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Menopause

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Utrogestan hopelessness

142 replies

Moredarkchocolateplease · 02/04/2023 15:23

I have just finished my third round of utrogestan.

I feel absolutely hopeless. Like nothing will ever get better again. I feel numb. I am crying, can barely be civil with my family, am livid about everything and I'm swearing at the dog. I'm utterly exhausted too, the deep sleep makes me so lethargic.

I felt like this in month one and two but then increased my oestrogen for month three and felt amazing for a week and hoped it might over ride the progesterone depression.

This is how I have felt on three different pills and to an extent even in my natural cycle I would have days like this around ovulation. But everyone said body identical is gold standard.

Have you felt like this and if so what option worked best/would you go for?

Vaginal application of the utrogestan
The coil
Another kind of progestin
Stopping HRT despite how amazing I felt for one week out of the 12!

Thanks in advance for any useful feedback!

OP posts:
purplefacemask · 17/04/2023 19:04

People who are sensitive to Utrogestan tend to do better with Dydrogesterone (Femoston)

Moredarkchocolateplease · 17/04/2023 19:10

@purplefacemask ive said to the GP that I will give this a month but unless I feel better I'll move onto something else. So femostan might be next!

OP posts:
Moredarkchocolateplease · 17/04/2023 19:14

@JinglingSpringbells thank you. Agreed it will be a waste of plastic if they come with that many applicators!

OP posts:
Comeshinewithme · 17/04/2023 21:26

Newgolddream70 · 16/04/2023 21:42

I am so happy to have found this thread! I was prescribed the 75g oestrogen patch and couldn't believe how amazing I felt .... then Utrogestan went and spoiled everything. I stopped everything and went back to using the Evorel Sequi 50 patches but the oestrogen isn't strong enough.

Eventually, after weeks of trying to get an appointment with my GP, she advised to go back on the 75g patch but take one tablet of Utrogestan for 25 days of the cycle. After I'd put the phone down I read that you only took one tablet a day for longer if you were in menopause (which I'm not). Will I still get a bleed? Obviously I need to as still have a uterus.

I'm a bit confused as to what to do now. I'm starting the 75g patches again tomorrow and I can't wait for the relief which I know will come quickly.

I am not in menopause and take daily Utrogestan. Don't get the horrible lows I was getting when only take it for 2 weeks of the month. Probably been taking it daily for over a year now, and no problems.

cleowasmycat · 17/04/2023 21:28

Menopause is actually just one day. It's exactly one year after your last period. Anything up to ten years prior is peri-menopause and after if post menopause.

Newgolddream70 · 17/04/2023 22:20

Thank you @Comeshinewithme Smile

Annasgirl · 17/04/2023 22:28

Hi OP, I could not tolerate Utrogestan - vaginallt or orally, and I could not tolerate the Mirena. I am now on Duphostan - not bio- identical- and 2 months in I am still ok - no side effects.

so perhaps suggest that if you can’t tolerate the new version of Utrogestan

BOOTS52PollyPrissyPants · 18/04/2023 16:59

Same here with take utrogesteron it leaves me soo tired and am going to make appt with dr to see can I take it vaginally also after reading all the answers on here as they are very helpful.

SamR36 · 18/04/2023 20:40

My Gp said no to taking it vaginally, but i did anyhow 🤷🏻‍♀️ i couldnt tolerate the fatigue taking it orally.
After being on here and so many women stating that their menopause consultants gave them the ok to take it vaginally i went with it. Im not saying its great, but far better than before. No headaches which is a bonus

JinglingSpringbells · 19/04/2023 07:57

BOOTS52PollyPrissyPants · 18/04/2023 16:59

Same here with take utrogesteron it leaves me soo tired and am going to make appt with dr to see can I take it vaginally also after reading all the answers on here as they are very helpful.

@BOOTS52PollyPrissyPants If your GP says no, what then? It's not licensed in the UK for vaginal use but is in other countries in Europe. You're possibly better just getting on with it.

BOOTS52PollyPrissyPants · 19/04/2023 19:36

Am in Ireland so hopefully will get the go ahead and it will stop the extreme tiredness that never experienced in my life when on the progesterone cycle every month with that tablet.

Mumskisail · 19/04/2023 19:44

Read all of these posts. I'm the absolute opposite!

I feel like the world is ending if I don't take Utrogestan. So even though I'm early peri menopause, I'm allowed to take it every night, just one, in my Daisy. Anyone else like me?

WolfFoxHare · 22/04/2023 08:38

Mumskisail · 19/04/2023 19:44

Read all of these posts. I'm the absolute opposite!

I feel like the world is ending if I don't take Utrogestan. So even though I'm early peri menopause, I'm allowed to take it every night, just one, in my Daisy. Anyone else like me?

In your… what now? 😆🌼

@BOOTS52PollyPrissyPants I agree with Jingling - just try it vaginally, it made all the difference to me. My GP pulls her face a bit but my consultant recommended it.

CorsicaDreaming · 22/04/2023 14:05

Surely you'd like one in your daisy?! @WolfFoxHare 🤣🌼

IfNot · 22/04/2023 14:18

Wondering if my awful depression/ anxiety is due to utrogestan now too....the timing coincides as it's been the last 2 years or so.
Also, if menopause is 1 day, 1 year after your last period, what about if you have another period, say, 15 months after your last period. You revert to being not- menopausal? So confusing!

WolfFoxHare · 22/04/2023 14:29

CorsicaDreaming · 22/04/2023 14:05

Surely you'd like one in your daisy?! @WolfFoxHare 🤣🌼

Sounds more comfortable than up my chuff, at least 😂

CorsicaDreaming · 22/04/2023 17:07

Yes, much more ladylike @WolfFoxHare
😄🌼

CorsicaDreaming · 22/04/2023 17:16

@IfNot - it is definitely worth trying vaginally, I found a Canesten pessary applicator helps to insert them high enough and without them pinging off all over the place.
Utrogestan was diabolical for me taken by mouth - really affected me emotionally within 24 hours - but seems fine vaginally.

I talked to my GP about it this week - she's a bit reserved about it, it's off licence, but gave it a go ahead on the proviso I carefully watch out for any additional break through bleeding in the cycle, and if so make a further appointment as she said this can mean the lining is getting too thick and it's not working effectively to make it shed.

I've actually found that it seems to be more effective vaginally for me at causing a bleed within two days of the end of taking the Utrogestan- whereas it wasn't so controlled for me taken orally. With the added bonus I don't turn into Jekyll and Hyde for 12 days a month...

WolfFoxHare · 22/04/2023 17:18

@Mumskisail sorry for chucking about the 🌼 - it’s just a new one on me. I think there must be lots of women who take just one a night, one way or another, but I can’t say I’ve heard of anyone who struggled when they didn’t take it, tbh. How long have you been taking it? I’ve been on Utrogestan for about 2 years, taking it vaginally on a 2 month cycle maybe 18 months, and while I tolerate it fairly well now, I think I could cheerfully never take another capsule in my life!

WolfFoxHare · 22/04/2023 17:23

@CorsicaDreaming 😂

Actually now you mention it, I’ve also noticed that taking it vaginally results in a more ‘controlled’ bleed (as well as a shorter and significantly less painful one) - it usually starts within 2 days and is more consistently heavy on the first couple of days, then lighter until it finishes. When I was taking orally, it might take a week before I got a bleed then I’d have heavy and light days without any discernible pattern until it ended.

IfNot · 22/04/2023 19:29

Wait...you put an actual pill up your fanny? Not a different substance ( utrogestan gel?)
My brain is mush, sorry if I'm not getting it!

BOOTS52PollyPrissyPants · 22/04/2023 19:44

IfNot yes it goes up your 'fanny' oh hate that word haha. How long does it take to dissolve up there, does it ever pop out, would love to hear from others about inserting it, do you just shove it up with your finger and will that do the job. Great hearing from other women as get more help on here than at any doctors who look at us as if we are mad.

BOOTS52PollyPrissyPants · 22/04/2023 19:46

Wolffoxhare thank you for all your helpful advice. Sounds so much better re.period etc and hopefully will take away the low feeling and extreme tiredness.

Moredarkchocolateplease · 22/04/2023 21:01

@WolfFoxHare im the OP and started taking it vaginally last night.

I was given a utrogestan pessary, but I could have used the usual utrogestan tablets vaginally instead. (GP registrar prescribed it, totally unbothered, totally on top of everything absolutely unfazed by prescribing it).

I used the applicator it came with, it's a 200mg pessary and it went all the way up.

What I noticed is that my pants were damp this morning, however I had a hideous night sweat around 4/5am so I'm not sure if it's the sweat from that or the utrogestan.

Then mid morning I noticed a lot of white discharge when I went for a wee.

I'm never taking it orally again though so if this doesn't work i will move onto something else.

OP posts:
Sausagerolex · 22/04/2023 21:06

I am VERY progesterone sensitive and hated the utrogestan section for about four months including it vaginally then miraculously it just got better and now I don’t really even notice. It was such a huge relief.

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