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Original poster

Any Drs here? Severe Gastritis from Dexamethasone injections. Can I take Esomeprazole?

7 replies

Iateahorse · 05/12/2023 18:57

I'm midway through 12 days of daily 4mg Dexamethasone intramuscular injections and they have given me severe gastritis. I have lots of 40mg esomeprazole here as home as I suffer with Gastritis often, but I have no idea can take them with the Dex?

OP posts:
Munchyseeds2 · 05/12/2023 19:00

Phone 111 and ask them?

Original poster
Iateahorse · 05/12/2023 19:02

Thanks, sorry I should have mentioned I'm I'm not in the UK so don't have that type of service.

OP posts:
NannyR · 05/12/2023 19:06

Can you ask a pharmacist? At least you know you are getting reliable information from a professional - anyone could claim to be a doctor online.

Original poster
Iateahorse · 05/12/2023 19:16

Yes, that's a good idea. I was hoping to be able to a PPI tonight. But I can wait until tomorrow when I can see a pharmacist. I've been trying to call the Orthopedic surgeon who prescribed it but he's closed for the day.

OP posts:
pharmachameleon · 05/12/2023 19:45

I'm a pharmacist OP and yes longer courses of steroids like dexamethasone should be prescribed with PPIs like esomeprazole. There are no interactions between dexamethasone and esomeprazole-I have linked the dexamethasone injection patient information leaflet and if you look at the section that states 'other medicines and dexamethasone injection' you will see that there are no safety issues with taking both of these medicines together.
Just to confirm you aren't prescribed any other PPIs like omeprazole or lansoprazole? If not then I would take esomeprazole to reduce the gastrointestinal side effects.

www.medicines.org.uk/emc/files/pil.4659.pdf

Original poster
Iateahorse · 05/12/2023 20:04

Thankyou so much @pharmachameleon and for the leaflet. The only PPI I take is esomeprazole, I can't tolerate the others you mentioned. I have boxes of 40mg esomeprazole as I haven't need it for months, until now!

OP posts:
pharmachameleon · 05/12/2023 21:05

All steroids have the common side effect of gastrointestinal discomfort which can lead to a stomach ulcer in more serious cases. Therefore for many patients on steroids like dexamethasone we co-prescribe PPIs for the duration of the steroid course. Very common to use both drugs together. Hope esomeprazole gives you some comfort tonight and you can speak to a doctor tomorrow.

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