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Update on Progesterone only pill for migraine - not helped for me

5 replies

mechanicalpencil · 10/09/2025 19:19

Hi everyone

47 years old, peri.

I have been on the POP for 5 months now, recommend by GP to help with migraine that I have had since a teen (in addition to amitriptyline).

Zelleta 75micrograms Desogesterl

I haven't really noticed much difference to my migraine to be honest, still get them.

Also, haven't had a proper period now for 4 months and so I don't know where I am in my cycle which makes things trickier as for example I knew to avoid alcohol during and just before/after my period as that would induce a migraine, but other times of the month I would be fine. Now, I don't know when that is, so it is pot luck if a I have a glass of something. Had a beer last night and in a lot of pain today.

I also feel my anxiety and general mental health have taken a bit of a nose dive.

Finally, there is the PMT feeling that I seem to have a lot of the time but no period comes...

So, I'm thinking time to come off it.

If you have a POP experience to share for migraine I'd love to hear it! Did it work for you?

OP posts:
Lillygolightly · 10/09/2025 19:27

Yes I tried POP several different brands to try and cope with both contraception and migraines. It didn’t work! What happened for me was that instead of getting a full on migraine say once a week, I got a mini one with aura daily. I was constantly dizzy and nauseous and in the end gave up on any kind of contraception and that is finally when my migraines finally eased up.

mechanicalpencil · 10/09/2025 19:30

Amazing to hear your migraines have ceased @Lillygolightly !!

I have tried a long spell without any contraception but unfortunately didn't help my migraines...

OP posts:
mechanicalpencil · 10/09/2025 20:02

anyone else have any experiences to share?

OP posts:
mechanicalpencil · 11/09/2025 09:40

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OP posts:
mechanicalpencil · 11/09/2025 09:41

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OP posts:
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