REPORT: If a healthy embryo is transferred alongside one of poorer quality then chance of pregnancy is reduced by 27%

[user1470147116]

I am due to have a FET next week and planning on transferring 2 embryos/

I have:

2 embryos at 5 day blastocyst
3BB
4CB

2 embryos at 6 day blastocyst
4CB
5BB

I have read a report that shows if a healthy embryo is transferred alongside one of poorer quality then chance of pregnancy is reduced by 27%.

“IVF pregnancy less successful with two embryos”

www.theguardian.com/science/2017/jan/05/ivf-pregnancy-less-successful-with-two-embryos-study-finds

Out of my embryos above: Which ones are ‘healthy’ and of ‘poorer quality’?

Or are they all about the same?

I wonder of the study means that there has to be quite a large difference in quality for success rate to be reduced by 27%?

Thoughts?

I have heard similar, although plenty of people have a singleton from a double transfer. If you are concerned, why don't you transfer one at a time?

Anything with a C is a poor quality blast. With regards to BB blasts, didn't they recommend transferring one? I would imagine that a clinic would suggest the 5BB on its own.

I had 3 cycles of ICSI and in the last 2 cycles my best embryos were 3BC quality and both developed into pregnancy so don't write them off as too poor quality to transfer.

My instinct would be to do one at a time but I would be guided by the embryologist.

Go by the advice from your clinic :) At the end of they day it's in their interests to get your pregnant for their statistics and getting more customers so they will follow whatever the best scientific evidence to do that.

Also your embryos are all the same quality pretty much so what this paper is talking about (one high quality and one low quality) doesn't sound like it applies for you? It also says if they're all low quality (dk what constitutes low quality) then there is a higher chance of success from two embryos being transferred.

The paper also said that if you have high quality, you are no more likely to get pregnant with two embryos being transferred than you are with one. We recently had two top quality embryos FET. Both implanted. One stopped growing after a few weeks and the other kept going. So for us, if we'd only had the duff one (that was the same high rating as the other), we'd not be pregnant now. Point of my anecdote is we are all individuals and I'd make the decision based on advice from your clinic, not one review paper from one IVF clinic 😊

What age are you?

At blastocyst stage, my personal preference would be to put one back.

These are old numbers, but at the Lists, if you got to the stage of having a blast to put back, your chance of pregnancy rose to 70 per cent. They were very much supporters of single embryo transfer.

Lister, not lists!