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Menopause

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Utrogestan hopelessness

142 replies

Moredarkchocolateplease · 02/04/2023 15:23

I have just finished my third round of utrogestan.

I feel absolutely hopeless. Like nothing will ever get better again. I feel numb. I am crying, can barely be civil with my family, am livid about everything and I'm swearing at the dog. I'm utterly exhausted too, the deep sleep makes me so lethargic.

I felt like this in month one and two but then increased my oestrogen for month three and felt amazing for a week and hoped it might over ride the progesterone depression.

This is how I have felt on three different pills and to an extent even in my natural cycle I would have days like this around ovulation. But everyone said body identical is gold standard.

Have you felt like this and if so what option worked best/would you go for?

Vaginal application of the utrogestan
The coil
Another kind of progestin
Stopping HRT despite how amazing I felt for one week out of the 12!

Thanks in advance for any useful feedback!

OP posts:
Moredarkchocolateplease · 23/04/2023 11:41

*utrogestan vaginal pessary for the avoidance of doubt 😁

OP posts:
JinglingSpringbells · 23/04/2023 12:16

Moredarkchocolateplease · 23/04/2023 11:40

@Sausagerolex

I am the OP 🙋

I am using the 200mg vaginal pessaries for 12 days a month, vaginally. Prescribed by GP registrar.

I previously took the 100mg tablets x2 orally.

FWIW there was a recent shortage of ALL Utrogestan and the 200mgs have sometimes been in very short supply. In the past- a few years ago- I accepted 2x100mgs instead of the 200mgs on the script .

They aren't actually listed as 'pessaries'. The packaging lists them as capsules.

vjg13 · 27/04/2023 10:36

I'm taking the 200 mg capsules for 14 days on and then off. I do find I sleep better but have incredibly unpleasant vivid dreams that seem to stay with me all day. I'm 55 but started HRT in January having had a last period in September so the nurse practitioner suggested 6 months before changing to 100mg daily.

Does anyone experience similar dreams and did it improve when you changed to daily?

vjg13 · 27/04/2023 10:37

I meant I'm taking 200mg as 2x100mg just for clarity.Blush

LifeInAHamsterWheel · 27/04/2023 16:39

Are any of you on the mini pill as well as Utrogestan? If so, do you take both vaginally or just the Utrogestan? I currently take both orally and continuously (alongside estrogen patches)

CorsicaDreaming · 29/04/2023 22:25

@HairyKitty - this is the thread I mean x

Diningtableand6chairs · 30/04/2023 10:15

I have a question - I'm oestrogen sensitive (similar to OP) and take utrogestan vaginally for the first half of the month. I still get bad emotional symptoms though. I have a bleed afterwards, even if I sometimes forget and only use about 7-8 tablets.

My question is, as long as someone has a bleed then surely it's having its protective effect against cancer? So if the bleed can be triggered by only 7-8 tablets then it's safe to only use that many?

Thanks for any advice, am desperate.

Abra1t · 30/04/2023 10:22

Do you mean progesterone intolerant?

JinglingSpringbells · 30/04/2023 11:04

Diningtableand6chairs · 30/04/2023 10:15

I have a question - I'm oestrogen sensitive (similar to OP) and take utrogestan vaginally for the first half of the month. I still get bad emotional symptoms though. I have a bleed afterwards, even if I sometimes forget and only use about 7-8 tablets.

My question is, as long as someone has a bleed then surely it's having its protective effect against cancer? So if the bleed can be triggered by only 7-8 tablets then it's safe to only use that many?

Thanks for any advice, am desperate.

Are you actually forgetting @Diningtableand6chairs or are you just not using 12 days because you get symptoms?

Your other option is to use a 3-month cycle where you take utrogestan for 14 days every 3 months. This is called long cycle and is in the NICE guidance. You'd need to discuss with your GP.

Evidently, a bleed is not a sure sign that some cells have not become irregular, although it's not that likely. Presumably you are using 2 capsules a day for each of the 7-8 days?

They say the minimum ought to be 10 days so can you stretch to that?

Diningtableand6chairs · 30/04/2023 11:12

Sorry yes intolerant (I wasn't sure if they meant the same thing, basically feeling extremely depressed and hopeless, almost suicidal though I wouldn't go through with it).

Yes genuinely forgetting, as I use them last thing at night, one per night. I'm a bit worried about the 3 month cycle, I asked my GP - well I've spoken to a few at my surgery and none had ever heard of mood issues with progesterone - and they insisted on 12-14 days every month.

If I did that a 3 month cycle I think I'd pay for scans every 6 months to check everything's ok.

Maybe one a night for 10 days/month is the least I should take.

Thanks so much for the replies.

Diningtableand6chairs · 30/04/2023 11:13

Sorry progesterone intolerant not oestrogen!

JinglingSpringbells · 30/04/2023 12:19

Diningtableand6chairs · 30/04/2023 11:12

Sorry yes intolerant (I wasn't sure if they meant the same thing, basically feeling extremely depressed and hopeless, almost suicidal though I wouldn't go through with it).

Yes genuinely forgetting, as I use them last thing at night, one per night. I'm a bit worried about the 3 month cycle, I asked my GP - well I've spoken to a few at my surgery and none had ever heard of mood issues with progesterone - and they insisted on 12-14 days every month.

If I did that a 3 month cycle I think I'd pay for scans every 6 months to check everything's ok.

Maybe one a night for 10 days/month is the least I should take.

Thanks so much for the replies.

The dose is 2 capsules- 200mgs- each night. Not one.

JinglingSpringbells · 30/04/2023 12:22

If I did that a 3 month cycle I think I'd pay for scans every 6 months to check everything's ok.

That's totally unnecessary. I was on a 3-month cycle for 6 years and have reduced it to every 6 weeks (under a consultant.) I have a scan approx every 18 months.

You also need a consultant to scan you not just someone doing 'baby scans' as many of them aren't doctors. A scan by a consultant who can look for anything unusual costs around £250-£300.

Ringsender2 · 30/04/2023 19:39

Just letting posters here know that in Ireland we are advised we can take utrogestan tablets orally or vaginally. The pharmacist who dispensed them to me told me that.

I've just read the leaflet (after 7 months on HRT 🙄) and seen that it's supposed to be taken at bedtime. This is because some women get tired or dizzy (I do - only just made the connection!)

The leaflet mentions oral dose only (but see above for pharmacist advice).

belle1903 · 20/05/2023 07:30

Hi all just a bit of advice. My period has come a week early and I'm on day 9 of utrogestan. Do I keep taking it for another 3 day or stop and start again in 14 days?

Camdenish · 20/05/2023 08:26

I keep taking the utogestran tablets for my full 12 days whatever bleeding happens during the cycle.

Second month of trying vaginal utogestran. My mood was much better. Not perfect, but better. Bloating only happened on day 11 and 12. Bleeding is happening on day 11 or 12 instead of randomly. The doctor said although she couldn’t recommend taking it vaginally she knows people do.

JinglingSpringbells · 20/05/2023 08:39

The doctor said although she couldn’t recommend taking it vaginally she knows people do

I wonder why she said that?.

It's somewhat ironic as many specialists prefer women to use it that way if they want to.

The UK is the only country where it's not actually licensed to use it that way. In France they've used it that way for decades.

Someone here who posted is in Ireland and (now they are in the EU) says the instructions on her Utrogestan says use either way.

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