Anyone had delayed side effects with amitriptyline after three weeks?

[Kirstymariex]

amitriptyline was started 3 weeks ago, i’ve been fine until yesterday i felt so so tired and drunk! i had to nap half way through the day, and felt so groggy and unwell!
same today, just a bit off and so tired! anxiety is peaking too very up and down on 10mg!

has anybody else has side effects? these are all day side effects after 3 weeks 🥹

What dose are you on and when are you taking it? I’ve been on it for years, started on 10mg gradually increased up to 60mg. I was advised it takes 12 hours to wear off so to always take it in the evening - I take mine at 6:30pm with my Pregabalin.

I’ve just come off it and was told it makes you really drowsy. Also told that it takes up to two weeks to take effect.

I took it in the evening so it worked over night. I’m normally an early riser but it made me drowsy first thing.

Did your prescriber give you instructions on how/when to take it?

i am on 10mg i take it at 8pm i have spoken to the nurse practitioner this evening and she has told me to take 5mg as it must be a build up in my system. It’s making me so groggy all day not just for the morning. I keep needing a nap then i’m ok for a bit although i feel ‘off’ and then i need another nap. It’s made me feel quite slow!

I was fine for the first 20 days, yesterday was day 21 and in the morning i felt like i didn’t want to wake up, i did get up and do the school run, then i did a bit of cleaning then it really hit!
i had to have a nap, then when i did the school pick up, i felt drunk! 🥴 It’s made me drowsy all day rather than just in the morning. I take 10mg at 8pm.
my anxiety has been ebbing and flowing up and down since yesterday, i have spoken to the nurse since this post and she’s told me to take 5mg and maybe wean off. She’s going to see me next week for a different medication.

how do you feel coming of? i’ve heard not so great things

Yes it sounds like it could be too strong a dose for you. I moved mine earlier - so taking it around 6.30/7pm which helped me be a bit less tired the next morning.

To be honest, I’ve come off it because I had surgery two weeks ago which has removed the nerve pain I was taking it for. I tapered off for a week - taking a half tablet by the end and don’t think I had any bad effects. However - I was taking a lot of other strong pain meds and still felt quite drowsy so they could’ve masked something.

i think so! it’s awful because it’s making me feel unwell! 🥴
i took half at 6:30pm hopefully this feeling goes away in the next couple of days and i see the GP next week but she wants me to taper off it now.

it’s no good when you have a life to be doing and you feel drowsy, drunk, tired and just awful!🥹 i had to get my husband home for the school run today i didn’t want to feel like i did yesterday i probably shouldn’t have driven yesterday.

how are you feeling now?

I’m sorry to hear you’re feeling so groggy. I hope you feel better when you decrease your dose. And definitely ask the GP for an alternative.

I have come right down off most of my pain meds now so I’m feeling much better - thanks for asking! Just need to remember to still take it slowly with DC at home for summer holidays

i’m hoping to start feeling better after having only half last night and weening off them.
they are the devil it’s so hard to wake up in the mornings and that’s not great i also have a little one i need to be up for🥹

so glad your feeling much better, take it easy these holidays and just do picnics in the garden etc mine love that sort of stuff x