Starting first injections of Buserelin, anyone else?

[Wispin]

Did my first needle tonight was so nervous was about to inject myself when I dropped the needle, had to get it ready again, then I just paused when I had to inject myself hovering the needle over my stomach, I couldn't mentally do it, it was like being in a dream where you cant run any faster, I held my breath and did it, I didnt feel a thing, not even when I pushed the liquid in. Will keep posting how it all goes, would love to hear from other people..

Thanks hyland - I would love to be pleasantly surprised!!

If we can't get my lining thick enough to have a fresh transfer, and have to freeze-all, we have a decent plan for next steps for a FET.

First step would be a sort of halfway house between natural and medicated FET. Dr said he'd start me on progynova straight after my period arrives in 2 weeks, and we'd see if we could get the lining to thicken up in time to sync up with ovulation - if so, we'd transfer 3/5 days after ov (hopefully 5 if we get to blast!)

If we can't get the lining sufficiently thick by the time I ovulate, then we won't transfer, but will then start down regging me a week after ov, for a full medicated FET. He thinks the oestrogen receptors in my endometrium will become more and more receptive after cumulative exposure to oestrogen - we just need to 'tune in the antennae', so to speak.

How are you getting on? Xx

I'm in the crazy stage where all i think about is testing.

The what If I'm not side of IVF ..

The bit we all ignore thinking this time it will be different.

Last time i was excited and this time I'm scared.

You triggered today right?
Wish you luck for Monday, what time are you going?

Hoping you dont need FET.

One obstacle at a time :)

Totally understandable hyland, you are doing amazingly!

I find guided meditation / relaxation Mp3s really helpful for trying to destress. The Zita West one on iTunes is all about the 2ww - if you've not already got it, might be helpful (or at least worth a try?)

Think of Rosie the Riveter - we can do it!!!

Yep I triggered last night ('release the hounds!!' as a friend said ) - EC scheduled for 9am Monday morning

Come on eggs, come on lining!!!!

Have some awesome superman socks with little capes on that DH got me to wear into theatre. Last time I wore a pair that said 'let's carpe the fuck out of this diem'!!!

I have listened to about 5 fertility subliminal relaxation 20-30 min youtube, this week.

magic MAGIC superman socks x

Holy moly. Back from egg collection.

17 eggs retrieved!

All 6 frozen eggs from the last cycle survived the thaw.

So that's 23 eggs in the love lab!

They have to do ICSI on the frozen eggs (because they have harder shells) but will do standard IVF on the fresh, as DH's sample was 'excellent'.

Consultant said he wished he knew what was going on with my AMH as he is completely stumped how someone with perimenopausal AMH and FSH has responded like this. But he is very very pleased, as am I!

Lining is 'so so', so I'm desperately hoping the oestrogen tablets help to thicken it up so we can have a fresh transfer. Dr will scan me later this week and we will see where we're at. If there is any doubt we will freeze all, and transfer in a FET, as he doesn't want to risk transferring a decent embryo into a suboptimal endometrium.

But for now, the focus is on trying to get some embryos. Our eggs and sperm are getting jiggy in the love lab so keeping everything crossed for a decent fertilisation rate when we get the call tomorrow!!

23 Now that is something to celebrate. 🎉

Hope your numbers for mature, fertilised eggs that turn into perfect little embryos x

Exciting stuff

You're one step close than before, look forward to your update tomorrow.

Wishing/urging your lining on x

So day 5 blastocyst will be a Saturday transfer is that right?

We have 16 embryos!!!!!

Of the 6 frozen eggs, 4 fertilised.

Of the 17 eggs retrieved yesterday, ALL were mature.

3 didn't fertilise and 2 fertilised abnormally, so we got 12 embryos from that lot.

Holy fucking shit. 16 embryos!!!!!

Not bad for someone who the NHS would have written off and many clinics would have said own eggs were a lost cause and to go straight to donor egg...!!

It does seem like they're very quick to tell women you need donor eggs.

Doesn't make me very trusting of the system.

16 embies yay, very pleased for you

It's pretty black and white for sure. The funding criteria has an ovarian reserve cut off like the BMI cut off. Except you can lose weight but can't make any more eggs.

Although as FSH levels and AFC do fluctuate month to month I don't know how it works if you can go back another month and say 'look I pass the test now'!!!

It's academic for me as we've had two private cycles now so wouldn't be eligible for NHS even though I would meet the reserve criteria now (haven't been TTC for 2 years though - and prob wouldn't meet the reserves criteria by that point anyway)

And lots of private clinics don't want to bugger their stats. And in fairness, many don't want to give false hope, so some will say OK we think your chances are slim but if you really want to try with your own eggs we'll do one cycle. In women with severe DOR this can help them make the decision to move to DE. It's so, so hard and there's no black and white in this business!

How are you doing? When is OTD?

Thinking of you!

Test Friday.... very nervous.

Think we both have our hopes up again.

Oh and I'm convinced i am die to my almost exploding boobs that are very balloon like.

Torturous as i know that swelling sore boobs can be just a sign that I'm due in previously.

Fingers and toes crossed for you Hyland! You deserve it. : )

Not Pregnant.

So sad for you Hyland. Been there and know how it feels. : (
Take care of yourself.

Thanks Amara

...very touched they u have popped back.

Have kept you in my mind even though i was hiding and licking my wounds for the past few months- not at brave as you!
Just let yourself be sad and then work on enjoying life again, being off hormones helps!

Oh Hyland, I have no words. I am so, so, very sorry, my heart is aching for you right now. We are all thinking of you and your DH and hope you can be kind to yourself. Much love and hugs xxx

Hyland, I'm so sorry for you.. I was waiting to see how you got on.. I had a miss carriage just before Christmas at 3 and a half weeks... So I'm starting again on Feb 2nd...xxxxxx thinking of you xx

Wispin Oh no that's not good. Wispin, so sorry for your your loss. :(

Wish you all the best of luck for February x

thankyou Amara and Banana for your comments.

Banana how is your lining?

Amara do you have a next step or still having a breather?

Breather here. I'm thinking of starting a fet cycle in march. Giving myself a rest, getting up to date at work, drinking wine and generally working on appreciating my life as it is and concentrating on not giving a f*ck! I know you must be on the floor hyland but believe me that in a week or two once your hormones settle, you will feel better. Chin up. This whole situation is unbelievably shit (sometimes i can't believe this is what I am going through) but the other things in our lives continue.

I actually dont feel as bad as did after the failed cycle.

It's a little worring to know the next cycle would be us moving into a 3rd cycle/attempt.

Really didnt think it would be this hard.

I knew the embryos were only grade C so i think i knew that it may only be a slim chance.

Dont knowwhat we'll do next
Lap op
a scratch
check NK cells
or straight into fresh cycle

... or even a different clinic!

Partner assumed that coz i didnt bleed this time that it had worked.

I'm sure i had told him that the drugs prevent a proper period.

I guess it's just coz i has bleeding after a week last time!

Oh Wispin I am so very sorry - just heartbreaking

Hyland I hope you're hanging in there - we're all thinking of you

Amara so lovely of you to pop back - living life sounds like the very best idea I can imagine

ET today went really well. My lining thickened up beautifully from 5.5mm at EC on Mon to 8.5mm yesterday. I have a 4AA blast on board, and four good quality frosties on ice.

Dr said OTD was 12 days post 5 day transfer. Better get DH to hide the pg tests so I don't cave and test early!!

So you'll be testing on the 3rd?

Well Done on your frosties and not forgetting your AA blast inside you.

Try not to symptom spot....
Drugs will make your boobs sore anyway. The pessaries will prevent a period bleed so this wont mean you are either. Just remember the only way you'll know is to test on the right day and not any earlier and no symptom will help give it away.

I will be watching out for how you're emotionally feeling and of course your result.

Wish you the Very Best of Luck x

How are you doing Hyland? Thinking of you

OTD is Thu 4th which is a bloody eternity away. 12dp5dt seems a ridiculously long time - but I guess by that point the result is either a definite BFN and hopefully avoids a chemical BFP. Obv the 2ww is already going at glacial pace, need to focus on the fact we never thought we'd even get this far and try and enjoy the PUPO bubble

Really appreciate all your advice Hyland, it really does mean so much

Dr has me on the oestrogen tablets 3 x daily as well as the progesterone in the hope it maintains my lining. Nothing I can do now, either it'll stick or it won't.

Xxxx

The anticipation it to much lol

You'll find it's nice to look forward to something.

Have you taken any time off?