I do most of mine when DD (almost 16 mths) is awake. She has always been very good at entertaining herself, and we have a safe zone where she can play where there isn't anything she could hurt herself on, so I pop her in there when I need to get on with something. It's in the middle of the house so if I'm downstairs I am continually passing her and talking to her or stopping for a few minutes play etc.
She only naps for 30 mins a day, and her bedtime and DH getting in from work tend to run into each other which means once she is in bed I'm usually doing dinner so can't really do it then and by the time that's done I'm knackered!
She likes to 'help' push the vacuum around and she likes to dust so I often let her help me do the dusting.
She is fine to be left whilst I run the vacuum around upstairs, or clean the bathroom, strip beds, whatever. I do tend to do one upstairs job, then go play for a while, then do another job and so on - but I honestly think that's more about me worrying that I'm not engaging enough than her being bothered.
Things like ironing, we have a room divider, so I will be on one side ironing, DD on the other with toys, so we're in the same room chatting away, but I get stuff done and she is safe and not trying to swing off the iron flex.