My DD2 is two weeks old & is literally inconsolable when awake. She screams & screams until she sounds hoarse. Nothing stops it. Laying down, cuddles, sling, dummy (hates it), every hold position under the sun, pram .. not tried the car as we aren’t allowed out for a drive 😩 she just keeps on screaming. When she finally conks out (usually in an evening) she sleeps for 3 hour blocks. Feeding OK, is formula fed, 2/3oz every 2/3 hours.
My first DD wasn’t an easy baby so I’m well versed in newborns being tricky. I was prepared for it coming. But DD1 was never this bad. Something would settle her eventually, often the pram. But I can’t find anything to settle DD2..!
We’ve used colief for 5 days to no obvious effect and now trying infacol as well but I’m not convinced wind is the issue. She burps & farts like a trooper! It doesn’t seem trapped in any way.. 
She does seem a bit refluxy, she constantly has milk washing back into her mouth, swallows a lot & grimaces. And has at least one projectile vom of a feed each day.. that in itself just seems to startle her, she doesn’t cry about it & immediately wants more milk!
Any thoughts? I’m so hesitant to have to take her out to a GP at such times but equally, it’s awful to hear her crying for 10 hours solid! And our elder daughter gets really upset about it.. which is just relentless given we are trapped indoors all goddamn day.. ðŸ˜