About 4 years ago, a year after birth of our first child, my wife noticed that one of her eye (balls) was protruding slightly, (kind of Marty Feldmanish) She has a whole load of tests to check for anything behind (tumour)and a range of blood tests. Result nothing. she still has the eye thing but since then has developed an absolutely furious temper. Her moods swing dramatically. A small slight will set her of..its like watching a volcano brew and then erupt..she ends in tears. Sometimes a few hours later its as if it didn't happen. I know blokes can be insensitive pigs and all that but honest to god i am trying so hard and I know this is just not right. Myself and our DS (4) spent our time apologising and trying to calm the anger. Its tearing us apart and I just don't know what to do. She's had follow up blood tests for thyroid I think but nothing seems to result in the sense of a clear diagnosis of anything amiss or a treatment. Does anyone know what this could be? I found something called Pagetts disease on the net but then none of the doctors have come back with this. She's stopped bothering with the the tests.