Absolutely I use different spin speeds, and save the high spin speed for sheets, towels and jeans
I used to do it all on the fastest spin, but when I bought my new washing machine, (and by the way I love it to bits - is fab).
I spoke to a washing machine engineer, and he said that very high spin speeds knacker clothes more quickly, which explained why all my dd's clothes looked knackered after doing them all at 1600 on my old machine.