Sertraline is well known for strong vivid dreams. I've been on Sertraline 11 years now and l cannot remember a night ( or a nap) where I've not had a strong and vivid dream. Some are like reading a short story. I always wake up and remember them. Some l can remember for years.. mostly they are very detailed dreams ..only a very rare few have been nightmares. Added note. My friend went on Sertraline a few months ago and asked me about it's connection to vivid dreams.. she started dreaming a lot about sex and sex with strangers..said she woke up so guilty she couldn't tell her husband or her Mormon friends.