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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Disappointed with day 5 IVF update and worried about next cycle

27 replies

Magix86 · 29/06/2026 17:09

We've just had our day 5 update for our second egg collection and can't help but feel disappointed. Wondering if anyone has any advice or can share their stories to give me some hope! I'd just like to understand a bit more really. We're doing a back to back cycle to bank embryos and I'm worried about getting the same or worse results on our next cycle in a few weeks time. I want to do everything I can to get a better outcome next time or I'm afraid we might need to add a third egg collection 😒

We've used donor sperm due to MFI. I'm 39. Have been taking proceive max supplements and omega 3. No alcohol. No caffeine.
Both rounds have been short protocol, first round was ovaleap 150 and an ovitrelle trigger (NHS). Second round was 175 gonal-f and buserelin trigger (private). Same clinic. We're not doing PGT-A

On day 2/3 of both our rounds we had top quality embryos of all that fertilised and I've read the drop off after day 3 is usually due to the sperm rather than egg quality?
I've also wondered whether the buserelin trigger may have caused a lower fertilisation rate and possibly poorer outcome? I'm really not sure.

Round 1 in 2024:
16 eggs. 13 mature. 11 fertilised with ICSI.
2 x 5 day blastocysts - 1 x 4AA, fresh transfer and baby boy. 1 x 3AB frozen.

Second round just now:
16 eggs. 12 mature. 8 fertilised with ICSI. 1 x day 5 blastocyst 4BB

I'd be really grateful for any insight, anecdotes, advice for how we can prepare for the next round and anything we can maybe consider changing with our protocol or what we can aim to discuss with our clinic.

OP posts:
TheFanciestPants · 22/07/2026 10:03

@Magix86 fingers crossed for your third round!
Absolutely, we transferred our frostie and had a fresh transfer before starting down the PGT-A testing route. Will you transfer your original frostie or a fresh one from the next round? It's so hard to know, but I think you just have to do what feels right to you.
I am currently at the clinic waiting for instructions. Likely to trigger today, but we will see xxx

Magix86 · 22/07/2026 11:08

@TheFanciestPants we're hoping for a fresh transfer this time if all goes to plan! The consultant said if I have 20 follicles over 10mm then I'll have to have the buserelin trigger again and possibly freeze all. So I'm just praying we get 1 or 2 less follicles than last time lol 😆

Ahhh good luck! How are the follicles growing this time?

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