Do you enjoy putting words in people's mouths?
As a minimum I'd want science, single/double/triple as options for those who are academic and those that aren't. Single could cover the "life lessons" that I feel are important such as gravity, human anatomy, reproduction, basic chemistry etc.
I'd want maths, but maybe with the option of a more practical subject such as functional skills offers. Managing money, basic tax, basic mental arithmetic, basic algebra.
English, one or both.
Art, music, drama etc. Something creative.
PE, with options for something like dance.
Languages for all students, full GCSEs are great but maybe also a basic course with one language a term, for conversational purposes.
More vocational courses such as construction, electronics, woodwork, graphics, food technology.
Computer based courses, ICT for example. For students who aren't taking it as a GCSE I'd also have a compulsory short course where you learn the basics of excel, word, email, internet safety.
Citizenship: learning about healthy relationships, sex education, contributing to society etc.
All of these, in my opinion, give a better life grounding than learning Latin at GCSE. I'd say the same about plenty of other subjects that can be picked up at A Level for those students that choose to enter higher education.