I have had 6,3,2 and newborn while home schooling, sister in law has had 7,5 3,2 and newborn while home schooling, definitely possible. I think since I had csection that school run would have been harder. Reading eggs and mathaletics were great as was leap pad. Lots of reading books drawing etc while I fed baby, but we didn't do lot of structured stuff then. Had to have a sort of routeen though all be it more laid back. It was lovely my then year old being able to spend more time with baby and toddler when they were little, they are so close now.