Starting first injections of Buserelin, anyone else?

[Wispin]

Did my first needle tonight was so nervous was about to inject myself when I dropped the needle, had to get it ready again, then I just paused when I had to inject myself hovering the needle over my stomach, I couldn't mentally do it, it was like being in a dream where you cant run any faster, I held my breath and did it, I didnt feel a thing, not even when I pushed the liquid in. Will keep posting how it all goes, would love to hear from other people..

Thanks Amara123, I hope it all goes well for you..

Just had 4 eggs collected this
morning, they are going to let them self fertilise..no isci will know more over the next few days. Husband passed his kidney stone while I was in the op..so that was all good xxx

Amara I hope your 5 fertilise nicely for you both x

Wispin: I hope you 5 divide perfectly to form the perfect grade AA blastocyst for you.

I started bleeding late Monday night.
Just a little on the tissue when i wipe and a bit more than a little by yesterday lunch time. No pains yet but i know they'll come. Since yesterday lunch time i just keep crying, deep down i know its not worked.

This has all cost so much and I feel like Ive failed to provide my partner with a child. It's like knowing you are the biggestest failure to him. All long he was worried about paying for IVF when it has no guarantees. So why on earth would he want to do it again!

We were both so excited and joking about baby names. Now i just feel empty and we both just sit in silence.

wispin (4)

Oh Hyland, I hope you are ok. I would say you don't know if it's really over yet so give it a bit of a chance.

And if it hasn't worked this time it is not your fault! I am beginning to think the whole conception thing is a bloody miracleand involves so many factors, some of which are understood and many which are not. I guess this whole ivf process is such a gamble anyway and none of us knows how it will play out. We just have to trust we will end up with the family we want.

Lots of hugs love.

A

Hyland, I hope everything goes OK for you.let us know how things go, have you phoned the nurses to explain whats happening..they might be able to give advise..? Xx

I called my ivf clinic Tuesday lunchtime and spoke to my nurse.

She told me to take a test, because if it was positive i made need extra progesterone in the form of injections to support the pregnancy.

Unfortunately it was negative, they told me to test still on the 16th day which is tomorrow.

I actually tested again this morning and still negative.

I'll have to buy another test if I'm to test tomorrow.

Still no period pains and the blood is still when i wipe only.

If i was pregnant i thought it would have showed today to be honest.

Amara: did they ket you know how many have fertilised yet?

Wispin: have they given you an update on your 4?

I'm confuse as to whether the progesterone would prevent my period showing up. I have read that it may only show once you fully stop the medication and at the moment I have been advised to continue taking it until tomorrow i guess.

Hi Hyland, out of the 4 eggs collected 3 have self fertilised over night, they are phoning me tomorrow to confirm the quality of the eggs and if any can go back in tomorrow or Monday, let us know how you are tomorrow xxx

Wispin: I hope they keep progressing for you.

I assume tou're hoping for a 5 day transfer!

Hi Hyland and Wispin

5 fertilised and today (day 3) the clinic told me that 4 are growing well and we are aiming for blasto transfer at the weekend! Was so nervous this morning, this is such a roller coaster.

I also seemed to have retained the infamous ivf bloat and none of my jeans will fit! I also have a very bump like side view which makes me worry about meeting people who might think i am pregnant...have had a lot of pregnancy jokes in work recently and it is a bit upsetting.

Hyland I read your other thread and am so sorry you are going through this. Give your partner some space maybe and he will come back when he is ready. People grieve in different ways. Find your support in real life and here and see what happens.

Today is the day i was suppose to test so i did again, like that told me and still negative. Called the clinic and they told me to continue taking the progesterone for another 48 hours and test again Monday just to doubley make sure.

They did say that it was to be expected that i havent had a proper full bleed due to taking the progeterone.

So the torture continues.

My partner is devastated and im a mess, made worse by the fact that he thinks clinics just see us as a number and will continue to make money whilst we're forgotten about.

He's reluctant to go through the process again and again, if at all!
Whilst it eats up what savings we have left. Leaving us with no child or money.

Feeling pretty hopeless.

3 eggs have divided to 5 cell over night, we are now hoping that they will survive to Monday for the transfer back. Hyland I'm still hoping it happens for you..Amara123, let us know how you feel after the transfer over the weekend..

OH my goodness, my period would gave been due yesterday, I had a small bleed and I thought my period was coming..ive Had light spotting since egg collection on Wednesday, there was a little squishy clumps of red blood.. I phoned the on call nurse, she said it would just be from the op, not to worry , I was convinced it was coming but this morning its gone back to light spotting and no pains.....she said it definitely wont come till you stop taking the supositreys...phewwwwww. hoping all 3 eggs make it to Monday.....

Hi Wispin, jusst wanted to wosh you luck for tomorrow x

Hi Amara, did u have tour transfer today? how did it go

Hi ladies

Had my day 5 transfer yesterday- one little embryo back and 1 frozen. Nothing to worry about Wispin as regards transfer, like a slightly longer than usual smear. Not lovely but not bad really.

Actually knackered all the time at the mo. Am off work for a bit more time and glad as I feel totally exhausted. I think the treatment has taken a lot out of me. How are you girls feeling?

Just had my transfer one little embryo back in.. other two wont know till tomorrow as they are not at the same stage..weather they can freeze them or not. Was quite painless nearly cried when I saw it on the monitor screen..so emotional..xxxxxxxxxx

I agree that little white dot was definitely emotional and warching the embryos grow and expand on the video clip.

Pleased you have finally had your transfer, fingers crossed for you both.

How are you doin Hyland?

Inbetween feeling upset and dissappointed to just wanting to get on the ivf road again, to getting angry that clinics dont give u and update after a failed cycle.

For example if i try and book in for another private consultation to move forward, i have to go out of my way to arrange a time/day slot.

Surely i should be entitled to a summary of the procedures and their overall opinions of how it all went, whether by letter or appointment. But if i dont book anything i never get this closure to this cycle.

They told me I would have to wait 10 weeks for an appointment i have to pay for, this should really be apart if the icsi package in my opinion.

Lots of unanswered questions like the doctor reducing the amount of gonal f i took, die to borderline OHSS, did this effect my follicules growing and would this be why i had 11 eggs collected despite having 20 follicules!

Why didn't the two embryos implant, do they think i would benefit from assisted hatching, are my eggs to thick due to age.? Was my lining an issue, did i need more progesterone to support a potential pregnancy,

Do I need extra drugs like intralipids, or a different cocktail of drugs all together.

Do i need to have the test for Nk (natural killer) cells?

Would they recommend doing everything again exactly same way.

Were they surprised that only 7 out of the 11 mature eggs collected were fertilised? Surely they would all fertilise as tgey were all individually injected with a sperm!

Despite the outcome do they think everything well?

This meeting could provide them with us going ahead with another cycle, rather than them assuming we're all desperate women and we'll come back anyway.

Hi Hyland

It must be hard to have these questions and i think that you should make that appointment to speak to them, even if they do take a while. The clinic I am with include this in the price but I am not in the UK.

I think that you had a decent yield of eggs though. I had heaps of follicles like you (18 i think) and only 8 were mature. I had icsi too and 5 of those 8 fertilised normally. So icsi is not a 100% guarantee that all eggs will fertlise, my embryologist explained that those eggs just didn't progress. I guess there is still so much unknown about the process. I suppose too all they can go by is whether the eggs and sperm "look" normal but who knows what is going on at that cellular level.

In the end of the day despite being a statsy person i think none of that matters, it's a matter of luck and the right embryos. (Given that the clinic gives you a fair quality cycle)

Hi ladies, may I join you?

I’ve just started my second IVF cycle, first time on long protocol - started buserelin last week, baseline scan and provisionally starting stims on 1st Dec

My first cycle was short protocol, as I was predicted to be a very poor responder due to exceptionally low AMH and very high FSH. My consultant was astonished when we got 7 eggs, of which 6 were mature - apparently my ovaries had a ‘productive weekend’ between the last scan on the Friday and EC on Monday morning! Unfortunately my lining had a lazy weekend, as it had regressed in the same time, so we had to freeze-all. Due to my DH being poorly on the day, we had issues with a fresh sample so had to freeze the eggs unfertilised.

Saw the consultant last week to discuss next steps, and we decided to do another stims cycle to try and get more to work with - the plan is to thaw the eggs & batch them with whatever we get this time, and fingers crossed we may be able to go to blast. We’re trying long protocol this time as the hope is that with more control over everything, he’ll be able to manage my lining better (esp now we know it’s temperamental).

My last egg collection was only 5th October so wasn’t expecting to be allowed to go again until after Xmas, but thrilled we’re able to crack on.

Not sure what to expect from long protocol - mainly nervous about being over suppressed and not responding to stims. Haven’t had any side effects so far, but probably jinxed myself by saying that!

Just caught up with the thread, big hugs Hyland, hope you can be kind to yourself

Congrats on being PUPO Amara and Wispin

Hi bananafish!

Sorry to hear you had such a tricky go round last time. I bet this time will go better, long protocol can give very good control of the cycle. It will be good to get going before Christmas!

I had all the symptoms in downreg, i was a headachy sweaty betty but you do get through it! I also had extreme bloat at the end of stims but it does all settle and time does pass- you will be fine!

I'll be testing at the end of the week, even though I am tempted to test earlier I'm not going to. I am too scared to get another negative test. I've never had the whiff of a positive one before so I feel like I couldn't hack another negative esp if it was too early and I'd have to do it again!

Fingers crossed for all of us and I hope you are doing ok Hyland. It's a tough experience alright but we are tough ladies!

Thanks Amara - I’m very nervous about not responding to stims after down regging, but when I asked my consultant about this, he said whilst he was concerned about this last time (and hence recommended short protocol), given my response last time & increased follicle count, he felt it was much less of a risk this time. Obv the only way to know is to try and see what happens! Thankfully, as we have the eggs from last time in the bank, even if I respond very poorly this time, we shouldn’t have to cancel the cycle entirely, and will hopefully have something to transfer from the last lot. In which case it’s hopefully a less risky way to find out if long protocol really doesn’t work for me.

Thanks so much for the reassurance about long protocol giving good control - that's really good to hear

Soooo with you on the bloating. I blew up massively after just 4 days of stims - but think it was v much a reaction to the sledgehammer dose I was on at the start - once my dose was dropped I was much less uncomfortable. Though as you say, it goes away really quickly. 36h after collection I had abs back - the transformation was totally bonkers.

Keeping everything crossed for OTD - think your plan not to test earlier sounds v sensible.

Hope you’re doing OK on the 2ww - hang in there! xx