Antibiotics have certainly been an important modern medical innovation. But then so are vaccinations.
And it is also important to have safe water & good sanitation, no one's denying that.
But immunisations are a cheap and highly effective way to save children's lives - and they shouldn't wait until we have effective sanitation/water!
"RE polio vaccine. Would I have introduced it? Not the way it was introduced, no. I would have been on the side of the more cautious virologists. I also have issues with the ethics around the use of the HeLa cell line but that's prob another thread. I do think they need to move away from the OPV in developing countries and start using the IPV. "
Why wouldn't you have introduced it - do you not think it was that effective? HeLA is indeed totally separate. As I'm sure you know HeLa wasn't just used for the Polio vaccine - it is in use now and indeed it was used for the development of antibiotics, cervical cancer treatments (as it came from a highly aggressive CC, made particularly aggressive by the particular mutation the HPV virus caused in Henreitta Lacks)...you name it, HeLa is part of it.
"I didn't say delay it. I would split it completely. I don't think mumps and rubella vaccines need to be given to a one year old."
Why not? Can 1 year olds not catch mumps or rubella?
"Just read through all my posts and no, I don't imply that at all. I actually recall that thread because it was just after I had spoken to a few people in PH about the HPV vaccine and they were very concerned that so many people were given the impression that 'this will prevent cancer' and they were worried about falling screening rates (and a shift in dominant strains). I dislike that so many people promote the vaccine (which provides limited protection) and don't promote the importance of screening."
I certainly got the impression you were against HPV vaccination in that thread. Was I wrong?
"Source? HPV testing does not test for pre-cancerous changes. It tests for high-risk HPV types in cervical cells."
news.cancerconnect.com/hpv-testing-found-to-be-more-effective-than-pap-smears-in-evaluating-cervical-cancer-risk/
HPV testing is a more reliable indicator pre-cancerous cell changes that will turn into cancer (I.e. the ones you want to worry about!) than smears alone.
"Are you talking about cGIN? It's quite rare in comparison. How many cases do you think the vaccine is going to prevent?"
I'm talking about Adenocarcinoma in general - some of which is never picked up as CGIN in the first place. I wouldn't say that it's that rare - it accounts for around 1/5 of all cervical cancers and is on the rise, especially amongst young women. Hopefully it will prevent 70% of it - we'll have to wait and see. Even if it only prevented 5% of cases I think it would be worth it, tbh. Here is an article on how hard it is to detect with smears: www.medscape.com/viewarticle/514371.
"Well it's hoped that it will. So far I think they have established that it provides protection against those 2 strains of HPV (16 and 18) for around 5 years. Whether those people go on to develop CC later in life remains to be seen."
Quite - even if it is just for 5 years, the HPV viruses will have fewer hosts to propagate, leading to a long term decline in those getting the virus, and therefore fewer cases of CC.
"No I didn't. I pointed out that it is reducing and it was one of the things being considered by the JCVI in whether or not it was cost effective to introduce. Can you stop making things up please? It wasn't me dismissing it. It was a consideration by the JCVI. I guess they must be a bit 'shaky' too then "
What am I making it up? Do you think Men B should be introduced? I'm confused.
*"Ah, so are you plucking figures out of the air. Good to know.
I know what false positives are thanks "*
No I'm not, and no you don't. What figures have I made up? For a 99.9% accurate test:
for a disease/condition whatever with 1 in a million incidence, a positive result means only a 1 in 1000 or 0.1% chance of having the reaction
for a disease/condition whatever with a 1 in 10,000 incidence, a positive result means only a 1 in 10 or 10% chance of having the reaction
Clear?
"Re incidence of CC falling (as mentioned above) - why do you think that was? Have I tried to attribute the decrease in mortality entirely to screening?"
No - and I haven't said all reductions of Measles were due to the Measles vaccination, just that it was a hugely important component of the reduction, regardless of whether deaths were falling beforehand or not.
I'm trying to point out to you in my previous post that your position seems to be "just the facts, folks" - but you only present facts which are in isolation highly misleading...just as if the only thing I said about CC screening was that it missed over half of all cancers in young women or that it was pretty useless at detecting adenocarcinoma. You might even think that I was anti-screening if I talked that, wouldn't you! (I'm not; Cervical screening is a hugely important public health screening tool that has saved tens of thousands of lives).
Just like you never, ever talk about the good vaccination has done - only its limitations and your discredited theories re: it triggering autism.