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Mirtazapine and weight gain?

54 replies

Thefirsttulip · 16/04/2018 17:47

Hello,

I have been prescribed mirazapine to help with my depression and anxiety. One of the reasons the GP prescribed this one is because of my difficulty sleeping.

I've been reading the side effects and saw one was weight gain.

I looked it up on the internet and lots of people have experienced weight gain on it and there are some comments such as no matter what they do (watch what they eat etc) it doesn't stop the weight gain.

I know if I gain weight I will feel even worse and become very down about it.

Has anyone experienced this drug? If so, what was your experience on it?

Thank you

OP posts:
Thefirsttulip · 16/04/2018 18:59

Bump

OP posts:
hotstepper4 · 16/04/2018 19:06

I won't lie I gained a stone in a month on it so I had to come off it.

I was gutted to do so though because in terms of an antidepressant it was the best one I went on, slept well on it and felt better.

thatcoldfeeling · 16/04/2018 19:09

This was the reason why I refused to take Mirtazapine. I was also not eating at the time and my GP seemed to think weight gain was therefore a positive thing - I completely disagreed. Sometimes weight gain is unbearable (and that is not to say there is anything wrong with any sized body, there isn't, but weight gain can be so difficult to handle no matter what logic may say).

I also took one mirtazapine before realising about the weight gain and felt like actual total hell the next day, completely out of it and nearly crashed my car.

So I have a rather low opinion of it! I take diazepam to help relax at night, and fluoxetine to help with overall mood. Diazepam is also far from ideal but despite it having bad press, the mirtazapine zoning out felt far worse.

Thefirsttulip · 16/04/2018 19:37

Oh no really Sad I haven't taken my first one yet but I was sort of looking forward to a nights sleep.

Two years ago I felt awful because I had gained over a stone in weight through much stress going on (divorce) and lost that stone over a few months because the weight was making me bloody miserable! It was mainly how I felt in clothes that was the problem. So the thought of gaining weight now fills me with dread!

How can it make you gain weight even if you don't eat more?

OP posts:
Thefirsttulip · 16/04/2018 19:40

Last week I took some night nurse because I was desperate to sleep. It's not something I would do regularly but was desperate. It makes me feel really groggy in the morning though so I imagine how this medication will make me feel? Groggy.

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thatcoldfeeling · 16/04/2018 19:46

I think it is that it makes you really hungry and you do end up eating more.

I take sleeping pills quite often but this was worse and almost a delayed reaction. I went to a meeting in the morning the day after I took one, felt a bit wierd but driving home went really odd and then came home and crashed out on the sofa and simply lost 2 hours. I wasn't asleep, I was just zoned out staring into space. That was too much for me, it felt too much. Like I was really insane and needed knocking out!

However that may have just been me. Also I should probably add that as I have an eating disorder my feelings on weight gain are a bit screwy so don't pay too much attention to me!

Perhaps you should try it for a week or so and evaluate? Your GP did obviously have their reasons for deciding this was the best meds for you.

thisisouryrfx18 · 16/04/2018 19:55

@Thefirsttulip ive also taken mitrazapine in the past and i ll b honest the 1st couple of days you do feel very drowsy but if you stick with it it honestly does ease up its great for helping you get back into a normal sleeping pattern. I was only on it for about 6/7 months for anxiety i wasnt sleeping barely eating and felt really on edge constantly. I did gain weight but I dont regret going on the the pills they really helped me out of a hole I was in at the time I still suffer from anxiety but not as bad.

Thefirsttulip · 16/04/2018 20:00

That sounds really scary! I hate feeling "out of control " (have never taken illegal drugs for this very reason.)

The weight gain is putting me off to be honest because I'm so fearful of regaining that weight I put on I give myself "weigh ins" at Boots every so often. Luckily it's never gone back on and I eat normally.

My gp gave me that one because I am not sleeping very well and said it would help with that. I used to have Fluoxetine before (but haven't been on ADs for a while now) but didn't feel like they helped much last time.

Is there one I can take which doesn't make you gain weight? I really feel like I need the meds at the moment but don't want to depress myself further with weight gain and feeling groggy.

OP posts:
thatcoldfeeling · 16/04/2018 20:17

Dothiepin perhaps? But this is GP territory!

Or you could try lemonbalm or valerian tea to see if that takes the edge off it enough for you?

thisisouryrfx18 · 16/04/2018 20:23

@Thefirsttulip im exactly the same even the thought of taking drugs scares me it took me forever to go to gp and ask for help but id reached a breaking point tbh. I honestly would say take them if the sleeps a major problem for u you will feel groggy but know it wont last longer than a couple of days you dont need to stay on them forever you can loseweight when your in a better headspace.

Thefirsttulip · 16/04/2018 20:27

Hmm, think I need to go back to the gp but worried he will just say try them even if I express my fear about weight gain and groggyness.

Been looking at it further on the internet and even found an old thread on MN and it appears 9 out 10 people suffer lots of weight gain with it, even if they don't over eat Sad

I know me and I remember how down I felt when I would struggle to do my trousers up and had a massive muffin top/bum/thighs and puffy face. That's where weight goes on me.

Return to the gp I think as I really don't want to take one of these tablets!

OP posts:
Thefirsttulip · 16/04/2018 20:32

Weight gain made me very down before. I always ranged from 9 and a half to 10 stone (I'm 5ft 3) and near the top of my BMI. When I gained weight before I was 11 stone 4 on the scales and felt very down and depressed about it. It took a few months to loose 20 Ibs but I felt so much better in my body and much more agile (which Is important because I have a physical job) and had more energy. So gaining weight isn't going to do me any favours as it will make me more depressed, have less energy and less agile. I just don't want to risk it Sad

OP posts:
thisisouryrfx18 · 16/04/2018 21:12

OP well only you know whats best for you just tel gp I need to try other pills without weight gain if he says try them just ask to speak to another gp plenty of AD s out there for you to try gd luck keep us posted on how u get on hope you get a sleep tonight.

WillWorkForFood · 16/04/2018 22:09

I was on Mirtazapine for several months.

The weight gain is due to you feeling hungry and craving carbs, hence you eat more. Th drug doesn't change your metabolism or anything and the weight gain can be avoided by being disciplined and strict with yourself, ignoring the hungry feeling - it can be done, but it;snot easy, especially if you're feeling low.

As for sedating side effects - this drug is marvellous for helping you sleep and treating anxiety, absolutely marvellous. The first few days will leave you feeling quite sedated, however you do get used to it and eventually don;t really notice it, although you are aware that you're feeling much calmer than normal and a little 'heavy' in the head - perfectly tolerable, but you;re always aware there's something chilling you out.

Interestingly, lower doses have a greater sedating effect than higher doses. I have tried this and can conform it to be true.

One tip.... when you wake up in the morning, force yourself out of bed and into the shower, or some other stimulating activity - exercise etc. The worst thing you can do is stay in bed, as you'll never fully wake up and can drift off again very easily and stay in a semi-conscious state for hours, with unbelievably weird dreams.No matter how much sleep you have, you'll never quite feel fully refreshed.

For me, in my experience, I was suffering crisis levels of anxiety where my gums were bleeding, my teeth became lose and I hadn't slept for almost a week - the Mirtazapine sorted me out instantly, so for that, it was a wonder drug. It didn't however touch my depression.

ProzacAndWine · 17/04/2018 15:09

I only started Mirtazapine five days ago. I was specifically after something that wouldn't add to my weight issues, but GP thought this was the best option overall, so I'm giving it a go. Sleep deprivation makes me crazy, and it seems to help, so that side is brilliant.

But... for the past day or two I'm constantly hungry! In this mid fog and depression I hardly have the best kind of willpower anyway, or the ability to plan properly and keep to healthy meal plans, so this is not helpful.

If I notice my weight starting to creep up again, this will be yet another drug I'll just have to come off, despite what professionals tell me. :(

ProzacAndWine · 17/04/2018 15:14

*mind fog

I have a long bulimia past, though these days it's very on and off, mostly off, and I seldom have actual huge binges and purges. But I know find myself just fantasising about a humongous binge... Blush

ProzacAndWine · 17/04/2018 15:14

*now, not know...
I'blame the mind fog!

thisisouryrfx18 · 17/04/2018 16:12

I understand if you have EDs its prob not the best and there are loads of ADs out there to try, but I do read a lot of negative comments about mirtazapine that could make it seem really scarey and put people off even trying it. I would honestly say to anyone prescribed it for anxiety imo if you stick with it you wont become a zombie or spaced out, I was worried it would do that to me but it didnt it honestly stopped me from snapping mentally.

ProzacAndWine · 17/04/2018 17:44

thisisouryrfx18 my ED isn't my biggest problem though, and I've been through lots of different meds, so it seems like a valid idea to give this a try.

I'll also add that I haven't been feeling like a zombie at all on this. It's made me feel a bit sleepy in the evenings c. an hour after taking it, and it's helped me fall asleep quicker than I normally. But it definitely hasn't been knocking me out the way sleeping pills or antipsychotics do, and I haven't been feeling tired or zoned out during the day - well, not anymore than I usually do at least!

wfrances · 17/04/2018 18:23

my doctors told me a third of patients will put a lot of weight on , third - a little and a third no weight .
so try it , im lucky , i have no weight gain or increased appetite.

Thefirsttulip · 18/04/2018 16:32

I decided to take it last night and I can barely function today. I feel so tired and lethargic and a bit spaced out. I also woke up starving hungry and have been fighting the urge to eat loads of food. I hate feeling hungry and not being able to eat because I'll gain weight. I'm going to give it a few days but this feels horrible!

OP posts:
thisisouryrfx18 · 18/04/2018 16:50

@Thefirsttulip sorry your feeling crap hun❤ but dont worry i can honestly say it gets easier try and stick with it and see how u feel. Did u sleep gd with it?

Thefirsttulip · 18/04/2018 17:09

I slept ok but I'm so tired with no energy today I feel like I've not slept for a week!

OP posts:
thisisouryrfx18 · 18/04/2018 17:40

I was like that the first3 days are the worst but as i said it will ease up

ProzacAndWine · 18/04/2018 20:58

Yeah... I've had a bulimic episode today and slept three hours in the middle of the day today. Fun drug?

Sorry you're feeling shit, too Flowers

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