For various reasons, there's a good chance I'm going to need to drive overseas (in a country I have visited several times before).
It's a technically easy trip, mostly toll roads and highways. I'll have sat nav, phone (with local people expecting me at the other end) and I am a competent driver and have travelled by car round lots of it before - just never driven long distance there alone. Women are generally safe there, but you wouldn't want to break down at night. Also the traffic police can be a little corrupt if they stop foreigners.
I'm doing a similar length/style journey in the UK shortly (to somewhere I have never been before) and I am not batting an eyelid. So why I am so inexplicably nervous about this one? There is no easy alternative way of getting to my destination.
(I'm sure if/when I do it, I'll look back and wonder what I was fussing over, but....)