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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Assisted conception after recurrent miscarriage part 5

999 replies

Mel3062 · 14/09/2013 19:37

Hope this is right ladies ...

OP posts:
lemonsherbet · 20/11/2013 20:41

good luck with the LIT.

Mel3062 · 21/11/2013 05:49

Thanks lemon can't say I'm looking forward to it, how are you? X

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lemonsherbet · 23/11/2013 13:27

I am good Mel thanks for asking. Just got a sore throat atm so feeling sorry for myself. Hope the LIT went OK.

lemonsherbet · 27/11/2013 20:36

Didn't mean to kill the thread! Hope everyone is OK

Mel3062 · 28/11/2013 07:15

I know it's gone quiet :( lit was ok thanks just very hot, itchy sore and swollen at mo but that's the side effects and hope til be worth it!

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Arianrhod · 28/11/2013 10:56

lol You didn't kill the thread lemon. I haven't said anything 'cos I haven't got anything going on at the moment, just waiting for DD to get better before I can think of figuring out how to get the money for another cycle.

mel That's interesting, I didn't have any of that when I had LIT done. Does Mr G do it the same way as Serum, I wonder - one injection in 4 sites, being top of both arms and both buttocks? I think you can take an anti-inflammatory like ibuprofen to help if it's too swollen/sore.

Mel3062 · 28/11/2013 17:56

Ooh no I had about 15 injections in each forearm not in buttocks!

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Arianrhod · 29/11/2013 11:37

Oh crikey, no wonder you're hurting!!! Think I'll stick to Serum's way of doing it :)

suemays · 02/12/2013 10:12

pebbles have been trying to pm you, not sure if you have got it??

Mel3062 · 02/12/2013 18:22

Interestingly because I'm on thyroxine from recurrent miscarriage consultant at epu it entitles me to free prescription card!!

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Arianrhod · 03/12/2013 08:31

Absolutely correct mel - I also have this, because I'm hypothyroid. Interestingly though I've since found that I'm in stage 3 of adrenal fatigue, and one of the thing adrenal problems can do is cause you to go hypothyroid. Apparently once the adrenals are fixed it's possible for the thyroid to go back to normal. So if I ever manage to figure out how to fix my adrenal issues, I'll be interested to see if it does help my thyroid as well.

It's all a bit of a minefield, this health business ..

/waves to everyone, hope you're all ok, everyone's very quiet?

Mel3062 · 04/12/2013 09:37

Wow something for nothing! Is it just free prescriptions? Or eye tests, dental etc? I'm only on it as part of tablet trial I'm not sure what my thyroid results were x

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Mel3062 · 04/12/2013 09:38

Niece is pregnant and a friend is, it's so hard seeing scan pics on Facebook :(

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Arianrhod · 06/12/2013 14:58

It's just prescriptions mel. And you should ask for your thyroid results, if you can, so you can keep track as you have repeat tests.

swlondonnanny · 13/12/2013 09:55

Interesting Ari how did they find out / check for the adrenal fatigue? That what my acupuncturist claims as well - that if adrenals are not working properly it makes thyroid worse. Was taking some suplements for adrenals and was told to take much less medication for my thyroid... So that would support that theory I would say...
Also wanted to ask anyone who had a hysteroscopy done - how long afterwards did you keep spotting? And how long did you wait with DTD . Had mine done yesterday - just when my EWCM started!!! Don't want to miss this month but it doesn't feel right to DTD while spotting either...

Arianrhod · 13/12/2013 13:52

'They' didn't, swlondon ... in my many readings on thyroid issues, I saw recommended that you get adrenals tested as they are closely interlinked. So I got in touch with one of the labs recommended on the TUK website (you get a discount) and ordered an adrenal testing kit - if you're interested I'll dig you out the contact details.

Hysteroscopy - I was told to wait to DTD until I'd completely stopped bleeding, as while you're still bleeding your cervix is still open and you could end up with an infection. Ditto to baths and swimming, no-go until you completely stop bleeding. For me I think I spotted for a couple of weeks after both hystos.

swlondonnanny · 14/12/2013 13:40

Thank you Ari, if you could find those details for adrenal testing kit I would really appreciate it. Had quite a few test done 6 or 7 years ago - usually quite a low lever of cortisol ( but within normal range) - would be good to see how it is now. Do you remember what the kit tested for?
Looks like I stopped spotting last night so pleased with it as it looks like I am ovulating today. So all good.
If I can ask how long did you have problems with your thyroid? I was diagnosed when I was 8 so 30 years now...

Arianrhod · 16/12/2013 08:17

swlondon The 24-hour saliva test is through Geneva Diagnostics, called the Adrenal Stress Profile test - details at www.gdx.net/product/10198 . There is also an Adrenal Stress Plus profile which tests for other things too, but I didn't get this as I found the standard test covers everything I needed. Email to [email protected] which goes to a very helpful chap called Paul Eaton (also at [email protected]), You get a discount for mentioning Thyroid Patient Advocacy UK, but you have to email to order the kit rather than going through the online site. I just emailed and said...

"I am advised by Thyroid Patient Advocacy UK, of which I am a member, that I can order a discounted 24 hour adrenal stress profile (discounted cost of £63.75) through you. They advise me to order direct through this email address, and not through the web site.

Can you tell me please how to pay for this? My practitioner is, of course, ‘Thyroid Patient Advocacy UK'."

... and then gave my address for the kit to be sent to. They send you the kit first, then when you send it back for processing you send the payment with it.

Turnaround is very quick, I think I got the result report sent back within a couple of days.

HTH!

Arianrhod · 16/12/2013 08:34

Whoops .. it's "Genova", not "Geneva". Brain's asleep!

Pebbles73 · 16/12/2013 20:43

Thought I would just pop on and say hi, lost the thread for ages and ended up googling it! How is everybody doing?

Not much berm happening with me on treatment front, having a scratch done at beggining of Jan and then straight into starting frozen embryo cycle.

Mel3062 · 19/12/2013 05:12

Good luck pebbles. I'm having second lot of lit therapy to morrow x hope 2014 is a good year for us all x

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duggs1976 · 19/12/2013 08:30

Hello ladies hope everyone is doing as well as us lot on here can do with all this that we carry around. Update from my side. Had the ivf cycle at Hammersmith. Actually quite impressed with them surprisingly. Anyway used same stim protocol as last time 18 mths ago. Responded well got 16 eggs (19 last time). Used ICSI as was planning on doing Chromosonal testing. 11 fertalised. By day 3 10 were doing well all between 6 and 9 cells. One was just a 6. So they decided for a day 5 or 6 transfer depending on genetic testing possibility which is dependent on how many blastyocycts there are on day 5 ( must be more than 3). Day 5 only 3 slowly developing embryos left, just a stage behind blastyocyct. Told to come in for transfer. Went in and only 1 had progressed since the morning check. They put it back with one of the others that hadn't moved and the third was left as wasn't good enough to freeze.

SO.... All in all not great. I don't hold out much hope tbh, but embryologist did comment on good egg harvest and development until day 3 doesn't usually indicate an egg issue, after day 3 the sperm DNA kicks in and here is where they fell off the cliff. She also noted abnormally high number with a hole in their head (sperms) so recommended DH get re checked for DNA fragmentation. He had this done and infection fixed but last test was in January.

Nothing to do with immunes at this stage and seemingly egg qua
It's either. So now DH has booked to see an andrologist week after next.

At least we have some info gained from this cycle.

I am not wondering whether to book ARGC app in which won't come until mid feb prob starting in April or whether to go straight to serum in Athens as I've been reading how much they focus on sperm issues and you can do a DNA fragmentation test of the sperm sample there and then and make informed decisions that way?

Really not sure. Guess we need to wait to see if a) I get pg and then wait for a mc. b) what comes up from the andrologist test.

But still any thoughts as I don't seem to have an issue with me stimulating and the immunes are covered with intrallipids, hydroxy and high dose pred ( I don't need humira or ivig as had those tests).

Sorry for long ramble. Wish people would look at men more consistently throughout all this. Juggling issue after issue. Deep sigh.

Just eaten chocolate father Christmas thatbive bough bunch of for friends kids. 2 are down already since Monday Sad

brownstag · 19/12/2013 09:05

Interesting Duggs and good luck with this cycle. It does seem as if it's more likely to be a sperm problem, but with IVF, aren't they choosing the best ones? Or can they not guarantee they are normal by just looking? I take it your OH wouldn't consider donor sperm in the worst-case scenario?
If the issue is sperm, it would explain why all these many different treatments you've had don't seem to make any difference.

Arianrhod · 19/12/2013 09:42

duggs Interesting to hear what's been happening, and of course I hope that you're lucky with this cycle and don't need to think about going anywhere else.

I'm completely with you on wishing more clinics put equal emphasis on the male factor. So many of us could be having miscarriages due to the male side of things and not know about it, especially if we have issues of our own. It seems to me that when something is found from the female side of things, everyone seems to assume that's it, that's the only problem, when in fact it may well be a male problem too. As brown says, perhaps this may be why that no matter how many treatments you've had, it just hasn't worked so far anyway?

Re Serum - yes, they will test then and there, and if the sperm isn't up to the task they always have frozen donor sperm that they can then use if it's agreed upon. I know of some ladies who had EC, OH's sperm was tested and wasn't great so they used sometimes just DS and sometimes half-and-half to fertilise. I like the fact that they can do it in-house. In fact I think Penny tested OH's sperm for free when we were there, as we'd had it tested (and found to be all ok) a few months previously but she wanted to know the latest state so when we said we didn't really want to pay to get it done again, I believe she told the lab to test it anyway so that she would know it was ok right then, and didn't charge us for it. I like that approach :)

/waves to everyone, hope you're all doing well.

Pebbles73 · 19/12/2013 20:29

Hope it goes ok Mel, are you ttc at the moment or do you have to wait until after the lit?

Was wondering how you were getting on Duggs and sorry you didn't get many make it to day five. I think from what I have been told its always a bit of a risk waiting until day 5 anyway as sometimes none of them make it. The fact that the ones you have put back got to day 5 is a good start and no reason it shouldn't work. Will pm you.

Very interesting though about the sperm dna kicking in on day three and meaning your eggs should be healthy. I was beginning to think mine weren't but maybe is not the case. Although when we had icsi they were quite happy with the sperm. It's such a minefield I just don't know anymore! Anyway keeping everything crossed for you.xx

Waves to everyone and as Mel said hoping 2014 is better for us all.

How is your daughter doing Ari ?