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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

How many cycles of letrozole before moving on?

3 replies

Muddysocks1 · 20/11/2025 21:00

Did anyone try letrozole before moving onto ivf, if so how long for?

We’re with an nhs clinic and done a few cycles to get good enough progesterone, and they’ve said to try a good 6 months, but this feels like forever if it’s not working? I know it might just take a few goes even if no issue now, but I can’t help but worry what if it’s not the only issue, considering we’ve been TTC 20 cycles now

OP posts:
Muddysocks1 · 27/11/2025 19:53

Just bumping in case anyone has been in this situation ☺️

OP posts:
Tigerlillyrose · 28/11/2025 07:05

I’m at a private clinic but on my 6th and final cycle of letrozole, the clinic told me at the start they would only do 6 months as slightly increased risk of cancer if longer. I’ve had no BFPs but the months have gone very quickly in some ways. I booked my first IVF appointment when I got to month 4 so I can start as soon as possible after this cycle inevitably ends. Feel a little more in control being private I guess as I have had thoughts along the way of bringing it forward but sticking to original plan. Good luck!

2mumlife · 01/12/2025 09:24

Private clinic. We did letrozole and gonal f, but in a medicated IUI cycles (so more control). We did 4 rounds before moving on to IVF (our choice, but clinic agreed). Success rates for medicated IUI with donor sperm drop off after 4-6 cycles

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