her terms - stuff I never experienced with the boys.
Now they are all older DS1 is giving us the worry, but no doubt DS2 will throw up a problem soon
It's the joy of parenting.
So in short, the answer is no, not necessarily.
And yes, boys' toys (Lego, Brio, K'nex) much better IMHO. Also boys' hobbies - football, cricket, Cubs - yes I know girls can do these things but sadly not many do (tho my DD is a very eager Beaver!)
BTW 4 and 2 are their ages OP? Yes, when DS1 was 4 and DD2 and DS2 a baby, we couldn't leave the baby with...DD she was shocking in her behaviour towards him!